Journal article
Chromosome content and ultrastructure of radiation-induced micronuclei
Abstract
Unrepaired or misrepaired radiation damage in mammalian chromosomes can result in micronucleus formation at the first cell division. This represents loss of genomic information which may cause cell death. To improve our understanding of the mechanism of radiation-induced micronucleus formation, we characterized micronucleus ultrastructure and identified the origin of micronucleus DNA. Immunofluorescence microscopy showed that micronuclei were …
Authors
Walker J-A; Boreham DR; Unrau P; Duncan AMV
Journal
Mutagenesis, Vol. 11, No. 5, pp. 419–424
Publisher
Oxford University Press (OUP)
Publication Date
1996
DOI
10.1093/mutage/11.5.419
ISSN
0267-8357