Journal article
Development of small alginate microcapsules for recombinant gene product delivery to the rodent brain
Abstract
A novel form of gene therapy using encapsulated recombinant cells in alginate microcapsules has proven effective in treating several animal models of human diseases. For treating neurological deficits in rodents with this technology, the size of the microcapsules has to be reduced for implantation in the central nervous system (CNS) to bypass the blood-brain barrier. This article reports the development of small alginate microcapsules suitable …
Authors
Ross CJD; Chang PL
Journal
Journal of Biomaterials Science Polymer Edition, Vol. 13, No. 8, pp. 953–962
Publisher
Taylor & Francis
Publication Date
1 2002
DOI
10.1163/156856202320401988
ISSN
0920-5063