Clinical Trials as Topic
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subject area of
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Academic Article
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"Therapeutic range" for oral anticoagulant therapy. Academic Article
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236th ENMC International Workshop Bone protective therapy in Duchenne muscular dystrophy: Determining the feasibility and standards of clinical trials Hoofddorp, The Netherlands, 1–3 June 2018 Academic Article
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24-hour intragastric acidity and nocturnal acid secretion in patients with duodenal ulcer during oral administration of cimetidine and atropine. Academic Article
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Helicobacter pyloriEradication: A Critical Appraisal and Current Concerns Academic Article
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A 35-year journey to evidence-based medicine: a personal story Academic Article
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A Bayesian adaptive design for clinical trials of rare efficacy outcomes with multiple definitions Academic Article
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A Comparative Randomized Trial of Low-Dose Versus High-Dose Streptokinase in Deep Vein Thrombosis of the Thigh Academic Article
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A Comparison of Two Bias-Corrected Covariance Estimators for Generalized Estimating Equations Academic Article
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A Comparison of Zomepirac and Codeine as Analgesic Premedicants in Short-stay Surgery Academic Article
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A Consensus Development Approach to Define National Research Priorities in Bone Metastases: Proceedings from NCIC CTG Workshop Academic Article
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A Controlled Trial of Ambroxol in Chronic Bronchitis Academic Article
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A Double-Blind Crossover Study of Cinromide Versus Placebo in Epileptic Outpatients with Partial Seizures Academic Article
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A Large Trial Is Vital to Prove Perioperative β-blockade Effectiveness and Safety before Widespread Use Academic Article
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A Meta-analysis of the Studies of Dihydroergotamine plus Heparin in the Prophylaxis of Deep Vein Thrombosis Academic Article
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A Phase II Study of PF-03446962 in Patients with Advanced Malignant Pleural Mesothelioma. CCTG Trial IND.207 Academic Article
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A Practical Guide to Research: Design, Execution, and Publication Academic Article
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A Randomized Clinical Trial of the Leboyer Approach to Childbirth Academic Article
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A Randomized Controlled Trial of a Low-Molecular-Weight Heparin (Enoxaparin) to Prevent Deep-Vein Thrombosis in Patients Undergoing Elective Hip Surgery Academic Article
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A Systematic Review and Canadian Consensus Recommendations on the Use of Biomarkers in the Treatment of Non-small Cell Lung Cancer Academic Article
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A Systematic Review and Meta-Analyses of Nonsucrose Sweet Solutions for Pain Relief in Neonates Academic Article
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A Systematic Review and Meta-Analysis Evaluating the Efficacy of a Gluten-Free Diet and a Low FODMAPS Diet in Treating Symptoms of Irritable Bowel Syndrome Academic Article
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A Time-Trend Economic Analysis of Cancer Drug Trials Academic Article
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A call for consensus in defining efficacy in clinical trials for opioid addiction: combined results from a systematic review and qualitative study in patients receiving pharmacological assisted therapy for opioid use disorder Academic Article
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A clinician's guide for conducting randomized trials in individual patients. Academic Article
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A closer look at the distribution of number needed to treat (NNT): a Bayesian approach Academic Article
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A comparative study of continuous and intermittent epidural analgesia for labour and delivery Academic Article
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A comparison of Golytely and standard preparation for barium enema Academic Article
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A comparison of Likert and visual analogue scales for measuring change in function Academic Article
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A comparison of community and occupationally provided antihypertensive care. Academic Article
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A controlled trial of digoxin in congestive heart failure Academic Article
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A cost-effectiveness analysis of alternative approaches for long-term treatment of proximal venous thrombosis Academic Article
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A critical review of the evidence supporting a relationship between impaired fibrinolytic activity and venous thromboembolism Academic Article
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A double blind placebo controlled crossover randomized trial of diltiazem in Raynaud's phenomenon. Academic Article
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A double-blind comparison of ketotifen and disodium cromoglycate in atopic adult asthmatics Academic Article
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A double-blind randomized study comparing different dose regimens of H2-receptor antagonists on 24-hour gastric secretion in normal subjects and duodenal ulcer patients. Academic Article
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A framework for clinical evaluation of diagnostic technologies. Academic Article
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A large number of COVID-19 interventional clinical trials were registered soon after the pandemic onset: a descriptive analysis Academic Article
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A measure of quality of life for clinical trials in chronic lung disease. Academic Article
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A meta-analysis of the therapeutic role of oil soluble contrast media at hysterosalpingography: a surprising result? Academic Article
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A multi-centre clinical evaluation of isoflurane Academic Article
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A multicenter comparative trial of tobramycin and ticarcillin vs moxalactam and ticarcillin in febrile neutropenic patients Academic Article
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A multicentre prospective randomized trial comparing ceftazidime with cefazolin/tobramycin in the treatment of hospitalized patients with non-pneumococcal pneumonia Academic Article
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A multidisciplinary “think tank”: the top 10 clinical trial opportunities in transfusion medicine from the National Heart, Lung, and Blood Institute-sponsored 2009 state-of-the-science symposium Academic Article
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A new era in idiopathic pulmonary fibrosis: considerations for future clinical trials Academic Article
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A new measure of health status for clinical trials in inflammatory bowel disease Academic Article
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A new perspective on concepts of asthma severity and control Academic Article
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A new respiratory fluoroquinolone, oral gemifloxacin: a safety profile in context Academic Article
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A novel lung disease phenotype adjusted for mortality attrition for cystic fibrosis Genetic modifier studies Academic Article
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A phase II study of bortezomib and gemcitabine in relapsed mantle cell lymphoma from the National Cancer Institute of Canada Clinical Trials Group (IND 172) Academic Article
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A placebo-controlled study to determine the efficacy of oral disopyramide phosphate for the prophylaxis of ventricular dysrhythmias after acute myocardial infarction. Academic Article
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A probabilistic cost-effectiveness analysis of enoxaparin versus unfractionated heparin for the prophylaxis of deep-vein thrombosis following major trauma. Academic Article
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A qualitative study evaluating causality attribution for serious adverse events during early phase oncology clinical trials Academic Article
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A randomized trial of less intense postoperative warfarin or aspirin therapy in the prevention of venous thromboembolism after surgery for fractured hip Academic Article
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A randomized trial of maintenance versus no maintenance melphalan and prednisone in responding multiple myeloma patients Academic Article
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A real-time dashboard of clinical trials for COVID-19 Academic Article
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A response to–There’s madness in their methods Academic Article
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A review of body mass index and waist circumference as markers of obesity and coronary heart disease risk in persons with chronic spinal cord injury Academic Article
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A review of valproate in psychiatric practice Academic Article
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A secondary prevention, randomized trial of suloctidil in patients with a recent history of thromboembolic stroke. Academic Article
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A short note on probability in clinical medicine Academic Article
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A small p-value from an observed data is not evidence of adequate power for future similar-sized studies: A cautionary note Academic Article
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A stochastic model for survival of early prostate cancer with adjustments for leadtime, length bias, and over‐detection Academic Article
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A systematic overview of the effectiveness of home visiting as a delivery strategy for public health nursing interventions. Academic Article
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A systematic review of comparisons between protocols or registrations and full reports in primary biomedical research Academic Article
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A systematic review of integrative clinical trials for supportive care in pediatric oncology: a report from the International Society of Pediatric Oncology, T&CM collaborative Academic Article
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A systematic review of medication safety and clinical outcomes related to drug interaction software. Academic Article
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A systematic review of symptomatic outcomes used in oesophagitis drug therapy trials Academic Article
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A tool for assessing the comprehensiveness of outcome reporting within clinical trials in pregnancy Academic Article
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A tutorial on sensitivity analyses in clinical trials: the what, why, when and how Academic Article
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ACUTE VINCRISTINE NEUROTOXICITY Academic Article
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AHA Conference Report on Cholesterol. Intervention studies. Academic Article
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ANTIPLATELET AGENTS: THEIR ROLE IN THE PREVENTION OF SUDDEN DEATH Academic Article
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APPLICATION OF THE CONSOLIDATED STANDARDS OF REPORTING TRIALS (CONSORT) IN THE FRACTURE CARE LITERATURE Academic Article
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AUSTRALIAN MULTICENTRE TRIAL OF STREPTOKINASE IN ACUTE MYOCARDIAL INFARCTION Academic Article
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AZATHIOPRINE AND PREDNISONE IN THE TREATMENT OF ADULTS WITH LUPUS NEPHRITIS Academic Article
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Absorption and antidysrhythmic activity of oral disopyramide phosphate after acute myocardial infarction. Academic Article
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Accelerating Clinical Evaluation of Repurposed Combination Therapies for COVID-19 Academic Article
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Accuracy of screening women at familial risk of breast cancer without a known gene mutation: Individual patient data meta-analysis Academic Article
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Achieving remission in clinical practice: lessons from clinical trial data. Academic Article
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Acid suppression in duodenal ulcer: a meta-analysis to define optimal dosing with antisecretory drugs. Academic Article
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Acupuncture as an Evidence-Based Option for Symptom Control in Cancer Patients Academic Article
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Acupuncture for Neck Disorders Academic Article
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Acute Ischemic Stroke Therapy Overview Academic Article
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Acute effects of oral pyridostigmine on memory and cognitive function in SDAT Academic Article
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Acute myelogenous leukemia in adolescents and young adults Academic Article
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Acute response to bronchodilator. An imperfect guide for bronchodilator therapy in chronic airflow limitation Academic Article
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Adapting the Lung Cancer Symptom Scale(LCSS) to mesothelioma Academic Article
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Adaptive platform trials: definition, design, conduct and reporting considerations Academic Article
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Addressing dichotomous data for participants excluded from trial analysis: a guide for systematic reviewers Academic Article
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Addressing the Unit of Analysis in Medical Care Studies Academic Article
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Adjudicating Outcomes: Fundamentals Academic Article
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Adjunctive antiarrhythmic drug therapy in patients with implantable cardioverter defibrillators: a systematic review Academic Article
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Adjusted Subcutaneous Heparin or Continuous Intravenous Heparin in Patients with Acute Deep Vein Thrombosis Academic Article
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Adjusted Subcutaneous Heparin versus Warfarin Sodium in the Long-Term Treatment of Venous Thrombosis Academic Article
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Adjuvant endocrine therapies for pre-/perimenopausal women Academic Article
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Adjuvant targeted therapy in early breast cancer Academic Article
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Adjuvant therapy for resected non-small-cell lung cancer: Past, present, and future Academic Article
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Adjuvant/neoadjuvant trastuzumab therapy in women with HER-2/neu-overexpressing breast cancer: A systematic review Academic Article
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Advances in Antithrombotic Therapy Academic Article
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Advances in Antithrombotic Therapy: Novel Agents Academic Article
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Advances in the management of venous thromboembolism Academic Article
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Advances in the management of venous thromboembolism. Academic Article
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Advancing Academic Cancer Clinical Trials Recruitment in Canada Academic Article
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Adverse effects of β-agonists Academic Article
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Aerosol Therapy with Sch 1000 Academic Article
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Airway smooth muscle as a target of asthma therapy: history and new directions Academic Article
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Albumin in critical care: SAFE, but worth its salt? Academic Article
