Journal article
Role for Retinoblastoma Protein Family Members in UV‐enhanced Expression from the Human Cytomegalovirus Immediate Early Promoter¶
Abstract
The expression from a reporter construct driven by a cytomegalovirus (CMV) immediate early (IE) promoter is strongly inducible by UV in human fibroblasts. This response is induced at lower UV fluences in transcription‐coupled repair (TCR)–deficient fibroblasts compared with normal fibroblasts and is absent in their simian virus 40–transformed counterparts. In this study we demonstrate that expression of human papilloma virus (HPV) E7 (but not …
Authors
Francis MA; Rainbow AJ
Journal
Photochemistry and Photobiology, Vol. 77, No. 6, pp. 621–627
Publisher
American Society for Photobiology
DOI
10.1562/0031-8655(2003)0770621rfrpfm2.0.co2
ISSN
0031-8655
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AnimalsCytomegalovirusFibroblastsGene DeletionGene Expression Regulation, ViralGenes, Immediate-EarlyGenes, ReporterHumansMiceNuclear ProteinsOncogene Proteins, ViralPapillomaviridaePromoter Regions, GeneticRetinoblastoma ProteinRetinoblastoma-Like Protein p107Tumor Suppressor Protein p53Ultraviolet RaysXeroderma Pigmentosum