Fibroblasts Concept

subject area of

• 3D bioprinting of heterogeneous bi- and tri-layered hollow channels within gel scaffolds using scalable multi-axial microfluidic extrusion nozzle  Journal Articles
• IRAK-4 Mutation (Q293X): Rapid Detection and Characterization of Defective Post-Transcriptional TLR/IL-1R Responses in Human Myeloid and Non-Myeloid Cells  Journal Articles
• A Fatal, Systemic Mitochondrial Disease with Decreased Mitochondrial Enzyme Activities, Abnormal Ultrastructure of the Mitochondria and Deficiency of Heat Shock Protein 60  Journal Articles
• A Multivariate Growth Curve Model for Ranking Genes in Replicated Time Course Microarray Data  Journal Articles
• A Recurrent De Novo Heterozygous COG4 Substitution Leads to Saul-Wilson Syndrome, Disrupted Vesicular Trafficking, and Altered Proteoglycan Glycosylation  Journal Articles
• A UV-specific endonucleolytic activity present in human cell extracts  Journal Articles
• A cell-specific regulatory region of the human ABO blood group gene regulates the neighborhood gene encoding odorant binding protein 2B  Journal Articles
• A combination of MSH2 DNA mismatch repair deficiency and expression of the SV40 large T antigen results in cisplatin resistance of mouse embryonic fibroblasts  Journal Articles
• A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes  Journal Articles
• A deficiency in the repair of UV and γ-ray damaged DNA in fibroblasts from Cockayne's syndrome  Journal Articles
• A mutation in the TMEM65 gene results in mitochondrial myopathy with severe neurological manifestations  Journal Articles
• A new direction in the pathogenesis of idiopathic pulmonary fibrosis?  Journal Articles
• A novel multi-ancestry proteome-wide Mendelian randomization study implicates extracellular proteins, tubular cells, and fibroblasts in estimated glomerular filtration rate regulation  Journal Articles
• A novel profibrotic mechanism mediated by TGFβ‐stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells  Journal Articles
• A patient-derived cellular model for Huntington’s disease reveals phenotypes at clinically relevant CAG lengths  Journal Articles
• A specific ultrastructural stain for arylsulfatase A activity in human cultured fibroblasts.  Journal Articles
• ATP stimulates Ca2+-waves and gene expression in cultured human pulmonary fibroblasts  Journal Articles
• Acquisition of pluripotency through continued environmental influence on OCT4-induced plastic human fibroblasts  Journal Articles
• Action of surface-active agents on arylsulfatase-C of human cultured fibroblasts  Journal Articles
• Activated Src requires Cadherin-11, Rac, and gp130 for Stat3 activation and survival of mouse Balb/c3T3 fibroblasts  Journal Articles
• Activation of Neural Cell Fate Programs Toward Direct Conversion of Adult Human Fibroblasts into Tri-Potent Neural Progenitors Using OCT-4  Journal Articles
• Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD  Journal Articles
• Alveolar Macrophage/Peripheral Blood Monocyte-Derived Factors Modulate Proliferation of Primary Lines of Human Lung Fibroblasts  Journal Articles
• Amino acid substitutions of the P2 residue of human antithrombin that either enhance or impair function  Journal Articles
• An Accessory to the ‘Trinity’: SR-As Are Essential Pathogen Sensors of Extracellular dsRNA, Mediating Entry and Leading to Subsequent Type I IFN Responses  Journal Articles
• An alternative regulatory pathway of the acute phase response: the role of fibroblast-derived interferon-β 2  Journal Articles
• An investigation into the effect of amphiphilic siloxane oligomers on dermal fibroblasts  Journal Articles
• Analysis of DNA repair in XP–HeLa hybrids; lack of correlation between excision repair of u.v. damage and adenovirus reactivation in an XP(D)-like cell line  Journal Articles
• Anchorage-independent colony growth of pulmonary fibroblasts derived from fibrotic human lung tissue.  Journal Articles
• Angiotensin-converting enzyme 2 expression in COPD and IPF fibroblasts: the forgotten cell in COVID-19  Journal Articles
• Apatite Determination and Distribution in an Early Stage of Gallbladder Calcification  Journal Articles
• Aryl Hydrocarbon Receptor-Dependent Retention of Nuclear HuR Suppresses Cigarette Smoke-Induced Cyclooxygenase-2 Expression Independent of DNA-Binding  Journal Articles
• Association of steroid sulfatase with one of the arylsulfatase C isozymes in human fibroblasts.  Journal Articles
• Autologous fibroblast implantation. Feasibility and potential problems in gene replacement therapy.  Journal Articles
• Autoradiographic detection of diphtheria toxin resistant mutants in human diploid fibroblasts  Journal Articles
• Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types.  Journal Articles
• Beneficial effects of resveratrol on respiratory chain defects in patients' fibroblasts involve estrogen receptor and estrogen-related receptor alpha signaling  Journal Articles
• Biochemical characterization of arylsulfatase-C isozymes in human fibroblasts  Journal Articles
• Biochemical variability of arylsulphatases‐A,‐B and‐C in cultured fibroblasts from patients with multiple sulphatase deficiency  Journal Articles
• Biomimetic collagen-sodium alginate-titanium oxide (TiO2) 3D matrix supports differentiated periodontal ligament fibroblasts growth for periodontal tissue regeneration  Journal Articles
• Bone marrow‐derived mitochondrial DNA has limited capacity for inter‐tissue transfer in vivo  Journal Articles
• Bronchial myofibroblasts and tissue remodelling in asthma.  Journal Articles
• C/EBPβ (NF-M) Is Essential for Activation of the p20K Lipocalin Gene in Growth-Arrested Chicken Embryo Fibroblasts  Journal Articles
• COX19 mediates the transduction of a mitochondrial redox signal from SCO1 that regulates ATP7A-mediated cellular copper efflux  Journal Articles
• Ca²⁺/calmodulin-dependent protein kinase IIβ and IIδ mediate TGFβ-induced transduction of fibronectin and collagen in human pulmonary fibroblasts  Journal Articles