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Allergen immunotherapy with cat allergen peptides Academic Article
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Allergic Rhinitis and its Impact on Asthma (ARIA): Achievements in 10 years and future needs Academic Article
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Allogenic leukocyte immunization after five or more miscarriages. Recurrent Miscarriage Immunotherapy Trialists Group Academic Article
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American Heart Association/American College of Cardiology Foundation Guide to Warfarin Therapy Academic Article
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American college of rheumatology preliminary definition of improvement in rheumatoid arthritis Academic Article
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Amiodarone after myocardial infarction: EMIAT and CAMIAT trials. Academic Article
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Amoxycillin dual therapy against Helicobacter pylori--the final nail in the coffin? Academic Article
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An Evidence-Based Approach to the Adoption of New Technology Academic Article
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An Improved Definition of Immune Heparin-Induced Thrombocytopenia in Postoperative Orthopedic Patients Academic Article
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An Introduction to Multivariate Statistics Academic Article
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An N of 1 Service: Applying the Scientific Method in Clinical Practice Academic Article
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An Official American Thoracic Society Workshop Report: Translational Research in Rare Respiratory Diseases Conference Paper
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An Official American Thoracic Society/European Respiratory Society Statement: Asthma Control and Exacerbations Academic Article
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An electrophysiological study of Duchenne dystrophy Academic Article
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An evaluation of paroxetine in generalised social anxiety disorder Academic Article
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An overview of clinical trials of low molecular weight heparin fractions. Academic Article
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An overview of platform trials with a checklist for clinical readers Academic Article
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An overview of precision oncology basket and umbrella trials for clinicians Academic Article
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An overview of randomized trials of rehabilitation with exercise after myocardial infarction. Academic Article
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An overview of the GRADE approach and a peek at the future Academic Article
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An updated safety profile of moxifloxacin. Academic Article
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Analysis of Observational Studies: A Guide to Understanding Statistical Methods Academic Article
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Analysis of dose intensity for adjuvant chemotherapy trials in stage II breast cancer. Academic Article
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Analysis of dose intensity for chemotherapy in early (stage II) and advanced breast cancer. Academic Article
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Analyzing Oncology Clinical Trial Data Using the Q-TWiST Method: Clinical Importance and Sources for Health State Preference Data* Academic Article
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Angiotensin-receptor blockers in prevention of cardiovascular events: are they as effective as angiotensin-converting enzyme inhibitors? Academic Article
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Ankylosing spondylitis antirheumatic drug trials. I. Effects of standardization procedures on observer dependent outcome measures. Academic Article
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Ankylosing spondylitis antirheumatic drug trials. II. Tables for calculating sample size for clinical trials. Academic Article
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Ankylosing spondylitis antirheumatic drug trials. III. Setting the delta for clinical trials of antirheumatic drugs--results of a consensus development (Delphi) exercise. Academic Article
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Anti-TNFα therapy in immune-mediated subfertility: State of the art Academic Article
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Anti-ischaemic effects of ACE inhibitors: review of current clinical evidence and ongoing clinical trials. Academic Article
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Anti-thrombotic options for secondary prevention in patients with chronic atherosclerotic vascular disease: what does COMPASS add? Academic Article
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Antibiotics: A New Hope Academic Article
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Antibody and cellular therapies for treatment of covid-19: a living systematic review and network meta-analysis Academic Article
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Anticoagulant therapy for the thrombotic complications of the antiphospholipid antibody syndrome Conference Paper
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Anticoagulants in acute coronary syndromes Academic Article
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Anticoagulants in cancer Academic Article
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Anticoagulation for Atrial Fibrillation: State of the Art and Recommendations for a Quickly Moving Target Academic Article
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Anticoagulation for patients with atrial fibrillation and risk factors for stroke Academic Article
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Antioxidants in the prevention of human atherosclerosis. Summary of the proceedings of a National Heart, Lung, and Blood Institute Workshop: September 5-6, 1991, Bethesda, Maryland. Academic Article
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Antiphospholipid antibiodies: a critical review of the literature Academic Article
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Antithrombotic Agents Academic Article
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Antithrombotic Agents in Coronary Artery Disease Academic Article
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Antithrombotic Therapy for Cerebrovascular Disorders Academic Article
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Antithrombotic Therapy in Coronary Ischaemia: The Expanding Role of Low-Molecular-Weight Heparin Academic Article
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Antithrombotic Therapy in Patients With Mechanical and Biological Prosthetic Heart Valves Academic Article
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Antithrombotic Therapy in Patients With Saphenous Vein and Internal Mammary Artery Bypass Grafts Academic Article
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Antithrombotic drug removal from whole blood using Haemoadsorption with a porous polymer bead sorbent Academic Article
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Antithrombotic effects of drugs which suppress platelet function: their potential in prevention growth of tumour cells. Academic Article
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Antithrombotic therapy for stroke prevention in non-valvular atrial fibrillation Academic Article
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Antithrombotic therapy: the expanding role of low molecular weight heparin. Academic Article
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Análisis interino en ensayos clínicos: una guía metodológica Academic Article
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Application of Epidemiological Methodology to Sports ana Exercise Science Research Academic Article
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Application of the systematic review and bibliometric network analysis (SeBriNA) methodology contextualizes evidence. Part 2: rituximab for non-Hodgkin's lymphoma Academic Article
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Applied pharmacoeconomics: considerations to drive the choice of a prophylactic antithrombotic regimen Academic Article
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Applying the findings of clinical trials to individual patients Academic Article
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Appropriate outcome measures in trials evaluating treatment of atrial fibrillation Academic Article
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Are Large Fracture Trials Possible? Academic Article
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Are clinical trials randomising households to lifestyle interventions to delay cognitive decline feasible? A pilot study to determine the beliefs, preferences, and deterrents for households impacted by dementia based on semi-structured interviews Academic Article
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Are placebo‐controlled trials ethical in areas where current guidelines recommend therapy? No Academic Article
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Are quality of life, patient preferences, and costs realistic outcomes for clinical trials? Academic Article
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Aromatase inhibitor therapy: toxicities and management strategies in the treatment of postmenopausal women with hormone-sensitive early breast cancer Academic Article
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Arteriovenous-Shunt Thrombosis Academic Article
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Aspiration thrombectomy in ST-elevation myocardial infarction Academic Article
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Aspirin Versus Low-Molecular-Weight Heparin for Ischemic Stroke in Children: An Unanswered Question Academic Article
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Aspirin and Other Platelet-Active Drugs Conference Paper
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Aspirin and other platelet-active drugs. The relationship among dose, effectiveness, and side effects. Academic Article
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Aspirin in the treatment of cardiovascular disease: A review Academic Article
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Aspirin, Sulfinpyrazone, or Both in Unstable Angina Academic Article
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Assay of human stem cells by repopulation of NOD/SCID mice Academic Article
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Assessing Clinical Significance in Measuring Oncology Patient Quality of Life: Introduction to the Symposium, Content Overview, and Definition of Terms Academic Article
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Assessing sensitivity to change: choosing the appropriate change coefficient Academic Article
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Assessing the Methodological Quality of Nonrandomized Intervention Studies Academic Article
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Assessment and Treatment of Social Phobia Academic Article
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Assessment of quality of life in adolescents with allergic rhinoconjunctivitis: Development and testing of a questionnaire for clinical trials Academic Article
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Association between asymptomatic deep vein thrombosis detected by venography and symptomatic venous thromboembolism in patients undergoing elective hip or knee surgery Academic Article
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Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis Academic Article
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Association between physicians’ interaction with pharmaceutical companies and their clinical practices: A systematic review and meta-analysis Academic Article
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Association of Factor V Leiden With Subsequent Atherothrombotic Events Academic Article
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Association of handgrip strength to cardiovascular mortality in pre-diabetic and diabetic patients: A subanalysis of the ORIGIN trial Academic Article
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Association of transdermal nitroglycerin to vasopressin infusion in the treatment of variceal hemorrhage: A placebo-controlled clinical trial Academic Article
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Asthma treatment: inhaled beta-agonists. Academic Article
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Attention to the principles of exercise training in exercise studies on prostate cancer survivors: a systematic review Academic Article
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Attitudes of Canadian Oncology Practitioners Toward Psychosocial Interventions in Clinical and Research Settings in Women With Breast Cancer Academic Article
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Auranofin therapy and quality of life in patients with rheumatoid arthritis. Results of a multicenter trial Academic Article
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Auricular acupuncture for analgesia after arthroscopy Academic Article
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Barriers and Facilitating Factors for Conducting Systematic Evidence Assessments in Academic Clinical Trials Academic Article
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Barriers to participation in HIV drug trials: a systematic review Academic Article
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Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors Academic Article
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Basic statistics for clinicians: 1. Hypothesis testing. Academic Article
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Basic statistics for clinicians: 2. Interpreting study results: confidence intervals. Academic Article
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Benefit of Selective Factor Inhibition Academic Article
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Beta blockade during and after myocardial infarction: An overview of the randomized trials Academic Article
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Beta-blocker therapy for congestive heart failure: a systemic overview and critical appraisal of the published trials. Academic Article
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Beta-blockers in immediate treatment of myocardial infarction Academic Article
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Better Treatments That Cost More: The Dilemma Academic Article
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Beyond Mortality Academic Article
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Beyond Survival: Pediatric Critical Care Interventional Trial Outcome Measure Preferences of Families and Healthcare Professionals* Academic Article
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Beyond Unfractionated Heparin and Warfarin Academic Article
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Beyond heparin and warfarin: the new generation of anticoagulants Academic Article
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Bias in dissemination of clinical research findings: structured OPEN framework of what, who and why, based on literature review and expert consensus Academic Article
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Bias in transfusion research: from study design to result reporting Academic Article
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Bilateral vs. ipsilateral venography as the primary efficacy outcome measure in thromboprophylaxis clinical trials: a systematic review Academic Article
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Bimekizumab: The First Dual Inhibitor of Interleukin (IL)-17A and IL-17F for the Treatment of Psoriatic Disease and Ankylosing Spondylitis Academic Article
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Biosimilars for psoriasis: clinical studies to determine similarity Academic Article
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Bleeding Complications in Patients with Acute Coronary Syndromes: Are They Important and How Can We Prevent Them? Academic Article
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Bleeding complications in immune thrombocytopenia Academic Article
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Blocking the renin–angiotensin system: dual- versus mono-therapy Academic Article
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Blood Pressure Targets For Vasopressor Therapy Academic Article
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Breaking up is Hard to Do: The Heartbreak of Dichotomizing Continuous Data Academic Article
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Breast cancer in a BRCA2 mutation carrier with a history of prostate cancer Academic Article
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Briakinumab Academic Article
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Bronchoconstriction Stimulated by Airway Cooling Academic Article
