Journal article
Extracellular Matrix and Fibrocyte Accumulation in BALB/c Mouse Lung upon Transient Overexpression of Oncostatin M
Abstract
The accumulation of extracellular matrix in lung diseases involves numerous factors, including cytokines and chemokines that participate in cell activation in lung tissues and the circulation of fibrocytes that contribute to local fibrotic responses. The transient overexpression of the gp130 cytokine Oncostatin M can induce extracellular matrix (ECM) accumulation in mouse lungs, and here, we assess a role for IL-13 in this activity using gene …
Authors
Botelho FM; Rodrigues R; Guerette J; Wong S; Fritz DK; Richards CD
Journal
Cells, Vol. 8, No. 2,
Publisher
MDPI
DOI
10.3390/cells8020126
ISSN
2073-4409