• Cadherin-11–mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β  Journal Articles
• Calcium Homeostasis and Ionic Mechanisms in Pulmonary Fibroblasts  Journal Articles
• Calcium antagonistic actions of tetrandrine depend on cell types.  Journal Articles
• Capacity of UV‐lrradiated Human Fibroblasts to Support Adenovirus DNA Synthesis Correlates with Transcription‐Coupled Repair and is Reduced in SV40‐Transformed Cells and Cells Expressing Mutant p53  Journal Articles
• Catecholamines Induce Endoplasmic Reticulum Stress Via Both Alpha and Beta Receptors  Journal Articles
• Cell adhesion and proliferation on hydrophilic dendritically modified surfaces  Journal Articles
• Cell-specific Gene Expression in Patients with Usual Interstitial Pneumonia  Journal Articles
• Cells Exposed to Sublethal Oxidative Stress Selectively Attract Monocytes/Macrophages via Scavenger Receptors and MyD88-Mediated Signaling  Journal Articles
• Cellular Protein WDR11 Interacts with Specific Herpes Simplex Virus Proteins at thetrans-Golgi Network To Promote Virus Replication  Journal Articles
• Cellular interactions in lung inflammation and immunity.  Journal Articles
• Cellular processes of v-Src transformation revealed by gene profiling of primary cells - Implications for human cancer  Journal Articles
• Cellularized Bilayer Pullulan-Gelatin Hydrogel for Skin Regeneration  Journal Articles
• Changes in mitochondrial shape and distribution induced by ethacrynic acid and the transient formation of a mitochondrial reticulum  Journal Articles
• Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration  Journal Articles
• Chromosome content and ultrastructure of radiation-induced micronuclei  Journal Articles
• Cigarette Smoke Suppresses Type I Interferon-Mediated Antiviral Immunity in Lung Fibroblast and Epithelial Cells  Journal Articles
• Circulating fibrocytes are not disease-specific prognosticators in idiopathic pulmonary fibrosis  Journal Articles
• Clear cell renal cell carcinoma induces fibroblast-mediated production of stromal periostin  Journal Articles
• Clinical variability in maternally inherited leber hereditary optic neuropathy with the G14459A mutation  Journal Articles
• Cloning of the cDNA and Gene Encoding Mouse Lysosomal Sialidase and Correction of Sialidase Deficiency in Human Sialidosis and Mouse SM/J Fibroblasts  Journal Articles
• Comparative studies of host-cell reactivation, cellular capacity and enhanced reactivation of herpes simplex virus in normal, xeroderma pigmentosum and Cockayne syndrome fibroblasts  Journal Articles
• Competence for collagenase gene expression by tissue fibroblasts requires activation of an interleukin 1 alpha autocrine loop.  Journal Articles
• Complete elimination of a pathogenic homoplasmic mtDNA mutation in one generation  Journal Articles
• Complex expression pattern of the CEF-4 cytokine in transformed and mitogenically stimulated cells.  Journal Articles
• Construction of a recombinant adenovirus containing the den V gene from bacteriophage T4 which can partially restore the DNA repair deficiency in xeroderma pigmentosum fibroblasts  Journal Articles
• Contribution of Electron Microscopy to Understanding Cellular Differentiation in Mesenchymal Tumors of the Gastrointestinal Tract: A Study of 82 Tumors  Journal Articles
• Controlling cellular activity by manipulating silicone surface roughness  Journal Articles
• Cutting Edge: FimH Adhesin of Type 1 Fimbriae Is a Novel TLR4 Ligand  Journal Articles
• Cytogenetic dose–response and adaptive response in cells of ungulate species exposed to ionizing radiation  Journal Articles
• Cytokine‐induced expression of mRNAs for chemotactic factors in human synovial cells and fibroblasts  Journal Articles
• Cytoskeletal protein Flightless (Flii) is elevated in chronic and acute human wounds and wound fluid: neutralizing its activity in chronic but not acute wound fluid improves cellular proliferation  Journal Articles
• DRB resistance in Chinese hamster and human cells: Genetic and biochemical characteristics of the selection system  Journal Articles
• Decreased expression of the NF-κB family member RelB in lung fibroblasts from Smokers with and without COPD potentiates cigarette smoke-induced COX-2 expression  Journal Articles
• Decreased repair of gamma ray damaged DNA in progeria  Journal Articles
• Deficient base excision repair of oxidative DNA damage induced by methylene blue plus visible light in xeroderma pigmentosum group C fibroblasts  Journal Articles
• Deficient glycosylation of arylsulfatase A in pseudo arylsulfatase-A deficiency  Journal Articles
• Delayed expression of enhanced reactivation and decreased mutagenesis of UV-irradiated adenovirus in UV-irradiated ataxia telangiectasia fibroblasts  Journal Articles
• Delayed expression of lethal mutations and genomic instability in the progeny of human epithelial cells that survived in a bystander-killing environment  Journal Articles
• Delivery of Recombinant Gene Products with Microencapsulated Cells In Vivo  Journal Articles
• Depletion of poly(ADP-ribose) polymerase-1 reduces host cell reactivation of a UV-damaged adenovirus-encoded reporter gene in human dermal fibroblasts  Journal Articles
• Derivation of human induced pluripotent stem cells through continued exposure of OCT4-induced plastic human fibroblasts to reprogramming media  Journal Articles
• Detecting single cell interferon-beta production using a fluorescent reporter telomerase-immortalized human fibroblast cell line  Journal Articles
• Detection and quantification of endoplasmic reticulum stress in living cells using the fluorescent compound, Thioflavin T  Journal Articles
• Detection of an Involvement of the Human Mismatch Repair Genes hMLH1 and hMSH2 in Nucleotide Excision Repair Is Dependent on UVC Fluence to Cells  Journal Articles