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Bronchodilator delivery in acute airflow obstruction. A meta-analysis Academic Article
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Building clinical trial priorities at the University of Rwanda Academic Article
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CANadian Network and Centre for Trials INternationally (CANNeCTIN): A national network for Canadian-led trials in cardiovascular diseases and diabetes mellitus Academic Article
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CLINICAL TRIALS OF PACING MODE SELECTION Academic Article
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COMMENTARY: Should Anti-TNF-α Therapy be Offered to Patients with Infertility and Recurrent Spontaneous Abortion?* Academic Article
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CONSORT extension for reporting N-of-1 trials (CENT) 2015 Statement Academic Article
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CONSORT extension for reporting N-of-1 trials (CENT) 2015: explanation and elaboration Academic Article
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CTS: A clinical trials simulator Academic Article
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Calcium and Vitamin D Therapy in Corticosteroid-Induced Bone Loss: What is the Evidence? Conference Paper
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Can it work? Does it work? Is it worth it? Academic Article
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Can orthopedic trials change practice? Academic Article
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Can severity of symptoms be used as an outcome measure in trials of non-ulcer dyspepsia and helicobacter pylori associated gastritis? Academic Article
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Can simple clinical measurements detect patient noncompliance? Academic Article
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Can we differentiate the low-molecular-weight heparins? Academic Article
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Canadian Cardiovascular Society Consensus Conference guidelines on heart failure, update 2009: Diagnosis and management of right-sided heart failure, myocarditis, device therapy and recent important clinical trials Academic Article
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Canadian Guidelines for the Management of Acute Exacerbations of Chronic Bronchitis Academic Article
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Canadian Red Cross Society Symposium on Leukodepletion: Report of Proceedings Academic Article
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Canadian-led capacity-building in biostatistics and methodology in cardiovascular and diabetes trials: the CANNeCTIN Biostatistics and Methodological Innovation Working Group Academic Article
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Cancer surveillance and control in adolescents—similarities and contrasts between Canada and the United States Academic Article
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Candesartan for the management of heart failure: more than an alternative Academic Article
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Carbenoxolone sodium in the treatment of gastric ulcer with special reference to side-effects. Academic Article
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Cardioembolic Stroke Academic Article
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Cardiovascular Health and Aromatase Inhibitors Academic Article
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Cardiovascular Risk in Patients with Early Renal Insufficiency Academic Article
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Cardiovascular Safety Of Nintedanib In Subgroups By Cardiovascular Risk At Baseline In The Tomorrow And Inpulsis Trials Conference Paper
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Cardiovascular events in chronic myeloid leukemia clinical trials. Is it time to reassess and report the events according to cardiology guidelines? Academic Article
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Cardiovascular outcome trials in patients with chronic kidney disease: challenges associated with selection of patients and endpoints Academic Article
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Care models in the management of haemophilia: a systematic review Academic Article
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Carotid endarterectomy: three critical evaluations. North American Symptomatic Carotid Endarterectomy Study Group. Academic Article
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Carotid plaque formation and its evaluation with angiography, ultrasound, and MR angiography Academic Article
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Carryover and the Two-Period Crossover Clinical Trial Academic Article
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Cell encapsulation: Promise and progress Academic Article
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Central statistical monitoring: Detecting fraud in clinical trials Academic Article
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Cervical repening and labor induction with prostaglandin E2 gel: A placebo-controlled study Academic Article
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Challenges in Systematic Reviews That Evaluate Drug Efficacy or Effectiveness Academic Article
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Challenges in conducting clinical trials in nephrology: conclusions from a Kidney Disease—Improving Global Outcomes (KDIGO) Controversies Conference Academic Article
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Challenges in designing antirheumatic drug trials. Academic Article
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Challenges in evaluating surgical innovation Academic Article
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Challenges to complete and useful data sharing Academic Article
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Changes of Methodology in Clinical Trials of Sepsis Over Time Academic Article
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Characteristics that predicted recurrence of infarction within 3 years in the Ontario Exercise-Heart Collaborative Study. Academic Article
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Chemotherapy can prolong survival in patients with advanced non-small-cell lung cancer--report of a Canadian multicenter randomized trial. Academic Article
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Classification and appraisal of the level of clinical evidence of publications from the Canadian Association of Pediatric Surgeons for the past 10 years Academic Article
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Classification of the acute emetogenicity of chemotherapy in pediatric patients: A clinical practice guideline Academic Article
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Clinical Characteristics and Outcomes of Young and Very Young Adults With Heart Failure Academic Article
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Clinical Research: From Case Reports to International Multicenter Clinical Trials Academic Article
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Clinical Studies: Evidence for Intervention with Specific Antiplatelet Drugs in Arterial Thromboembolism Academic Article
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Clinical Trial Data Sharing for COVID-19–Related Research Academic Article
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Clinical Trial Design in Acute Lung Injury—Issues and Controversies Academic Article
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Clinical Trial Evidence Supporting US Food and Drug Administration Approval of Novel Cancer Therapies Between 2000 and 2016 Academic Article
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Clinical Trial Opportunities in Transfusion Medicine: Proceedings of a National Heart, Lung, and Blood Institute State-of-the-Science Symposium Academic Article
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Clinical Trial Registration in Physical Therapy Journals: Recommendations from the International Society of Physiotherapy Journal Editors Academic Article
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Clinical Trial Registration in Physiotherapy Journals: Recommendations From the International Society of Physiotherapy Journal Editors Academic Article
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Clinical Trials in Cognitively Impaired Older Adults: Home versus Clinic Assessments Academic Article
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Clinical Use of Low Molecular Weight Heparins and Heparinoids Academic Article
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Clinical application of the concept of methotrexate plus 5-FU sequence-dependent "synergy": how good is the evidence? Academic Article
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Clinical cooperative trials of the National Cancer Institute of Canada Clinical Trials Group Breast Cancer Site Group. Academic Article
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Clinical cooperative trials of the national cancer institute of Canada clinical trials group breast cancer site group Conference Paper
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Clinical efficacy and electrophysiology of oral propafenone for ventricular tachycardia Academic Article
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Clinical outcomes trials and the cardiovascular effects of thiazolidinediones: Implications for the evaluation of antidiabetic drugs Academic Article
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Clinical therapeutic trial of aspirin and azapropazone in rheumatoid arthritis when prescribed singly and in combination Academic Article
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Clinical trial design in adult reflux disease: a methodological workshop Academic Article
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Clinical trial of chorion biopsy. Academic Article
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Clinical trial of common treatments for low back pain in family practice. Academic Article
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Clinical trial of deglydyrrhizinized liquorice in gastric ulcer. Academic Article
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Clinical trial registration in physical therapy journals: recommendations from the International Society of Physiotherapy Journal Editors Academic Article
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Clinical trial registration in physiotherapy journals: Recommendations from the International Society of Physiotherapy Journal Editors Academic Article
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Clinical trial registration in physiotherapy journals: recommendations from the International Society of Physiotherapy Journal Editors Academic Article
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Clinical trial registration in physiotherapy journals: recommendations from the International Society of Physiotherapy Journal Editors Academic Article
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Clinical trial update: National Cancer Institute of Canada Academic Article
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Clinical trials and haemophilia: does the Bayesian approach make the ideal and desirable good friends? Academic Article
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Clinical trials as diagnostic tests Academic Article
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Clinical trials of disease stages in COVID 19: complicated and often misinterpreted Academic Article
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Clinical trials update from the European Society of Cardiology Meeting 2009: AAA, RELY, PROTECT, ACTIVE‐I, European CRT survey, German pre‐SCD II registry, and MADIT‐CRT Conference Paper
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Clinician-trialist rounds: 11. When your grant gets turned down – part 1: remorse, anger, and reconciliation Academic Article
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Clinician-trialist rounds: 24. Modernizing your introductory graduate course in clinical trials. Part 1: Commonsense meets evidence Academic Article
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Clinician-trialist rounds: 25. Designing an evidence-based introductory graduate course in clinical trials. Part 2: Applying the evidence to your RCT course design Academic Article
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Clopidogrel in acute coronary syndromes: Where are we now? Academic Article
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Clozapine and Psychosocial Function in Schizophrenia: A Systematic Review and Meta-Analysis Academic Article
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Colchicine for Secondary Prevention of Cardiovascular Disease Academic Article
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Collaborative cardiovascular clinical trials in Canada. The Canadian Cardiovascular Collaboration. Academic Article
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Colorectal surgery: short-term prophylaxis with aztreonam plus clindamycin versus gentamicin plus clindamycin. Academic Article
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Combination 13-cis-retinoic acid and interferon alpha-2a in the therapy of solid tumors. Academic Article
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Combining LABA and ICS in patients with severe COPD Academic Article
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Combining endocrine agents with chemotherapy: Which patients and what sequence? Conference Paper
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Comment on the effectiveness of induction of labor for postterm pregnancy Academic Article
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Commentary on Cox CL, Lensing S, Rai SN et al. Proxy assessment of quality of life in pediatric clinical trials: Application of the Health Utilities Index 3. Qual Life Res 2005; 14: 1045–1056 Academic Article
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Commentary on Jack Dowie, ?Decision validity should determine whether a genericor condition-specific HRQOL measure is used in health care decisions? Academic Article
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Commentary: The Once and Future Psychiatry Academic Article
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Comparative Therapeutic Studies with Tilavist Academic Article
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Comparative effectiveness and safety of the novel oral anticoagulants: do the pivotal clinical trials point to a new paradigm? Academic Article
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Comparative efficacy and safety of first-line antiretroviral therapy for the treatment of HIV infection: a systematic review and network meta-analysis Academic Article
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Comparative tolerability of treatments for acute migraine: A network meta-analysis Academic Article
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Comparative tolerability of two formulations of Rhinalar (flunisolide) nasal spray in patients with seasonal allergic rhinitis. Academic Article
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Comparison between Cytokine Concentration in Follicular Fluid of Poor and High Responder Patients and their Influence of ICSI-outcome Academic Article
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Comparison of 12 Risk Stratification Schemes to Predict Stroke in Patients With Nonvalvular Atrial Fibrillation Academic Article
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Comparison of Arthroplasty Trial Publications After Registration in ClinicalTrials.gov Academic Article
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Comparison of High-Dose with Low-Dose Subcutaneous Heparin to Prevent Left Ventricular Mural Thrombosis in Patients with Acute Transmural Anterior Myocardial Infarction Academic Article
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Comparison of published orthopaedic trauma trials following registration in Clinicaltrials.gov Academic Article
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Comparison of ranitidine and cimetidine maintenance treatment of duodenal ulcer. Academic Article
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Design and Rationale of Health-Related Quality of Life and Patient-Reported Outcomes Assessment in the Frequent Hemodialysis Network Trials Conference Paper
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Design and assessment of clinical trials on continuous infusion. Conference Paper
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Design, Conduct, and Interpretation of Nonrandomized Orthopaedic Studies: A Practical Approach Academic Article
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Design, analysis and reporting of multi-arm trials and strategies to address multiple testing Conference Paper
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Designing research in vulnerable populations: lessons from HIV prevention trials that stopped early Academic Article
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Diabetes clinical trials: helped or hindered by the current shift in regulatory requirements? Academic Article
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Diagnostic Efficacy of Impedance Plethysmography for Clinically Suspected Deep-Vein Thrombosis Academic Article
