Journal article
Decreased repair of gamma ray damaged DNA in progeria
Abstract
A sensitive host-cell reactivation technique was used to examine the DNA repair ability of fibroblasts from two patients with classical progeria. Fibroblasts were infected with either non-irradiated or gamma-irradiated adenovirus type 2 and at 48 hrs after infection cells were examined for the presence of viral structural antigens using immunofluorescent staining. The production of viral structural antigens was considerably reduced in the …
Authors
Rainbow AJ; Howes M
Journal
Biochemical and Biophysical Research Communications, Vol. 74, No. 2, pp. 714–719
Publisher
Elsevier
Publication Date
January 1977
DOI
10.1016/0006-291x(77)90361-8
ISSN
0006-291X