• Detection of arylsulfatase A activity after electrophoresis in polyacrylamide gels: Problems and solutions  Journal Articles
• Development of small alginate microcapsules for recombinant gene product delivery to the rodent brain  Journal Articles
• Diacylglycerol Kinase Delta Promotes Lipogenesis  Journal Articles
• Diagnosis of Complex I Deficiency in Patients with Lactic Acidemia Using Skin Fibroblast Cultures  Journal Articles
• Diagnosis of Pseudo-Arylsulfatase A Deficiency with Electrophoretic Techniques  Journal Articles
• Differences in the Fibrogenic Response after Transfer of Active Transforming Growth Factor-β1 Gene to Lungs of “Fibrosis-prone” and “Fibrosis-resistant” Mouse Strains  Journal Articles
• Differential assay of arylsulfatase A and B activities: A sensitive method for cultured human cells  Journal Articles
• Differential inhibition of collagenase and interleukin-1alpha gene expression in cultured corneal fibroblasts by TGF-beta, dexamethasone, and retinoic acid.  Journal Articles
• Direct conversion of human fibroblasts to multilineage blood progenitors  Journal Articles
• Disruption of Calcium Signaling in Fibroblasts and Attenuation of Bleomycin-Induced Fibrosis by Nifedipine  Journal Articles
• Double aneuploidy (47,XX,21+-45,X) arising through simultaneous double non-disjunction.  Journal Articles
• ERCC1/XPF Removes the 3′ Overhang from Uncapped Telomeres and Represses Formation of Telomeric DNA-Containing Double Minute Chromosomes  Journal Articles
• ERK activity facilitates activation of the S-phase DNA damage checkpoint by modulating ATR function  Journal Articles
• Effect of Human Wharton's Jelly Mesenchymal Stem Cell Paracrine Signaling on Keloid Fibroblasts  Journal Articles
• Effect of ammonium chloride on subcellular distribution of lysosomal enzymes in human fibroblasts  Journal Articles
• Effect of histamine on proliferation of normal human adult lung fibroblasts.  Journal Articles
• Effects of hTERT on metal ion-induced genomic instability  Journal Articles
• Effects of neurotrophic factors and cell substrates on the differentiation of a sympathoadrenal progenitor cell line.  Journal Articles
• Electrophoretic variants of human 6‐phosphogluconate dehydrogenase: population and family studies and description of a new variant  Journal Articles
• Electrophysiological characterization of voltage-dependent calcium currents and TRPV4 currents in human pulmonary fibroblasts  Journal Articles
• Encapsulation of various recombinant mammalian cell types in different alginate microcapsules  Journal Articles
• Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event  Journal Articles
• Energy-stress-mediated AMPK activation inhibits ferroptosis  Journal Articles
• Enhanced expression from the human cytomegalovirus immediate-early promoter in a non-replicating adenovirus encoded reporter gene following cellular exposure to chemical DNA damaging agents  Journal Articles
• Enhanced reactivation and mutagenesis of UV-irradiated adenovirus in normal human fibroblasts  Journal Articles
• Ethylmalonic and methylsuccinic aciduria in ethylmalonic encephalopathy arise from abnormal isoleucine metabolism  Journal Articles
• ExCeL: combining extrusion printing on cellulose scaffolds with lamination to createin vitrobiological models  Journal Articles
• Expression of Human Factor IX by Microencapsulated Recombinant Fibroblasts  Journal Articles
• Expression of SV40 large T antigen, but not small t antigen, is required for the induction of chromosomal aberrations in transformed human cells  Journal Articles
• Expression of a novel gene product by transplants of genetically modified primary fibroblasts in the central nervous system  Journal Articles
• Expression of an adenovirus encoded reporter gene and its reactivation following UVC and oxidative damage in cultured fish cells  Journal Articles
• Expression pattern of X-linked genes in sex chromosome aneuploid bovine cells  Journal Articles
• Extracellular Matrix and Fibrocyte Accumulation in BALB/c Mouse Lung upon Transient Overexpression of Oncostatin M  Journal Articles
• Extracellular Signal-Regulated Kinase 2 and CHOP Restrict the Expression of the Growth Arrest-Specific p20K Lipocalin Gene to G₀  Journal Articles
• Extreme Dark Cytotoxicity of Nile Blue A in Normal Human Fibroblasts¶  Journal Articles
• FGF19 Is Downregulated in Idiopathic Pulmonary Fibrosis and Inhibits Lung Fibrosis in Mice  Journal Articles
• Factors regulating the multiplication of animal cells in culture  Journal Articles
• Fetal scarless wound healing.  Journal Articles
• Fibroblast growth factor-1 attenuates TGF-β1-induced lung fibrosis  Journal Articles
• Fibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients  Journal Articles
• Fibroblasts and Other Structural Cells in Airway Inflammation  Journal Articles
• Fibrocytes and fibroblasts—Where are we now  Journal Articles
• Fibrocytes in chronic lung disease – Facts and controversies  Journal Articles
• Fibrocytes in pulmonary fibrosis: a brief synopsis  Journal Articles
• Fibrotic extracellular matrix induces release of extracellular vesicles with pro-fibrotic miRNA from fibrocytes  Journal Articles
• First‐trimester diagnosis of Hunter syndrome (MPS II)  Journal Articles
• Follistatin promotes adipocyte differentiation, browning, and energy metabolism  Journal Articles
• GABARAP is a determinant of apoptosis in growth-arrested chicken embryo fibroblasts  Journal Articles
• Gamma-Ray-Enhanced Reactivation of Irradiated Adenovirus in Xeroderma Pigmentosum and Cockayne Syndrome Fibroblasts  Journal Articles
• Gaucher disease. III. Substrate specificity of glucocerebrosidase and the use of nonlabeled natural substrates for the investigation of patients.  Journal Articles
• Gaucher's Disease II. Studies on the Kinetics of β-Glucosidase and the Effects of Sodium Taurocholate in Normal and Gaucher Tissues  Journal Articles
• Gene dosage effects in human diploid and tetraploid fibroblasts  Journal Articles