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Different Intensities of Oral Anticoagulant Therapy in the Treatment of Proximal-Vein Thrombosis Academic Article
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Differential power of placebo across major psychiatric disorders: a preliminary meta-analysis and machine learning study Academic Article
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Discrimination of changes in osteoporosis outcomes. Conference Paper
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Early Intravenous Beta-Blockade in Acute Myocardial Infarction Academic Article
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Early intravenous beta blockade in acute myocardial infarction. Academic Article
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Early stage ovarian cancer: a randomized clinical trial comparing whole abdominal radiotherapy, melphalan, and intraperitoneal chromic phosphate: a National Cancer Institute of Canada Clinical Trials Group report. Academic Article
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Echocardiographic evaluation of left ventricular function in patients showing an antihypertensive and biochemical response to indapamide. Academic Article
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Economic evaluation of nivolumab for the treatment of second-line advanced squamous NSCLC in Canada: a comparison of modeling approaches to estimate and extrapolate survival outcomes Academic Article
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Effect of Digoxin on Right Ventricular Function in Severe Chronic Airflow Obstruction Academic Article
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Effect of drug therapy on survival in chronic congestive heart failure Academic Article
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Effect of incretin-based therapies on cancers of digestive system among 101 595 patients with type 2 diabetes mellitus: a systematic review and network meta-analysis combining 84 trials with a median duration of 30 weeks Academic Article
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Efficacy of progesterone support in the luteal phase following in-vitro fertilization and embryo transfer: meta-analysis of clinical trials Academic Article
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Endocrine therapy of advanced disease: analysis and implications of the existing data. Academic Article
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Endocrine treatment-associated cognitive impairment in breast cancer survivors: evidence from published studies Academic Article
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Epidermal growth factor receptors and cyclooxygenase-2 in the pathogenesis of non-small cell lung cancer: potential targets for chemoprevention and systemic therapy Academic Article
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Epidural analgesia during labour. Academic Article
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Eradication of Helicobacter pylori infection in the management of patients with dyspepsia and non-ulcer dyspepsia. Academic Article
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Estimating per patient funding for cancer clinical trials: An Ontario based survey Academic Article
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Estimating the Power of Indirect Comparisons: A Simulation Study Academic Article
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Estimating the number needed to treat (NNT) index when the data are subject to error Academic Article
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Etretinate Blood Levels in Monitoring of Compliance and Contamination in a Chemoprevention Trial Academic Article
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Evaluation of Neonatal-Intensive-Care Programs Academic Article
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Evaluation of impairment of health related quality of life in asthma: development of a questionnaire for use in clinical trials. Academic Article
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Evaluation of intervention reporting in published emergency medicine clinical trials Academic Article
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Evaluation of the Effectiveness of Suicide Prevention Programs: A Methodological Perspective Academic Article
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Evaluation of the addition of cromolyn sodium to bronchodilator maintenance therapy in the long-term management of asthma Academic Article
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Event adjudication and data monitoring in an intensive care unit observational study of thromboprophylaxis Academic Article
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Evidence-Based Neonatal Drug Therapy for Prevention of Bronchopulmonary Dysplasia in Very-Low-Birth-Weight Infants Academic Article
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Evidence-based treatment of the antiphospholipid syndrome Academic Article
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Extension of anticoagulation after venous thromboembolism Academic Article
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FACE-Q scales for health-related quality of life, early life impact, satisfaction with outcomes, and decision to have treatment: development and validation. Academic Article
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FDA ovarian cancer clinical trial endpoints workshop: A Society of Gynecologic Oncology White Paper Academic Article
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Factor VIII concentrate for hemophilia: comparison of two heat-treated products. Academic Article
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Factor Xa and thrombin as targets for new oral anticoagulants Academic Article
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Factor Xa or thrombin: Is thrombin a better target? Conference Paper
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Factors influencing the quality of clinical trials on traditional Chinese medicine—Qualitative interviews with trial auditors, clinicians and academic researchers Academic Article
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Failure of Weight Reduction to Reduce Mildly Elevated Blood Pressure: A Randomized Trial Academic Article
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Favorable Pharmacokinetic Characteristics of Extended-Half-Life Recombinant Factor VIII BAY 94-9027 Enable Robust Individual Profiling Using a Population Pharmacokinetic Approach Academic Article
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Fibroblast Growth Factor (FGF), Intracellular Adhesion Molecule (sICAM-1) Level in Serum and Follicular Fluid of Infertile Women with Polycystic Ovarian Syndrome, Endometriosis and Tubal Damage, and their Effect on ICSI Outcome Academic Article
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Fluid Lavage of Open Wounds (FLOW): design and rationale for a large, multicenter collaborative 2 × 3 factorial trial of irrigating pressures and solutions in patients with open fractures Academic Article
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Focused 2012 Update of the Canadian Cardiovascular Society Guidelines for the Use of Antiplatelet Therapy Academic Article
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Folic Acid–Based Multivitamin Therapy to Prevent Stroke Academic Article
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Fondaparinux: a Factor Xa inhibitor for antithrombotic therapy Academic Article
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Frequency of administration of short half-life nonsteroidal anti-inflammatory analgesics (NSAID's): studies with ibuprofen. Academic Article
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Functional status changes following medical or surgical treatment for cerebral ischemia. Results of the extracranial-intracranial bypass study Academic Article
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Funding Oncology Clinical Trials: Are Cooperative Group Trials Sustainable? Academic Article
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Further conclusions from the extracranial-intracranial bypass trial Academic Article
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Gastric acidity and preneoplastic/neoplastic changes of the stomach. Academic Article
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Gene Therapy: Socioeconomic and Ethical Issues A Roundtable Discussion Academic Article
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Guidelines for osteoporosis trials. Academic Article
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Identification and Evaluation of Controlled Trials in Pediatric Cardiology: Crowdsourced Scoping Review and Creation of Accessible Searchable Database Academic Article
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Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology [see comments] Academic Article
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Imipenem: a new carbapenem. Committee on Antimicrobial Agents, Canadian Infectious Disease Society. Academic Article
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Immune checkpoint-inhibitors and chemoradiation in stage III unresectable non-small cell lung cancer Academic Article
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Immuno-gene therapy approaches for cancer: from in vitro studies to clinical trials Academic Article
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Immunological considerations for COVID-19 vaccine strategies Academic Article
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Immunosuppressive Effects of Allogeneic Blood Transfusions: Implications for the Patient with a Malignancy Academic Article
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Immunotherapy for recurrent miscarriage. Academic Article
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Immunotherapy in the Elderly Academic Article
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Immunotherapy with peptides. Academic Article
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Impact and Perceptions of Mandatory Tumor Biopsies for Correlative Studies in Clinical Trials of Novel Anticancer Agents Conference Paper
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Impact of 5-HT3 receptor antagonists on peripheral and central diseases Academic Article
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Impact of ENIGMA trials on nitrous oxide: a survey of Canadian anesthesiologists and residents Academic Article
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Impact of registration on clinical trials on infection risk in pediatric acute myeloid leukemia Academic Article
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Impact of the International Term Breech Trial on Clinical Practice and Concerns: A Survey of Centre Collaborators Academic Article
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Impactful Clinical Trials of 2012: What Clinicians Need to Know Academic Article
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Implantable Cardioverter Defibrillators in Cardiovascular Practice: Report of the Policy Conference of the North American Society of Pacing and Electrophysiology Academic Article
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Implementation of Timeline Reforms Speeds Initiation of National Cancer Institute-Sponsored Trials Academic Article
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Implication of Abnormal Human Trophoblast Karyotype for the Evidence-Based Approach to the Understanding, Investigation, and Treatment of Recurrent Spontaneous Abortion Academic Article
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Implications of TeqCES: efficacy and safety of gatifloxacin in community-acquired pneumonia Academic Article
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Improving Cancer Outcomes Through International Collaboration in Academic Cancer Treatment Trials Academic Article
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Improving academic leadership and oversight in large industry-sponsored clinical trials: the ARO-CRO model Academic Article
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Improving outcome reporting in clinical trial reports and protocols: study protocol for the Instrument for reporting Planned Endpoints in Clinical Trials (InsPECT) Academic Article
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In the Era of Systematic Reviews, Does the Size of an Individual Trial Still Matter? Academic Article
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In utero exposure to valproic acid and autism — A current review of clinical and animal studies Academic Article
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Incidence of childhood cancer in Canada during the COVID-19 pandemic Academic Article
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Incorporating Cultural Competence and Cultural Humility in Cardiovascular Clinical Trials to Increase Diversity Among Participants Academic Article
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Incorporating Utility-Based Quality-of-Life Assessment Measures in Clinical Trials Academic Article
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Increasing representation and diversity in cardiovascular clinical trial populations Academic Article
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Incretin treatment and risk of pancreatitis in patients with type 2 diabetes mellitus: systematic review and meta-analysis of randomised and non-randomised studies Academic Article
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Independent measurement of functional capacity in rheumatoid arthritis. Academic Article
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Indications, Technique, and Complications of Balloon Tamponade for Variceal Gastrointestinal Bleeding Academic Article
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Influence of censoring on conclusions of trials for women with metastatic breast cancer Academic Article
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Influence of eicosapentaenoic acid supplementation on lean body mass in cancer cachexia Academic Article
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Influenza Vaccination to Reduce Cardiovascular Morbidity and Mortality in Patients With COVID-19 Academic Article
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Inhaled Corticosteroids for Asthma: Common Clinical Quandaries Academic Article
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Inhibition of the bronchial response to respiratory heat exchange by increasing doses of terbutaline sulphate. Academic Article
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Initial and long-term treatment of deep venous thrombosis: recent clinical trials and their impact on patient management Academic Article
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Insights and Perspectives on Dietary Modifications to Reduce the Risk of Cardiovascular Disease Academic Article
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Insights into the role of thrombin in the pathogenesis of recurrent ischaemia after acute coronary syndrome Academic Article
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Insulin Therapy in People Who Have Dysglycemia and Type 2 Diabetes Mellitus: Can It Offer Both Cardiovascular Protection and Beta-Cell Preservation? Academic Article
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Integrating Mortality and Morbidity Outcomes Academic Article
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Intellectual property considerations in the development and use of HRQL measures for clinical trial research Academic Article
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Intensive Initial Oral Anticoagulation and Shorter Heparin Treatment in Deep Vein Thrombosis Academic Article
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Intensive glucose control and macrovascular outcomes in type 2 diabetes Academic Article
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Intention to treat analysis in clinical trials when there are missing data Academic Article
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Intention-to-treat principle. Academic Article
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Interaction of St John's wort with conventional drugs: systematic review of clinical trials Academic Article
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Interactions of Warfarin with Drugs and Food Academic Article
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Interleukin-6 receptor blockade in patients with COVID-19: placing clinical trials into context Academic Article
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Internal consistency reliability is a poor predictor of responsiveness Academic Article
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International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma Academic Article
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International Gynecologic Cancer Society (IGCS 2012) Academic Article
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Interpretation and power of a pooled index. Academic Article
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Interpretation of the evidence for the efficacy and safety of statin therapy Academic Article
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Interpretation of treatment changes in 6-minute walk distance in patients with COPD Academic Article
