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Effect of histamine on proliferation of normal...
Journal article

Effect of histamine on proliferation of normal human adult lung fibroblasts.

Abstract

Fibrotic lung tissue shows increased connective tissue deposition and fibroblast proliferation and in addition a substantial increase in mast cell numbers in and around the fibrotic area. To elucidate the question of whether products of mast cells affect the proliferative behaviour of structural cells in the lung and thereby contribute to fibrogenesis, the effect of histamine, a prominent mast cell derived mediator, on the in vitro …

Authors

Jordana M; Befus AD; Newhouse MT; Bienenstock J; Gauldie J

Journal

Thorax, Vol. 43, No. 7,

Publisher

BMJ

Publication Date

July 1, 1988

DOI

10.1136/thx.43.7.552

ISSN

0040-6376