• Glucosamine induces ER stress by disrupting lipid-linked oligosaccharide biosynthesis andN-linked protein glycosylation  Journal Articles
• Glycosyltransferases and Glycosaminoglycans in Bleomycin and Transforming Growth Factor-β1–Induced Pulmonary Fibrosis  Journal Articles
• Growth and Colony‐Stimulating Factors Mediate Eosinophil Fibroblast Interactions in Chronic Airway Inflammationa  Journal Articles
• HSP60 chaperone deficiency disrupts the mitochondrial matrix proteome and dysregulates cholesterol synthesis.  Journal Articles
• Heat-shock enhanced reactivation of a UV-damaged reporter gene in human cells involves the transcription coupled DNA repair pathway  Journal Articles
• Heparan Sulfate Interacting Protein (HIP/L29) Negatively Regulates Growth Responses to Basic Fibroblast Growth Factor in Gingival Fibroblasts  Journal Articles
• Herpes simplex virus glycoproteins E and I facilitate cell-to-cell spread in vivo and across junctions of cultured cells  Journal Articles
• Heterogeneity of lysosomes in human fibroblasts  Journal Articles
• Heterogeneous Proliferative Characteristics of Human Adult Lung Fibroblast Lines and Clonally Derived Fibroblasts from Control and Fibrotic Tissue  Journal Articles
• High-Throughput Screening for Human Lysosomal β-N-Acetyl Hexosaminidase Inhibitors Acting as Pharmacological Chaperones  Journal Articles
• High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry  Journal Articles
• Host cell reactivation of gene expression for an adenovirus-encoded reporter gene reflects the repair of UVC-induced cyclobutane pyrimidine dimers and methylene blue plus visible light-induced 8-oxoguanine  Journal Articles
• Host cell reactivation of sunlamp‐exposed adenovirus in fibroblasts from patients with bloom's syndrome, ataxia telangiectasia, and huntington's disease  Journal Articles
• HuR drives lung fibroblast differentiation but not metabolic reprogramming in response to TGF-β and hypoxia  Journal Articles
• Human ESC colony formation is dependent on interplay between self‐renewing hESCs and unique precursors responsible for niche generation  Journal Articles
• Human Lung Fibroblast-derived Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Mediates Eosinophil Survival In Vitro  Journal Articles
• Human Wharton’s jelly mesenchymal stem cells promote skin wound healing through paracrine signaling  Journal Articles
• Human antigen R promotes lung fibroblast differentiation to myofibroblasts and increases extracellular matrix production  Journal Articles
• Human bronchial and parenchymal fibroblasts display differences in basal inflammatory phenotype and response to IL‐17A  Journal Articles
• Human cells deficient in transcription-coupled repair show prolonged activation of the Jun N-terminal kinase and increased sensitivity following cisplatin treatment  Journal Articles
• Human fibroblast strains showing increased sensitivity or resistance to ethidium bromide  Journal Articles
• Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex  Journal Articles
• ICP0 Prevents RNase L-Independent rRNA Cleavage in Herpes Simplex Virus Type 1-Infected Cells  Journal Articles
• Identification of Pharmacological Chaperones for Gaucher Disease and Characterization of Their Effects on β‐Glucocerebrosidase by Hydrogen/Deuterium Exchange Mass Spectrometry  Journal Articles
• Identification of a Novel Pathway Essential for the Immediate-Early, Interferon-Independent Antiviral Response to Enveloped Virions  Journal Articles
• Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy  Journal Articles
• Igf1r⁺/CD34⁺ immature ICC are putative adult progenitor cells, identified ultrastructurally as fibroblast‐like ICC in Ws/Ws rat colon  Journal Articles
• Imaging of Fibroblast Activation Protein in Cancer Xenografts Using Novel (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine-Based Small Molecules  Journal Articles
• Immortalized human myotonic dystrophy muscle cell lines to assess therapeutic compounds  Journal Articles
• Immune-inflammatory functions of fibroblasts  Journal Articles
• Impaired c-src activation and motility defects in PEA3-null fibroblasts  Journal Articles
• In vitro correction of iduronate-2-sulfatase deficiency by adenovirus-mediated gene transfer  Journal Articles
• Incomplete complementation of the DNA repair defect in cockayne syndrome cells by the denV gene from bacteriophage T4 suggests a deficiency in base excision repair  Journal Articles
• Increased Radiosensitivity in Cells of Two Human Cell Lines Treated with Bystander Medium from Irradiated Repair-Deficient Cells  Journal Articles
• Increased deposition of chondroitin/dermatan sulfate glycosaminoglycan and upregulation of β1,3-glucuronosyltransferase I in pulmonary fibrosis  Journal Articles
• Increased expression of p53 enhances transcription-coupled repair and global genomic repair of a UVC-damaged reporter gene in human cells  Journal Articles
• Induction of Apoptotic Cell Death Specifically in Rat and Human Cancer Cells by Pancratistatin  Journal Articles
• Induction of Cetacean Cytochrome P4501A1 by  -Naphthoflavone Exposure of Skin Biopsy Slices  Journal Articles
• Induction of MMP-1, MMP-3 and TIMP-1 in normal dermal fibroblasts by chronic venous leg ulcer wound fluid*  Journal Articles
• Inflammation and dysregulated fibroblast proliferation--new mechanisms?  Journal Articles
• Influence of the proto-oncogene c-fos on cisplatin sensitivity  Journal Articles
• Inhalation: A means to explore and optimize nintedanib's pharmacokinetic/pharmacodynamic relationship  Journal Articles
• Inhibition of fibroblast to myofibroblast transition by halofuginone contributes to the chemotherapy-mediated antitumoral effect  Journal Articles
• Innate Cellular Response to Virus Particle Entry Requires IRF3 but Not Virus Replication  Journal Articles
• Innate Immune Cytokines, Fibroblast Phenotypes, and Regulation of Extracellular Matrix in Lung  Journal Articles
