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An investigation into the effect of amphiphilic...
Journal article

An investigation into the effect of amphiphilic siloxane oligomers on dermal fibroblasts

Abstract

This study investigates the effect of well-defined poly(dimethylsiloxane)-poly(ethylene glycol) (PDMS-PEG) ABA linear block co-oligomers on the proliferation of human dermal fibroblasts. The co-oligomers assessed ranged in molecular weight (MW) from 1335 to 5208 Da and hydrophilic-lipophilic balance (HLB) from 5.9 to 16.6 by varying the number of both PDMS and PEG units. In general, it was found that co-oligomers of low MW or intermediate …

Authors

Farrugia BL; Keddie DJ; George GA; Lynam EC; Brook MA; Upton Z; Dargaville TR

Journal

Journal of Biomedical Materials Research Part A, Vol. 100A, No. 7, pp. 1919–1927

Publisher

Wiley

Publication Date

7 2012

DOI

10.1002/jbm.a.33310

ISSN

1549-3296