Journal article
Ultrastructural and immunocytochemical study of skin fibroblasts from normal and sialidosis patients
Abstract
The objectives of this study were to analyze morphologically, morphometrically and immunocytochemically the lysosomal compartment of normal fibroblasts and of fibroblasts with neuraminidase deficiency. The immunocytochemical analyses consisted of quantifying the distribution of saposins and β-galactosidase in the lysosomes of these cells to test the hypothesis that neuraminisdase deficiency is associated with an impairment in the transport of …
Authors
Igdoura S; Morales C; Tranchemontagne J; Potier M
Journal
Cell and Tissue Research, Vol. 278, No. 3, pp. 527–534
Publisher
Springer Nature
Publication Date
12 1994
DOI
10.1007/bf00331370
ISSN
0302-766X