• Innervated Coculture Device to Model Peripheral Nerve-Mediated Fibroblast Activation.  Journal Articles
• Integrated Stress Response Modulates Cellular Redox State via Induction of Cystathionine γ-Lyase  Journal Articles
• Interaction between oncostatin M, interleukin 1 and prostaglandin E2 in induction of IL-6 expression in human fibroblasts  Journal Articles
• Interaction of Peptide Substrates of Fibroblast Collagenase with Divalent Cations: Ca2+ Binding by Substrate as a Suggested Recognition Signal for Collagenase Action  Journal Articles
• Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.  Journal Articles
• Interferon-Dependent Induction of Clr-b during Mouse Cytomegalovirus Infection Protects Bystander Cells from Natural Killer Cells via NKR-P1B-Mediated Inhibition  Journal Articles
• Interleukin-1α inhibits transforming growth factor-β1 and β2-induced extracellular matrix production, remodeling and signaling in human lung fibroblasts: Master regulator in lung mucosal repair  Journal Articles
• Interrelationships of endoplasmic reticulum, mitochondria, intermediate filaments, and microtubules—a quadruple fluorescence labeling study  Journal Articles
• Intracellular distribution of DNA internalized through calcium phosphate precipitation  Journal Articles
• Intrathymic implants of genetically modified fibroblasts  Journal Articles
• Investigation of promoter function in human and animal cells infected with human recombinant adenoviruses expressing rotavirus antigen VP7sc  Journal Articles
• Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency  Journal Articles
• JunD/AP-1 Antagonizes the Induction of DAPK1 To Promote the Survival of v-Src-Transformed Cells  Journal Articles
• Lack of evidence for a high-affinity sarcosinamide carrier or a catecholamine carrier in Calu-1 lung-cancer cells, HT-29 colon-cancer cells, and DHF fibroblasts  Journal Articles
• Let It Be  Journal Articles
• Lethal Cardiac Tachyarrhythmia in a Patient with Neonatal Carnitine-Acylcarnitine Translocase Deficiency  Journal Articles
• Lipid storage myopathy, ichthyosis, and steatorrhea  Journal Articles
• Lipopolysaccharide Induces Expression of Granulocyte/Macrophage Colony-stimulating Factor, Interleukin-8, and Interleukin-6 in Human Nasal, but Not Lung, Fibroblasts: Evidence for Heterogeneity within the Respiratory Tract  Journal Articles
• Localization of P32 protein (gC1q-R) in mitochondria and at specific extramitochondrial locations in normal tissues  Journal Articles
• Long Double-Stranded RNA Induces an Antiviral Response Independent of IFN Regulatory Factor 3, IFN-β Promoter Stimulator 1, and IFN  Journal Articles
• Loss of CD117 (c-kit)- and CD34-Positive ICC and Associated CD34-Positive Fibroblasts Defines a Subpopulation of Chronic Intestinal Pseudo-obstruction  Journal Articles
• Low levels of the AhR in chronic obstructive pulmonary disease (COPD)-derived lung cells increases COX-2 protein by altering mRNA stability  Journal Articles
• Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis  Journal Articles
• Lung fibroblast clones from normal and fibrotic subjects differ in hyaluronan and decorin production and rate of proliferation  Journal Articles
• MBNL proteins repress ES-cell-specific alternative splicing and reprogramming  Journal Articles
• MN1 C-terminal truncation syndrome is a novel neurodevelopmental and craniofacial disorder with partial rhombencephalosynapsis  Journal Articles
• Magnetic assembly of 3D cell clusters: visualizing the formation of an engineered tissue  Journal Articles
• Male Sexual Dysfunction in Mice Bearing Targeted Mutant Alleles of thePEA3 etsGene  Journal Articles
• Manganese Superoxide Dismutase Levels Are Elevated in a Proportion of Amyotrophic Lateral Sclerosis Patient Cell Lines  Journal Articles
• Marked clinical difference between two sibs affected with juvenile metachromatic leukodystrophy  Journal Articles
• Mast Cells and Fibrosis—Who's on First?  Journal Articles
• Matrix metalloproteinase 10 promotion of collagenolysis via procollagenase activation: Implications for cartilage degradation in arthritis  Journal Articles
• Medium from irradiated human epithelial cells but not human fibroblasts reduces the clonogenic survival of unirradiated cells  Journal Articles
• Mesenchymal Stromal Cells but Not Cardiac Fibroblasts Exert Beneficial Systemic Immunomodulatory Effects in Experimental Myocarditis  Journal Articles
• Methodologies in creating skin substitutes  Journal Articles
• Microtubules, mitochondria, and molecular chaperones: a new hypothesis for in vivo assembly of microtubules  Journal Articles
• Mitogen-activated protein kinases Erk1/2 and p38 are required for maximal regulation of TIMP-1 by oncostatin M in murine fibroblasts  Journal Articles
• Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis  Journal Articles
• Modified Dendrimer Cross-Linked Collagen-Based Matrices  Journal Articles
• Modulation of radiation-induced strand break repair by cisplatin in mammalian cells  Journal Articles
• Molecular Evidence for OCT4-Induced Plasticity in Adult Human Fibroblasts Required for Direct Cell Fate Conversion to Lineage Specific Progenitors  Journal Articles
• Molecular cloning and sequence of porcine interleukin 6 cDNA and expression of mRNA in synovial fibroblasts in vitro  Journal Articles
• Montelukast Treatment Attenuates the Increase in Myofibroblasts Following Low-Dose Allergen Challenge  Journal Articles
• Morphological Alterations in the Ischaemic Heart  Journal Articles
• Mouse NGF promoter upstream sequences do not affect gene expression in mouse fibroblasts  Journal Articles
• Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8–mediated activation of TGF-β  Journal Articles
• Mucolipidosis II. The clinical, radiological and biochemical features in three cases  Journal Articles
• Murine Oncostatin M Stimulates Mouse Synovial Fibroblasts in Vitro and Induces Inflammation and Destruction in Mouse Joints in Vivo  Journal Articles