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Interventions for treatment of COVID-19: Second edition of a living systematic review with meta-analyses and trial sequential analyses (The LIVING Project) Academic Article
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Interventions for waterpipe tobacco smoking prevention and cessation: a systematic review Academic Article
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Interventions that potentially limit myocardial infarct size: Overview of clinical trials Academic Article
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Interventions to Improve Medication Reconciliation in Primary Care Academic Article
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Interventions to improve adherence to antiretroviral therapy: a systematic review and network meta-analysis Academic Article
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Intramuscular cimetidine and ranitidine as prophylaxis against gastric aspiration syndrome - a randomized double-blind study Academic Article
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Intramuscular versus oral gold therapy Academic Article
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Intranasal nedocromil sodium in the treatment of ragweed-allergic rhinitis. Academic Article
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Intrapericardial Amiodarone for the Prevention of Postoperative Atrial Fibrillation Academic Article
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Intravenous Streptokinase for Acute Myocardial Infarction Academic Article
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Intravenous and intracoronary fibrinolytic therapy in acute myocardial infarction: Overview of results on mortality, reinfarction and side-effects from 33 randomized controlled trials Academic Article
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Intravenous heparin for the prevention of stroke progression in acute partial stable stroke. Academic Article
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Intravenous magnesium in acute myocardial infarction. An effective, safe, simple, and inexpensive intervention. Academic Article
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Introduction Academic Article
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Investigating clinical heterogeneity in systematic reviews: a methodologic review of guidance in the literature Academic Article
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Investigator experiences with financial conflicts of interest in clinical trials Academic Article
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Investigator-initiated trials are more impartial Academic Article
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Investigator-led clinical research consortia: The Canadian Critical Care Trials Group Academic Article
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Irritable bowel syndrome and probiotics: from rationale to clinical use Academic Article
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Is Pain Ever “Normal”? Academic Article
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Is SABR Cost-Effective in Oligometastatic Cancer? An Economic Analysis of the SABR-COMET Randomized Trial Conference Paper
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Is antithrombotic prophylaxis required in cancer patients with central venous catheters? Still an open question Academic Article
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Is it Time for Sex-Specific Guidelines for Cardiovascular Disease? Academic Article
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Is it possible to reduce cardiovascular risk with glucose-lowering approaches? Academic Article
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Is it safe to use a proton pump inhibitor with clopidogrel? Academic Article
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Is postoperative radiotherapy for radically resected NSCLC detrimental and therefore unnecessary? Academic Article
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Is there a place for the crossover design in infertility trials? Academic Article
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Is there a role for antioxidant vitamins in the prevention of cardiovascular diseases? An update on epidemiological and clinical trials data. Academic Article
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Is there a role for the novel oral anticoagulants in patients with an acute coronary syndrome? A review of the clinical trials Academic Article
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Is there any evidence for immunologically mediated or immunologically modifiable early pregnancy failure? Academic Article
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Is weight loss an effective treatment for hypertension? The evidence against Academic Article
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Issues in quality-of-life measurement in clinical trials Academic Article
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Joint WFH‐ISTH session: issues in clinical trial design Academic Article
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Ketotifen and asthma. Academic Article
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Key design considerations for adaptive clinical trials: a primer for clinicians Academic Article
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Key stakeholder perceptions about consent to participate in acute illness research: a rapid, systematic review to inform epi/pandemic research preparedness Academic Article
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LDP-02 (Millenium). Academic Article
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Lack of evidence for a role of chemotherapy in the routine management of locally advanced head and neck cancer. Academic Article
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Landscape review of current HIV ‘kick and kill’ cure research - some kicking, not enough killing Academic Article
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Left Atrial Appendage Occlusion Academic Article
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Left Atrial Appendage Occlusion Does Not Eliminate the Need for Warfarin Academic Article
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Lessons from a systematic literature review of the effectiveness of recombinant factor VIIa in acquired haemophilia Academic Article
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Life-expectancy gains from pharmaceutical drugs: a critical appraisal of the literature Academic Article
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Limitation of myocardial infarction by early infusion of recombinant tissue-type plasminogen activator. Academic Article
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Long-Term Management of Venous Thromboembolism: Lessons from EINSTEIN CHOICE and Other Extension Trials Academic Article
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Long-Term Studies Assessing Outcomes of Ibrutinib Therapy in Patients With Del(11q) Chronic Lymphocytic Leukemia Academic Article
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Long-Term Tolerability of the Bisphosphonates in Postmenopausal Osteoporosis Academic Article
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Long-term Sequelae of Calf Vein Thrombosis Treated with Heparin or Low-dose Streptokinase Academic Article
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Long-term safety of biologics in dermatology Academic Article
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Loss to follow-up in orthopaedic clinical trials: a systematic review Academic Article
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Low Birth Weight and Home Intervention Strategies Academic Article
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Low Levels of High-Density Lipoprotein Cholesterol and Increased Risk of Cardiovascular Events in Stable Ischemic Heart Disease Patients Academic Article
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Low molecular weight heparin: a critical analysis of clinical trials. Academic Article
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Low molecular weight heparins in the treatment of unstable angina. Academic Article
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Low molecular weight heparins: deep vein thrombosis prophylaxis in elective hip surgery and thrombotic stroke. Academic Article
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Low-Molecular-Weight Heparin or Oral Anticoagulation for Secondary Prevention of Deep Vein Thrombosis in Cancer Patients Academic Article
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Low-molecular-weight heparin in the treatment of pulmonary embolism. Academic Article
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Low-molecular-weight heparin thromboprophylaxis in medical-surgical critically ill patients: A systematic review Academic Article
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Lumbar disc disease. Academic Article
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Lung Clearance Index as an Outcome Measure for Clinical Trials in Young Children with Cystic Fibrosis. A Pilot Study Using Inhaled Hypertonic Saline Academic Article
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Lung cancer practice guidelines: lessons learned and issues addressed by the Ontario Lung Cancer Disease Site Group. Academic Article
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MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation Academic Article
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Magnesium in acute myocardial infarction Academic Article
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Mammographic screening: case–control studies Academic Article
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Management Issues Unique to Regulatory Trials Academic Article
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Management Of Venous Thromboembolism: Optimization By Clinical Trials Academic Article
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Management consensus guidance for the use of rivaroxaban – an oral, direct factor Xa inhibitor Academic Article
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Management of Glucocorticoid-Induced Osteoporosis Academic Article
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Management of Platelet-Directed Pharmacotherapy in Patients With Atherosclerotic Coronary Artery Disease Undergoing Elective Endoscopic Gastrointestinal Procedures Academic Article
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Management strategies in unstable coronary artery disease-Current problems and future directions Academic Article
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Managing neuropsychiatric disease with transcranial magnetic stimulation. Academic Article
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Mandatory contrast-enhanced venography to detect deep-vein thrombosis (DVT) in studies of DVT prophylaxis: upsides and downsides Academic Article
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Maternal mental health and integrated programs for mothers with substance abuse issues. Academic Article
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Maximizing the benefits of thrombolytic therapy for acute myocardial infarction. Academic Article
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Measurement of health status Academic Article
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Measurement of health-related quality of life in heart failure Conference Paper
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Measurement of health-related quality of life in heart failure. Academic Article
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Measurements of Cardiac Output in Seriously Ill Patients Using a CO2 Rebreathing Method Academic Article
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Measuring Health-Related Quality of Life Academic Article
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Measuring disease-specific quality of life in clinical trials. Academic Article
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Measuring health status in chronic airflow limitation Academic Article
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Measuring health-related quality of life in rhinitis☆☆☆★ Academic Article
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Measuring patient‐reported outcomes: moving from clinical trials into clinical practice Academic Article
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Measuring quality of life in clinical trials: a taxonomy and review. Academic Article
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Medical Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy: A Consensus Statement of the American Diabetes Association and the European Association for the Study of Diabetes Academic Article
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Meeting report ESC Forum on Drug Eluting Stents, European Heart House, Nice, 27-28 September 2007 Academic Article
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Megestrol acetate plus minidose diethylstilbestrol in the treatment of carcinoma of the prostate. Academic Article
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Melatonin Antioxidative Defense: Therapeutical Implications for Aging and Neurodegenerative Processes Academic Article
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Melatonin agonists in primary insomnia and depression-associated insomnia: Are they superior to sedative-hypnotics? Academic Article
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Meta-analysis in medicine Where we are and where we want to go Academic Article
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Meta-analysis: A practical decision making tool for surgeons Academic Article
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Metabolomic adaptations and correlates of survival to immune checkpoint blockade Academic Article
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Method guidelines for Cochrane Musculoskeletal Group systematic reviews. Academic Article
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Methodologic challenges in the development of utility measures of health-related quality of life in rheumatoid arthritis Academic Article
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Methodologic discussions for using and interpreting composite endpoints are limited, but still identify major concerns Academic Article
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Methodologic issues in trials of antiemetics. Academic Article
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Methodologic pitfalls in assessing the efficacy of recombinant follicle-stimulating hormone versus human menopausal gonadotropin in assisted reproduction Academic Article
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Methodologic problems in clinical trials in heart failure Academic Article
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Methodological Issues in Systematic Reviews and Meta-Analyses of Observational Studies in Orthopaedic Research Academic Article
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Methodological and statistical issues of quality of life (QoL) and economic evaluation in cancer clinical trials: report of a workshop Academic Article
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Methodological issues in infertility research Academic Article
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Methods to convert continuous outcomes into odds ratios of treatment response and numbers needed to treat: meta-epidemiological study Academic Article
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Methotrexate/fluorouracil scheduling influences normal tissue toxicity but not antitumor effects in patients with squamous cell head and neck cancer: results from a randomized trial. Academic Article
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Metoprolol in acute myocardial infarction (MIAMI). A randomised placebo-controlled international trial Academic Article
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Miglustat as a therapeutic agent: prospects and caveats Academic Article
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Minimal Risk Remains an Open Question Academic Article
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Missing data and the trouble with LOCF Academic Article
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Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis Academic Article
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Monitoring strontium ranelate therapy in patients with osteoporosis Academic Article
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Montelukast for the treatment of asthma in the adult population Academic Article
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More than just hype. Academic Article
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Mortality rates and risk factors for asymptomatic deep vein thrombosis in medical patients Academic Article
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Motivational factors for medical oncologists' participation in cancer treatment protocols. Academic Article
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Motor Unit Counting and the Caffeine Contracture Test in Malignant Hyperthermia Academic Article
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Moving forward in clinical research with master protocols Academic Article
