Journal article
Calcium antagonistic actions of tetrandrine depend on cell types.
Abstract
We examined the effects of tetrandrine (TET) on Ca2+ mobilization in various types of cells using inositol trisphosphate-generating drugs and compared it with those using the microsomal Ca(2+)-ATPase inhibitor thapsigargin (TG) which is a tool for analyzing Ca2+ store-regulated Ca2+ entry (capacitative Ca2+ entry). In rat pheochromocytoma PC12 cells, 100 microM TET abolished high K+ (30 mM)-induced sustained increase in [Ca2+]i and partially …
Authors
Takemura H; Kwan CY; Ohshika H
Journal
Research Communications in Molecular Pathology and Pharmacology, Vol. 90, No. 1, pp. 59–68
Publication Date
October 1995
ISSN
1078-0297