• Mutations That Alter the Carboxy-Terminal-Propeptide Cleavage Site of the Chains of Type I Procollagen Are Associated With a Unique Osteogenesis Imperfecta Phenotype  Journal Articles
• Mutations in RAB39B in individuals with intellectual disability, autism spectrum disorder, and macrocephaly  Journal Articles
• Myofibroblast Markers and Microscopy Detection Methods in Cell Culture and Histology  Chapters
• Myofibroblast involvement in the allergen-induced late response in mild atopic asthma.  Journal Articles
• Myofibroblastic Sarcoma in Meningioma: A New Variant of “Metaplastic” Meningioma  Journal Articles
• Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting their differentiation into myofibroblasts  Journal Articles
• Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis  Journal Articles
• Neutrophilic Differentiation Induced by Human Upper Airway Fibroblast-derived Granulocyte/Macrophage Colony-stimulating Factor (GM-CSF)  Journal Articles
• Nodular Lesions of Choroid Plexus in Hurler Disease  Journal Articles
• Non-viral transfer approaches for the gene therapy of mucopolysaccharidosis type II (Hunter syndrome)  Conferences
• Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells  Journal Articles
• Novel Function of PERK as a Mediator of Force-induced Apoptosis  Journal Articles
• Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three-dimensional protein structure  Journal Articles
• Oncostatin M (OSM) primes IL-13- and IL-4-induced eotaxin responses in fibroblasts: Regulation of the type-II IL-4 receptor chains IL-4Rα and IL-13Rα1  Journal Articles
• Oncostatin M Regulates Eotaxin Expression in Fibroblasts and Eosinophilic Inflammation in C57BL/6 Mice  Journal Articles
• Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells  Journal Articles
• Oncostatin M induction of eotaxin-1 expression requires the convergence of PI3′K and ERK1/2 MAPK signal transduction pathways  Journal Articles
• Oncostatin M inhibits IL-1-induced expression of IL-8 and granulocyte-macrophage colony-stimulating factor by synovial and lung fibroblasts.  Journal Articles
• Oncostatin M stimulates monocyte chemoattractant protein‐1‐ and interleukin‐1‐induced matrix metalloproteinase‐1 production by human synovial fibroblasts in vitro  Journal Articles
• Oncostatin M-Induced IL-6 Expression in Murine Fibroblasts Requires the Activation of Protein Kinase Cδ  Journal Articles
• One-pot, multicomponent synthesis of 2,3-disubstituted quinazolin-ones with potent and selective activity against Toxoplasma gondii  Journal Articles
• Onset of Human Cytomegalovirus Replication in Fibroblasts Requires the Presence of an Intact Vimentin Cytoskeleton  Journal Articles
• Opposing Roles of C/EBPβ and AP-1 in the Control of Fibroblast Proliferation and Growth Arrest-specific Gene Expression  Journal Articles
• Ovarian Thecal/Interstitial Cells Produce an Epidermal Growth Factor-Like Substance*  Journal Articles
• Overexpression of granulocyte-macrophage colony-stimulating factor induces pulmonary granulation tissue formation and fibrosis by induction of transforming growth factor-beta 1 and myofibroblast accumulation.  Journal Articles
• Oxidative stress contributes to the induction and persistence of TGF-β1 induced pulmonary fibrosis  Journal Articles
• POLRMT mutations impair mitochondrial transcription causing neurological disease  Journal Articles
• Pancratistatin Selectively Targets Cancer Cell Mitochondria and Reduces Growth of Human Colon Tumor Xenografts  Journal Articles
• Pancratistatin: A natural anti-cancer compound that targets mitochondria specifically in cancer cells to induce apoptosis  Journal Articles
• Particulate debris from a titanium metal prosthesis induces genomic instability in primary human fibroblast cells  Journal Articles
• Peroxisomal D-bifunctional protein deficiency  Journal Articles
• Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis  Journal Articles
• Platelet derived growth factor-evoked Ca2+ wave and matrix gene expression through phospholipase C in human pulmonary fibroblast  Journal Articles
• Pleiotropic Action of AP-1 in v-Src-Transformed Cells  Journal Articles
• Poly ADP-ribose signaling is dysregulated in Huntington disease.  Journal Articles
• Porcine Collagenase from Synovial Fibroblasts: cDNA Sequence and Modulation of Expression of RNA In Vitro by Various Cytokines  Journal Articles
• Potential of nintedanib in treatment of progressive fibrosing interstitial lung diseases  Journal Articles
• Potential roles for p53 in nucleotide excision repair  Journal Articles
• Presence of a lysosomal enzyme, arylsulfatase-A, in the prelysosome-endosome compartments of human cultured fibroblasts.  Journal Articles
• Profound DNA methylomic differences between single- and multi-fraction alpha irradiations of lung fibroblasts  Journal Articles
• Progressive Transforming Growth Factor β1–induced Lung Fibrosis Is Blocked by an Orally Active ALK5 Kinase Inhibitor  Journal Articles
• Properties of Poly(ethylene glycol) Hydrogels Cross-Linked via Strain-Promoted Alkyne–Azide Cycloaddition (SPAAC)  Journal Articles
• Prostaglandin E2 enhances interleukin 8 (IL-8) and IL-6 but inhibits GMCSF production by IL-1 stimulated human synovial fibroblasts in vitro.  Journal Articles
• Prostaglandin E₂ inhibits profibrotic function of human pulmonary fibroblasts by disrupting Ca²⁺ signaling  Journal Articles
• Proteoglycans decorin and biglycan differentially modulate TGF-β-mediated fibrotic responses in the lung  Journal Articles
• Pseudo arylsulfatase A deficiency Biosynthesis of an abnormal arylsulfatase A  Journal Articles
• Pseudo arylsulfatase-A deficiency in healthy individuals: genetic and biochemical relationship to metachromatic leukodystrophy.  Journal Articles
• Pulmonary Hypertension and Idiopathic Pulmonary Fibrosis  Journal Articles
• Purine nucleosides and nucleotides stimulate proliferation of a wide range of cell types  Journal Articles