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Moving promising research findings to the clinic: Methodological issues in the design and conduct of clinical trials of retinoids Academic Article
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Multicenter Collaboration in Observational Research: Improving Generalizability and Efficiency Academic Article
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Multiple uses of forest plots in presenting analysis results in health research: A Tutorial Academic Article
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National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: VI. Design of Clinical Trials Working Group Report Academic Article
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National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: VI. The 2014 Clinical Trial Design Working Group Report Academic Article
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Natural Health Product-Drug Interactions Academic Article
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Natural health product–HIV drug interactions: a systematic review Academic Article
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Need for Quality Improvement in Renal Systematic Reviews Academic Article
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Need for a new paediatric post thrombotic sequelae outcome measure for non-extremity thrombosis Academic Article
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Net clinical benefit of dabigatran vs. warfarin in venous thromboembolism: analyses from RE-COVER®, RE-COVER™ II, and RE-MEDY™ Academic Article
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New Anticoagulant Therapy Academic Article
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New Anticoagulants Academic Article
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New Anticoagulants for Treatment of Venous Thromboembolism Academic Article
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New Antithrombotics Academic Article
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New anticoagulants Conference Paper
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New anticoagulants in atrial fibrillation management Conference Paper
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New anticoagulants. Academic Article
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New anticoagulants: an update. Academic Article
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New antithrombotic agents Academic Article
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New horizons on the landscape of AYA oncology Academic Article
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New oral anticoagulants for stroke prevention in atrial fibrillation: impact of study design, double counting and unexpected findings on interpretation of study results and conclusions Academic Article
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New oral anticoagulants: which one should my patient use? Academic Article
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New policies to address the global burden of childhood cancers Academic Article
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New strategies for clinical trials in patients with sepsis and septic shock Academic Article
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New therapeutic strategies to treat human cancers expressing mutant p53 proteins Academic Article
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Newer Antiepileptic Drugs in Bipolar Disorder Academic Article
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Newly Diagnosed Malignancy in Patients with VenousThromboembolism. Search or Wait and See? Academic Article
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No surgical innovation without evaluation: the IDEAL recommendations Academic Article
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Nocturnal Gastric Acid Secretion: Its Importance in the Pathophysiology and Rational Therapy of Duodenal Ulcer Academic Article
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Non-vitamin K antagonist oral anticoagulants (NOACs): No longer new or novel Academic Article
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Non-vitamin-K oral anticoagulants (NOACs) for the prevention of secondary stroke Academic Article
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Noninferiority Margin Size and Acceptance of Trial Results: Contingent Valuation Survey of Clinician Preferences for Noninferior Mortality Academic Article
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Noninvasive Cardiac Monitoring for Detecting Paroxysmal Atrial Fibrillation or Flutter After Acute Ischemic Stroke Academic Article
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Nonrheumatic atrial fibrillation. Risk of stroke and role of antithrombotic therapy. Academic Article
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Norfloxacin: a new quinolone. Committee on Antimicrobial Agents, Canadian Infectious Disease Society. Academic Article
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Novel Oral Factor Xa and Thrombin Inhibitors in the Management of Thromboembolism Academic Article
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Novel antithrombotic strategies for treatment of venous thromboembolism Academic Article
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Novel antithrombotic therapies for the prevention of stroke in patients with atrial fibrillation. Academic Article
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Novel approaches and perspectives in allergen immunotherapy Academic Article
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Novel paediatric anticoagulants: a review of the current literature Academic Article
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Novel platelet products, substitutes and alternatives Academic Article
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Novel targeted therapies for eosinophilic disorders Academic Article
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OCTANE (Ontario-Wide Cancer Targeted Nucleic Acid Evaluation): A Platform for Intraprovincial, National, and International Clinical Data-Sharing Academic Article
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Obesity and renal cell carcinoma: epidemiology, underlying mechanisms and management considerations Academic Article
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Obtaining medically meaningful answers from an overview of randomized clinical trials Academic Article
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Off the beaten path: conducting ethical pragmatic trials with marginalized populations. Academic Article
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Omalizumab and the immune system: an overview of preclinical and clinical data Academic Article
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Once-Daily Therapy with Ceftriaxone Compared with Daily Multiple-Dose Therapy with Cefotaxime for Serious Bacterial Infections: A Randomized, Double-Blind Study Academic Article
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Oncolytic Viruses: Therapeutics With an Identity Crisis Academic Article
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Ontario Cancer Research Ethics Board: Lessons Learned From Developing a Multicenter Regional Institutional Review Board Academic Article
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Optimal reversal of vitamin K antagonists Academic Article
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Optimal sampling in derivation studies was associated with improved discrimination in external validation for heart failure prognostic models Academic Article
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Optimizing Prophylaxis of Venous Thromboembolism Academic Article
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Optimizing the Use of Abciximab and Intracoronary Stents in Patients with Acute ST Elevation Myocardial Infarction Academic Article
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Oral Anticoagulants Academic Article
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Oral Vitamin E Supplementation for the Prevention of Anemia in Premature Infants: A Controlled Trial Academic Article
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Oral anticoagulants in coronary heart disease (Section IV) Position paper of the ESC Working Group on Thrombosis – Task Force on Anticoagulants in Heart Disease Academic Article
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Oral anticoagulants in patients with coronary artery disease: an inexpensive and effective strategy Academic Article
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Oral anticoagulants. Mechanism of action, clinical effectiveness, and optimal therapeutic range. Academic Article
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Oral antiplatelet therapy. Academic Article
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Organ at Risk Dose Constraints in SABR: A Systematic Review of Active Clinical Trials Academic Article
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Osteoarthritis antirheumatic drug trials. I. Effects of standardization procedures on observer dependent outcome measures. Academic Article
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Osteoarthritis antirheumatic drug trials. II. Tables for calculating sample size for clinical trials. Academic Article
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Osteoarthritis antirheumatic drug trials. III. Setting the delta for clinical trials--results of a consensus development (Delphi) exercise. Academic Article
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Osteoarthritis: symptoms, signs and source of pain Academic Article
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Osteoporosis clinical trials endpoints: candidate variables and clinimetric properties. Academic Article
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Outcome Measures in Rheumatology - Interventions for medication Adherence (OMERACT-Adherence) Core Domain Set for Trials of Interventions for Medication Adherence in Rheumatology: 5 Phase Study Protocol Academic Article
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Outcome measures for clinical research in sepsis: A report of the 2nd Cambridge Colloquium of the International Sepsis Forum Academic Article
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Outcomes Assessment in Fracture Healing Trials: A Primer Academic Article
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Outcomes of Passable and Non-passable Strictures in Clinical Trials of Crohn’s Disease: A Post-hoc Analysis Academic Article
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Ovarian ablation as adjuvant therapy for early-stage breast cancer Academic Article
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Overview of randomised trials of diuretics in pregnancy. Academic Article
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PET imaging for pediatric oncology: An assessment of the evidence Academic Article
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Pain during angiography: a randomized double-blind trial comparing ioxaglate and diatrizoate. Academic Article
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Panic prescribing has become omnipresent during the COVID-19 pandemic Academic Article
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Participation in HIV vaccine trials: listening to participant & community concerns. Academic Article
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Participation of community medical oncologists in clinical research trials. Academic Article
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Pathophysiologic and therapeutic importance of tissue ACE: a consensus report. Academic Article
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Patient Engagement and Shared Decision-Making Academic Article
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Patient Use of Smartphones to Communicate Subjective Data in Clinical Trials Academic Article
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Patient compliance and the conduct and interpretation of therapeutic trials Academic Article
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Patient enrollment and logistical problems top the list of difficulties in clinical research: a cross-sectional survey Academic Article
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Patient-important activity and participation outcomes in clinical trials involving children with chronic conditions Academic Article
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Patient-level compared with study-level meta-analyses demonstrate consistency of D-dimer as predictor of venous thromboembolic recurrences Academic Article
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Patients’ preferences for enrolment into critical-care trials Academic Article
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Pediatric Stroke Initiatives and Preliminary Studies: What Is Known and What Is Needed? Conference Paper
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Pediatric oncology clinical trial participation where the geography is vast: Development of a clinical research system for tertiary and satellite centers in Ontario, Canada Academic Article
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Pemetrexed safety and dosing strategy Academic Article
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Peptide immunotherapy for allergic disease Academic Article
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Peptide immunotherapy for allergic diseases Academic Article
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Peptide-Mediated Immune Responses in Specific Immunotherapy Academic Article
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Peptide-based Vaccines in the Treatment of Specific Allergy Academic Article
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Peptide-based vaccination: where do we stand? Academic Article
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Periodic health examination, 1991 update: 6. Acetylsalicylic acid and the primary prevention of cardiovascular disease. Canadian Task Force on the Periodic Health Examination. Academic Article
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Perioperative Management of Patients Receiving Oral Anticoagulants Academic Article
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Perioperative Management of Patients Receiving Oral Anticoagulants Academic Article
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Perioperative anticoagulant management in patients with atrial fibrillation: practical implications of recent clinical trials Academic Article
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Pharmacological Actions of Sulodexide Academic Article
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Pharmacological Treatment of Ankylosing Spondylitis Academic Article
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Pharmacological Treatment of Hypertension in Pregnancy Academic Article
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Phase 1 Trial Design: Is 3 + 3 the Best? Academic Article
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Phase II study of Triapine® in patients with metastatic renal cell carcinoma: a trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC IND.161) Academic Article
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Phase II trial evaluating continuous infusion of etoposide, cisplatin, and hexamethylmelamine in extensive-disease small cell carcinoma of the lung. Academic Article
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Pitfalls in the design and analysis of efficacy trials in subfertility: Associate editor's commentary: on the article 'Common statistical errors in the design and analysis of subfertility trials' by A.Vail and E.Gardner. Academic Article
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Placebo use and unblinding in COVID-19 vaccine trials: recommendations of a WHO Expert Working Group Academic Article
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Platelet Utilization: A Canadian Blood Services Research and Development Symposium Academic Article
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Platelet count or bleeding as the outcome in ITP trials? Academic Article
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Platelet inhibitors in the treatment of thrombosis. Academic Article
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Platelet-Inhibiting Drugs in the Prevention of Clinical Thrombotic Disease Academic Article
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Platelet-Inhibiting Drugs in the Prevention of Clinical Thrombotic Disease Academic Article
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Platelet-Inhibiting Drugs in the Prevention of Clinical Thrombotic Disease Academic Article
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Point/counterpoint: early-stage Hodgkin lymphoma and the role of radiation therapy. Academic Article
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Polypill Variants (Quarter Pill Trials) Academic Article
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Pooled outcome measures in arthritis: the pros and cons. Academic Article
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Poor Cognitive Function and Risk of Severe Hypoglycemia in Type 2 Diabetes Academic Article