• Qualitative characteristics of the beta-glucosidase isozymes.  Journal Articles
• Quiescence-dependent activation of the p20K promoter in growth-arrested chicken embryo fibroblasts.  Journal Articles
• RELATIVE REPAIR OF ADENOVIRUS DAMAGED BY SUNLAMP, UV AND γ‐IRRADIATION IN COCKAYNE SYNDROME FIBROBLASTS IS DIFFERENT FROM THAT IN XERODERMA PIGMENTOSUM FIBROBLASTS  Journal Articles
• Rearrangement of human cell homologous chromosome domains in response to ionizing radiation  Journal Articles
• Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity  Journal Articles
• Reconstitution of Wild-Type or Mutant Telomerase Activity in Telomerase-Negative Immortal Human Cells  Journal Articles
• Redox-Induced Src Kinase and Caveolin-1 Signaling in TGF-β1-Initiated SMAD2/3 Activation and PAI-1 Expression  Journal Articles
• Reduced host cell reactivation of oxidatively damaged DNA in ageing human fibroblasts  Journal Articles
• Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3  Journal Articles
• Regulation of tissue inhibitor of metalloproteinase-1 in fibroblasts and acute phase proteins in hepatocytes in vitro by mouse oncostatin M, cardiotrophin-1, and IL-6.  Journal Articles
• Removal of UV photoproducts from an adenovirus-encoded reporter gene following infection of unirradiated and UV-irradiated human fibroblasts.  Journal Articles
• Repair phenotype in corneal fibroblasts is controlled by an interleukin-1 alpha autocrine feedback loop.  Journal Articles
• Replication of Subgenomic Hepatitis C Virus Replicons in Mouse Fibroblasts Is Facilitated by Deletion of Interferon Regulatory Factor 3 and Expression of Liver-Specific MicroRNA 122  Journal Articles
• Repopulation of ?0 cells with mitochondria from a patient with a mitochondrial DNA point mutation in tRNAGly results in respiratory chain dysfunction  Journal Articles
• Roberts syndrome fibroblasts showing cisplatin hypersensitivity have normal host cell reactivation of cisplatin-treated adenovirus and normal capacity of cisplatin-treated cells for adenovirus DNA synthesis  Journal Articles
• Role for Retinoblastoma Protein Family Members in UV-enhanced Expression from the Human Cytomegalovirus Immediate Early Promoter¶  Journal Articles
• Role of Human Antigen R (HuR) in the Regulation of Pulmonary ACE2 Expression  Journal Articles
• Role of Serum Amyloid A as an Intermediate in the IL-1 and PMA-Stimulated Signaling Pathways Regulating Expression of Rabbit Fibroblast Collagenase  Journal Articles
• Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis  Journal Articles
• Screening for genetic predisposition to mutagens in cancer patients  Journal Articles
• Selective cytotoxicity of gemcitabine in bladder cancer cell lines  Journal Articles
• Selective regulation of metalloproteinase inhibitor (TIMP-1) by oncostatin M in fibroblasts in culture.  Journal Articles
• Selective reovirus killing of bladder cancer in a co-culture spheroid model  Journal Articles
• Senescence of cultured human diploid fibroblasts. Are mutations responsible?  Journal Articles
• Sensitization of human melanoma cells by tamoxifen to apoptosis induction by pancratistatin, a nongenotoxic natural compound  Journal Articles
• Shining light on the significance of NK cell CD56 brightness  Journal Articles
• Sialidase-mediated depletion of GM2 ganglioside in Tay-Sachs neuroglia cells  Journal Articles
• Smad3 Null Mice Develop Airspace Enlargement and Are Resistant to TGF-β-Mediated Pulmonary Fibrosis  Journal Articles
• Smith–Lemli–Opitz syndrome with a classical phenotype, oesophageal achalasia and borderline plasma sterol concentrations  Journal Articles
• Somatic Gene Therapy for a Neurodegenerative Disease Using Microencapsulated Recombinant Cells  Journal Articles
• Somatic cell hybridization of Roberts syndrome and normal human fibroblasts transfected with plasmids carrying dominant selection markers  Journal Articles
• Somatic transcriptome priming gates lineage-specific differentiation potential of human-induced pluripotent stem cell states  Journal Articles
• Specific inhibition of beta-tryptase expression in a human mast cell line by granulocyte-macrophage colony-stimulating factor produced by airways structural cells.  Journal Articles
• SpontaneousIn VitroRelease of Alveolar-Macrophage Cytokines after the Intratracheal Instillation of Bleomycin in Rats: Characterization and Kinetic Studies  Journal Articles
• Stem cell factor in nasal polyposis and allergic rhinitis: Increased expression by structural cells is suppressed by in vivo topical corticosteroids  Journal Articles
• Studies on the ultraviolet light sensitivity of Bloom's syndrome fibroblasts  Journal Articles
• Suppression of immunological response against a novel gene product delivered by implants of genetically modified fibroblasts.  Journal Articles
• Sustained activation of the extracellular signal-regulated kinase pathway protects cells from photofrin-mediated photodynamic therapy.  Journal Articles
• TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease  Journal Articles
• TGF-β1 gene transfer to the mouse colon leads to intestinal fibrosis  Journal Articles
• THE LYON HYPOTHESIS  Journal Articles
• TRIM33 prevents pulmonary fibrosis by impairing TGF-β1 signalling  Journal Articles
• TRPV4 Stimulation Releases ATP via Pannexin Channels in Human Pulmonary Fibroblasts  Journal Articles
• TWIST1 DNA methylation is a cell marker of airway and parenchymal lung fibroblasts that are differentially methylated in asthma  Journal Articles
• Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs OXPHOS and prostate cancer metastatic spread  Journal Articles
• Telomerase activity in normal leukocytes and in hematologic malignancies  Journal Articles
• Telomere length predicts replicative capacity of human fibroblasts.  Journal Articles
• Telomere-dependent senescence  Journal Articles