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Post-thrombotic syndrome in children: a systematic review of frequency of occurrence, validity of outcome measures, and prognostic factors Academic Article
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Potential for altering the natural history of congestive heart failure: Need for large clinical trials Academic Article
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Potential of new anticoagulants in patients with cancer Academic Article
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Power function arguments in support of an alternative approach for analyzing management trials Academic Article
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Practical Application of125I-Fibrinogen Leg Scanning Academic Article
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Practical Model-Based Dose Finding in Early-Phase Clinical Trials Academic Article
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Practices and Attitudes of Swiss Stakeholders Regarding Investigator-Initiated Clinical Trial Funding Acquisition and Cost Management Academic Article
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Preclinical and Clinical Evidence of Antioxidant Effects of Antidepressant Agents: Implications for the Pathophysiology of Major Depressive Disorder Academic Article
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Predictors of dropout from cardiac exercise rehabilitation Academic Article
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Pregnancy and COVID‐19: pharmacologic considerations Academic Article
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Pregnant and lactating women should be included in clinical trials for cardiovascular disease Academic Article
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Preoperative or Postoperative Therapy for Stage II or III Rectal Cancer: An Updated Practice Guideline Academic Article
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Presentation approaches for enhancing interpretability of patient-reported outcomes (PROs) in meta-analysis: a protocol for a systematic survey of Cochrane reviews Academic Article
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Prevalence of endoscopic improvement and remission according to patient‐reported outcomes in ulcerative colitis Academic Article
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Preventing Cardioembolic Stroke in Atrial Fibrillation with Dabigatran Academic Article
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Preventing Venous Thromboembolism in Critically Ill Patients Academic Article
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Prevention and Treatment of Hormone-Associated Venous Thromboembolism: A Patient Management Approach Academic Article
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Prevention of Thrombotic Disorders in Cancer Patients Undergoing Chemotherapy Academic Article
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Prevention of Venous Thromboembolism Academic Article
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Prevention of Venous Thrombosis After Elective Hip Surgery Academic Article
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Prevention of coronary heart disease with aspirin and clopidogrel: efficacy, safety, costs and cost-effectiveness Academic Article
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Prevention of deep vein thrombosis in potential neurosurgical patients. A randomized trial comparing graduated compression stockings alone or graduated compression stockings plus intermittent pneumatic compression with control Academic Article
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Prevention of venous thromboembolism in medically ill patients: a clinical update Academic Article
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Primary Prevention of Child Physical Abuse and Neglect: A Critical Review. Part I Academic Article
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Primary Prevention of Child Sexual Abuse: A Critical Review. Part II Academic Article
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Primary angioplasty for ST-segment elevation myocardial infarction: ready for prime time? Academic Article
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Pro: “Anti-platelet therapy is an alternative to oral anticoagulation for atrial fibrillation” Academic Article
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Probabilistic Analysis of Cost-Effectiveness Models: Choosing between Treatment Strategies for Gastroesophageal Reflux Disease Academic Article
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Probabilistic Analysis of Cost-Effectiveness Models: Choosing between Treatment Strategies for Gastroesophageal Reflux Disease Academic Article
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Proceedings of a workshop Academic Article
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Proceedings of the Fifth International Conference on Recent Advances and Future Directions in Endocrine Therapy for Breast Cancer: Conference Summary Statement Conference Paper
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Proceedings: Failure of aspirin and dipyridamole to influence the incidence of leg scan detected venous thrombosis after elective hip surgery. Academic Article
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Process evaluation in the field: global learnings from seven implementation research hypertension projects in low-and middle-income countries Academic Article
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Progesterone Receptor Loss Correlates with Human Epidermal Growth Factor Receptor 2 Overexpression in Estrogen Receptor–Positive Breast Cancer Conference Paper
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Prognostic value of blood pressure measured during hospitalization after acute myocardial infarction: an insight from survival trials Academic Article
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Progress review: the relationship between dose of aspirin, side-effects and antithrombotic effectiveness. Academic Article
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Prophylaxis of upper gastrointestinal bleeding in intensive care units Academic Article
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Proposal for Standardized Definitions for Efficacy End Points in Adjuvant Breast Cancer Trials: The STEEP System Academic Article
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Pros and Cons of Composite Endpoints in Anesthesia Trials Academic Article
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Prospective randomized trial of one-hour sequential versus simultaneous methotrexate plus 5-fluorouracil in advanced and recurrent squamous cell head and neck cancer. Academic Article
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Prospects of the Clinical Utilization of Melatonin Academic Article
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Prostate cancer radiotherapy 2002: the way forward. Academic Article
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Protecting Human Research Participants: Reading vs Understanding the Consent Form Academic Article
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Protocol Understanding and Anxiety in Perioperative Clinical Trial Patients Approached for Consent on the Day of Surgery Academic Article
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Protocol-based treatment for children with cancer in low income countries in Latin America: A report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)-Part II Academic Article
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Proton pump inhibitors in acute non-variceal upper gastrointestinal bleeding Academic Article
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Psoriasis of the nail: Anatomy, pathology, clinical presentation, and a review of the literature on therapy Academic Article
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Q&A: Antibiotic resistance: what more do we know and what more can we do? Academic Article
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Quality of life in stage II breast cancer: an instrument for clinical trials. Academic Article
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Quality of life in the Canadian Implantable Defibrillator Study (CIDS) Academic Article
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Quality of life questionnaires: Does statistically significant = clinically important? Academic Article
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Qualiveen: A Urinary Disorder−Specific Instrument for Use in Clinical Trials in Multiple Sclerosis Academic Article
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RANDOMISED CLINICAL TRIAL OF STRATEGIES FOR IMPROVING MEDICATION COMPLIANCE IN PRIMARY HYPERTENSION Academic Article
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RANDOMISED COMPARISON OF TWO INTENSITIES OF ORAL ANTICOAGULANT THERAPY AFTER TISSUE HEART VALVE REPLACEMENT Academic Article
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ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions Academic Article
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Radiation Therapy Oncology Group. Research Plan 2002-2006. Gynecology Cancer Working Group. Academic Article
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Radiation in early-stage Hodgkin lymphoma. Academic Article
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Radiological changes in rheumatoid arthritis: measurement of area of juxta-articular bone as outcome event in clinical therapeutic trials of antirheumatic drugs. Academic Article
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Randomisation to protect against selection bias in healthcare trials Academic Article
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Randomised comparison of early versus late induction of labour in post-term pregnancy Academic Article
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Randomized Control Trials and the EC-IC Arterial Anastomosis Procedure Academic Article
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Randomized clinical trial of an oscillating air mattress in preterm infants: Effect on apnea, growth, and development Academic Article
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Randomized clinical trial of supportive follow-up for cigarette smokers in a family practice. Academic Article
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Randomized trial of high-dose cytarabine versus amsacrine in acute myelogenous leukemia in relapse: a Leukemia Intergroup Study. Academic Article
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Randomized trials in orthopaedics Academic Article
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Real-Life Research Academic Article
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Reasons for the loss of sensitivity and specificity of methodologic MeSH terms and textwords in MEDLINE. Academic Article
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Reassessing Quality-of-Life Instruments in the Evaluation of New Drugs Academic Article
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Reassessing the Th2 cytokine basis of asthma Academic Article
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Recent clinical trials in the treatment of venous thromboembolism and unstable angina with low molecular weight heparins Academic Article
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Recommendations for Clinical Trials in ICH Academic Article
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Recommendations for national and local regulatory authorities concerning research in genetic markers of disease Academic Article
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Recommendations for standardized risk factor definitions in pediatric hospital‐acquired venous thromboembolism to inform future prevention trials: communication from the SSC of the ISTH Academic Article
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Recommendations for the implementation of platelet autoantibody testing in clinical trials of immune thrombocytopenia Academic Article
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Recommended Patient-Reported Core Set of Symptoms to Measure in Prostate Cancer Treatment Trials Academic Article
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Recovery room oxygenation: A comparison of nasal catheters and 40 per cent oxygen masks Academic Article
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Recruitment for an efficacy study in chemoprevention—The concerned smoker study Academic Article
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Recurrent events in meta-analysis of multiple clinical trials. Academic Article
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Recurrent spontaneous early pregnancy loss and low dose aspirin. Academic Article
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Reduced joint counts in rheumatoid arthritis clinical trials Academic Article
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Reducing the risk of urgent revascularization for unstable angina: A randomized clinical trial Academic Article
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Reduction in Fatal Pulmonary Embolism and Venous Thrombosis by Perioperative Administration of Subcutaneous Heparin Academic Article
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Reduction of ventricular arrhythmias by early intravenous atenolol in suspected acute myocardial infarction. Academic Article
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Regularly inhaled β-agonists in stable asthma Academic Article
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Regulatory decisions pertaining to aprotinin may be putting patients at risk Academic Article
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Relation of exercise to the recurrence rate of myocardial infarction in men Academic Article
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Relationship Between A1C and Fasting Plasma Glucose in Dysglycemia or Type 2 Diabetes Academic Article
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Relevant clinical end points in biphosphonate trials. Academic Article
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Reliability of Trial Information Across Registries for Trials With Multiple Registrations Academic Article
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Replication of machine learning methods to predict treatment outcome with antidepressant medications in patients with major depressive disorder from STAR*D and CAN-BIND-1 Academic Article
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Report of the Conference on Low Blood Cholesterol: Mortality Associations. Academic Article
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Reporting Guidelines for Imaging Research Academic Article
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Reporting of IMMPACT-recommended core outcome domains among trials assessing opioids for chronic non-cancer pain Academic Article
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Reproducibility of impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) classification: a systematic review Academic Article
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Researching the Cost of Research Academic Article
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Resolving Controversies in Hip Fracture Care: The Need for Large Collaborative Trials in Hip Fractures Academic Article
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Respiratory Muscle Training in Chronic Airflow Limitation: A Meta-Analysis Academic Article
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Response of borderline and schizotypal patients to small doses of thiothixene and haloperidol Academic Article
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Resumption of anticoagulant therapy after anticoagulant-related gastrointestinal bleeding Academic Article
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Rhinitis management: the patient’s perspective Academic Article
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Rigorous Evaluation Academic Article
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Riociguat for the treatment of pulmonary hypertension Academic Article
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Risk factors for nausea and vomiting after general anaesthesia. Academic Article
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Risk of heparin-induced thrombocytopenia in patients receiving thromboprophylaxis Academic Article
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Risk-Benefit Assessment of Antiarrhythmic Drugs Academic Article
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Rituximab in lymphoma: A systematic review and consensus practice guideline from Cancer Care Ontario Academic Article
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Role of antithrombotic therapy in atrial fibrillation. Academic Article
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Role of the renin-angiotensin-aldosterone system in atrial fibrillation and cardiac remodeling. Academic Article
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SINGLE-PATIENT RANDOMISED CLINICAL TRIAL Use in Determining Optimum Treatment for Patient with Inflammation of Kock Continent Ileostomy Reservoir Academic Article
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SMART therapy Academic Article
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SUBJECTIVE ASSESSMENT OF THE EFFECT OF CATARACT-SURGERY AND A REVIEW OF LONG-TERM AIMS Academic Article