• The CGL1 (HeLa × Normal Skin Fibroblast) Human Hybrid Cell Line: A History of Ionizing Radiation Induced Effects on Neoplastic Transformation and Novel Future Directions in SNOLAB  Journal Articles
• The IFN-Independent Response to Virus Particle Entry Provides a First Line of Antiviral Defense That Is Independent of TLRs and Retinoic Acid-Inducible Gene I  Journal Articles
• The Insulin-Mimetic Agent Vanadate Promotes Receptor Endocytosis and Inhibits Intracellular Ligand-Receptor Degradation by a Mechanism Distinct From the Lysosomotropic Agents  Journal Articles
• The Nitric Oxide Pathway Provides Innate Antiviral Protection in Conjunction with the Type I Interferon Pathway in Fibroblasts  Journal Articles
• The Role of Serotonin during Skin Healing in Post-Thermal Injury  Journal Articles
• The Role of the Lymphocyte in Haemopoiesis  Journal Articles
• The Role of the p53 Tumor Suppressor in the Response of Human Cells to Photofrin-mediated Photodynamic Therapy  Journal Articles
• The action of AF 2 on cultured hamster and human cells under aerobic and hypoxic conditions  Journal Articles
• The aryl hydrocarbon receptor suppresses cigarette-smoke-induced oxidative stress in association with dioxin response element (DRE)-independent regulation of sulfiredoxin 1  Journal Articles
• The constitutive activation of the CEF-4/9E3 chemokine gene depends on C/EBPβ in v-src transformed chicken embryo fibroblasts  Journal Articles
• The expression of matrix metalloproteinases and their inhibitors by pig synovial cells and their regulation by combinations of cytokines and growth factors  Journal Articles
• The human arylsulfatase-C isoenzymes: two distinct genes that escape from X inactivation.  Journal Articles
• The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults  Journal Articles
• The small heat‐shock protein αB‐crystallin is essential for the nuclear localization of Smad4: impact on pulmonary fibrosis  Journal Articles
• The therapeutic potential of pharmacological chaperones and proteosomal inhibitors, Celastrol and MG132 in the treatment of sialidosis  Journal Articles
• Therapeutic strategies to target connective tissue growth factor in fibrotic lung diseases  Journal Articles
• Tissue chondrification and ossification in keloids with primary report of five cases  Journal Articles
• Total synthesis of the cyanobacterial metabolite nostodione A: discovery of its antiparasitic activity against Toxoplasma gondii  Journal Articles
• Transcriptional activation of the CEF-4/9E3 cytokine gene by pp60v-src.  Journal Articles
• Transcriptomic profiling of gamma ray induced mutants from the CGL1 human hybrid cell system reveals novel insights into the mechanisms of radiation-induced carcinogenesis  Journal Articles
• Transduction of Human Bone Marrow by Adenoviral Vector  Journal Articles
• Transfer of Tumor Necrosis Factor-α to Rat Lung Induces Severe Pulmonary Inflammation and Patchy Interstitial Fibrogenesis with Induction of Transforming Growth Factor-β1 and Myofibroblasts  Journal Articles
• Transformation of human cultured fibroblasts with plasmids carrying dominant selection markers and immortalizing potential  Journal Articles
• Transforming Growth Factor-β Gene Transfer to the Lung Induces Myofibroblast Presence and Pulmonary Fibrosis  Conferences
• Transforming Growth Factor–β Evokes Ca²⁺ Waves and Enhances Gene Expression in Human Pulmonary Fibroblasts  Journal Articles
• Transient Overexpression of Gremlin Results in Epithelial Activation and Reversible Fibrosis in Rat Lungs  Journal Articles
• Treating IPF—all or nothing? A PRO‐CON debate  Journal Articles
• Treatment of a Lysosomal Storage Disease, Mucopolysaccharidosis VII, with Microencapsulated Recombinant Cells  Journal Articles
• Truncating Mutations in UBAP1 Cause Hereditary Spastic Paraplegia  Journal Articles
• Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP  Journal Articles
• Tunable degradation of low-fouling carboxybetaine-hyaluronic acid hydrogels for applications in cell encapsulation  Journal Articles
• Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia  Journal Articles
• U.V. Enhanced Reactivation of U.V.- and γ-irradiated Adenovirus in Cockayne Syndrome and Xeroderma Pigmentosum Fibroblasts  Journal Articles
• U.V. Enhanced Reactivation of U.V.- and γ-irradiated Adenovirus in Normal Human Fibroblasts  Journal Articles
• UV-enhanced Expression of a Reporter Gene is Induced at Lower UV Fluences in Transcription-coupled Repair Deficient Compared to Normal Human Fibroblasts, and is Absent in SV40-transformed Counterparts¶  Journal Articles
• UV-enhanced reactivation of a UV-damaged reporter gene suggests transcription-coupled repair is UV-inducible in human cells  Journal Articles
• Ultrastructural and immunocytochemical study of skin fibroblasts from normal and sialidosis patients  Journal Articles
• Ultrastructural pathology of the myocardium.  Journal Articles
• VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats  Journal Articles
• Valproate Attenuates Accelerated Atherosclerosis in Hyperglycemic ApoE-Deficient Mice  Journal Articles
• Variable clinical presentation in patients with defective E1 component of pyruvate dehydrogenase complex  Journal Articles
• Vascular–Parenchymal Cross-Talk Promotes Lung Fibrosis through BMPR2 Signaling  Conferences
• Water-soluble formulation of Coenzyme Q10 inhibits Bax-induced destabilization of mitochondria in mammalian cells  Journal Articles
• Xeroderma pigmentosum d-hela hybrids with low and high ultraviolet sensitivity associated with normal and diminished dna repair ability, respectively  Journal Articles
• [Autocrine activation of fibroblasts following irradiation].  Journal Articles
• γ-Ray enhanced reactivation of γ-irradiated adenovirus in human cells  Journal Articles
• γ-ray-enhanced reactivation of UV-irradiated adenovirus in normal human fibroblasts  Journal Articles
• δEF1 repressor controls selectively p53 family members during differentiation  Journal Articles