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Safety and efficacy of gatifloxacin in community-acquired pneumonia: rationale for the Tequin Clinical Experience Study (TeqCES) Conference Paper
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Sample Size and Power in Psychiatric Research* Academic Article
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Sample Size in the Planning and Interpretation of Clinical Trials Academic Article
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Sample size and power considerations in network meta-analysis Academic Article
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Sample size and power issues in estimating incremental cost-effectiveness ratios from clinical trials data Academic Article
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Sample size for randomized trials in stroke prevention. How many patients do we need? Academic Article
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Scientific Requirements for Diagnostic Tests in Gastroenterology Academic Article
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Sclerostin: More than a bone formation brake Academic Article
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Scoping review and characteristics of publicly available checklists for assessing clinical trial feasibility Academic Article
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Screening of ARDS patients using standardized ventilator settings: influence on enrollment in a clinical trial Academic Article
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Searching MEDLINE for Randomized Clinical Trials Involving Care of the Newborn Academic Article
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Second-line chemotherapy of stage III-IV ovarian carcinoma: a randomized comparison of melphalan to melphalan and hexamethylmelamine in patients with persistent disease after doxorubicin and cisplatin. Academic Article
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Selected Principles of the Measurement and Setting of Priorities of Death, Disability, and Suffering in Clinical Trials Academic Article
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Selection and combination of outcome measures. Academic Article
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Selection and results of antiplatelet therapy in the prevention of stroke and myocardial infarction Academic Article
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Selective factor Xa inhibition for thromboprophylaxis Academic Article
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Selenium and Lung Cancer: A Systematic Review and Meta Analysis Academic Article
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Self-recording of blood pressure in the management of hypertension. Academic Article
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Sensitive Clinical Queries retrieved relevant systematic reviews as well as primary studies: an analytic survey Academic Article
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Sentinel Lymph Node Biopsy in Breast Cancer: Canadian Practice Patterns Conference Paper
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Serious adverse events in academic critical care research Academic Article
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Serotonin Agents in the Treatment of Acquired Brain Injury Academic Article
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Setting a standard for venous thromboembolism prophylaxis Academic Article
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Sex and Gender Subgroup Analyses of Randomized Trials Academic Article
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Sharing interim trial results by the Data Safety Monitoring Board with those responsible for the trial’s conduct and progress: a narrative review Academic Article
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Should Clinical Trials Be Terminated Early? Academic Article
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Should Patients With Ischemic Stroke or Transient Ischemic Attack With Atrial Fibrillation and Microbleeds Be Anticoagulated? Academic Article
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Should patients with stable coronary artery disease be treated with ACE inhibitor therapy? Academic Article
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Should recommendations about starting inhaled corticosteroid treatment for mild asthma be based on symptom frequency: a post-hoc efficacy analysis of the START study Academic Article
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Simulation Modeling of Cancer Clinical Trials: Application to Omitting Radiotherapy in Low-risk Breast Cancer Academic Article
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Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies Academic Article
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Sir William Osler (1849-1919): His Opinion of Modern Therapeutics Academic Article
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Small Subcutaneous Doses of Heparin in Prevention of Venous Thrombosis Academic Article
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Smoking cessation in primary care. A randomized controlled trial of nicotine-bearing chewing gum. Academic Article
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Society of Interventional Radiology Research Reporting Standards for Prostatic Artery Embolization Academic Article
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Sodium cromoglycate in ragweed-allergic conjunctivitis Academic Article
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Some features of miocamycin in the gynecological field: pharmacokinetic data using preoperative administration and therapeutic aspects against chlamydial infections. Academic Article
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Sources of bias in diagnostic accuracy studies and the diagnostic process Academic Article
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Standard 5: Selection, Measurement, and Reporting of Outcomes in Clinical Trials in Children Academic Article
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Standard Operating Procedures: The Devil Is in the Details Academic Article
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Standardized Bleeding Definitions for Cardiovascular Clinical Trials Academic Article
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Standardized audiotape versus recorded consultation to enhance informed consent to a clinical trial in breast oncology Academic Article
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Starting prophylaxis for venous thromboembolism postoperatively Academic Article
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Statistical Significance in Trauma Research: Too Unstable to Trust? Academic Article
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Statistical issues in the use of dynamic allocation methods for balancing baseline covariates Academic Article
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Statistical methods for unidirectional switch designs: Past, present, and future Academic Article
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Statistics Commentary Series Academic Article
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Stopping Trials for Benefit Can (Sometimes) Benefit Patients Academic Article
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Strategies for patient recruitment into clinical trials Academic Article
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Strategies to enhance patient recruitment and retention in research involving patients with a first episode of mental illness Academic Article
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Stratification according to HGG-IMMUNO RPA model predicts outcome in a large group of patients with relapsed malignant glioma treated by adjuvant postoperative dendritic cell vaccination Academic Article
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Stress Ulcer Prophylaxis: Gastrointestinal Bleeding and Nosocomial Pneumonia Best Evidence Synthesis Academic Article
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Stroke and Cardiovascular Diseases: The Need for a Global Approach for Prevention and Drug Development Academic Article
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Student-designed clinical trials: evaluating self-directed learning in pharmacology Academic Article
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Studies on the frequency of heparin-associated thrombocytopenia Academic Article
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Studies on the medical treatment of deep vein thrombosis. Academic Article
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Study design attributes influenced patients' willingness to participate in clinical research: a randomized vignette-based study Academic Article
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Subjective assessment of the effect of cataract surgery and a review of long term aims Academic Article
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Sub‐lingual Immunotherapy: World Allergy Organization Position Paper 2009 Academic Article
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Successors to heparin: new antithrombotic agents. Academic Article
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Sucralfate: The Bangkok review Academic Article
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Summaries of findings, descriptions of interventions, and information about adverse effects would make reviews more informative Academic Article
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Superiority of Alternating Non-Cross-Resistant Chemotherapy in Extensive Small Cell Lung Cancer Academic Article
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Surrogate Markers in Clinical Studies: Problems Solved or Created? Academic Article
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Survey of professional views on sharing interim results by the Data Safety Monitoring Board (DSMB): what to share, with whom and why Academic Article
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Survival results from a phase III study of simultaneous versus 1-hour sequential methotrexate—5-fluorouracil chemotherapy in head and neck cancer Academic Article
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Symptom-Based Outcome Measures for Dyspepsia and GERD Trials: A Systematic Review Academic Article
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Systematic Literature Review and Meta-Analysis Academic Article
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Systematic Overview of Warfarin and Its Drug and Food Interactions Academic Article
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Systematic Reviews of Nonrandomized Clinical Studies in the Orthopaedic Literature Academic Article
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Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine initiative: clinical indicators Academic Article
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Systematic review and consensus definitions for the Standardized Endpoints in Perioperative Medicine (StEP) initiative: cardiovascular outcomes Academic Article
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Systematic review and meta-analysis methodology Academic Article
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Systematic review of basket trials, umbrella trials, and platform trials: a landscape analysis of master protocols Academic Article
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Systematic review: conservative treatments for secondary lymphedema Academic Article
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Systematic review: persistence and severity in gastroesophageal reflux disease Academic Article
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Systematic reviewers commonly contact study authors but do so with limited rigor Academic Article
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Systematic scoping review identifies heterogeneity in outcomes measured in adolescent depression clinical trials Academic Article
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Systemic Adjuvant Therapy for Node-Negative Breast Cancer: Proven or Premature? Academic Article
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Systemic adjuvant therapy for node-negative breast cancer. Academic Article
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Systemic therapy for previously untreated advanced BRAF-mutated melanoma: navigating a shifting landscape Academic Article
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Tamoxifen May Be an Effective Adjuvant Treatment for BRCA1-Related Breast Cancer Irrespective of Estrogen Receptor Status Academic Article
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Tamoxifen added to adjuvant chemotherapy in premenopausal women with early breast cancer: is it standard practice or still a subject for study? Academic Article
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Targeting Genes for Treatment in Idiopathic Pulmonary Fibrosis: Challenges and Opportunities, Promises and Pitfalls Academic Article
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Targeting the epidermal growth factor receptor in non-small-cell lung cancer: Who, which, when, and how? Academic Article
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Technical review: High-intensity focused ultrasound for prostate cancer. Academic Article
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Temporal Trends and Clinical Trial Characteristics Associated With the Inclusion of Women in Heart Failure Trial Steering Committees: A Systematic Review Academic Article
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Testing for heterogeneity among the components of a binary composite outcome in a clinical trial Academic Article
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The American College of Rheumatology preliminary core set of disease activity measures for rheumatoid arthritis clinical trials. The Committee on Outcome Measures in Rheumatoid Arthritis Clinical Trials. Academic Article
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The CONSORT Patient-Reported Outcome (PRO) extension: implications for clinical trials and practice Academic Article
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The Canadian American Ticlopidine Study (CATS) in thromboembolic stroke. Design, organization, and baseline results. Academic Article
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The Case of the Missing Data: Methods of Dealing with Dropouts and other Research Vagaries Academic Article
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The Clinical Utility of Kidney Injury Molecule 1 in the Prediction, Diagnosis and Prognosis of Acute Kidney Injury: A Systematic Review Academic Article
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The Guideline-Policy Gap in Direct-Acting Oral Anticoagulants Usage in Atrial Fibrillation: Evidence, Practice, and Public Policy Considerations Academic Article
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The Ineffectiveness of Immunosuppressive Therapy in Lymphocytic Myocarditis: An Overview Academic Article
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The Management of Hypertension in the Overweight and Obese Patient Academic Article
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The McMaster Health Index Questionnaire as a measure of quality of life for patients with rheumatoid disease. Academic Article
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The new oral anticoagulants Academic Article
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The protective effect of inhaled chlorpheniramine and atropine on bronchoconstriction stimulated by airway cooling. Academic Article
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The ratio of means method as an alternative to mean differences for analyzing continuous outcome variables in meta-analysis: A simulation study Academic Article
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The role of tamoxifen and aromatase inhibitors/inactivators in postmenopausal patients Conference Paper
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The role of tamoxifen and aromatase inhibitors/inactivators in postmenopausal patients. Academic Article
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The sirens are singing: The perils of trusting trials stopped early and subgroup analyses* Academic Article
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The use and abuse of surrogate endpoints in clinical research in transfusion medicine Academic Article
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Thrombolysis for restoration of patency to haemodialysis central venous catheters: a systematic review. Academic Article
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Unstable Angina and Non–ST-Elevation Myocardial Infarction Academic Article
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Update and Next Steps for Real-World Translation of Interventions for Type 2 Diabetes Prevention: Reflections From a Diabetes Care Editors’ Expert Forum Academic Article
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Updates in thrombosis in pediatrics: where are we after 20 years? Academic Article
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Urgent Clinical Challenges in Children With Ischemic Stroke Academic Article
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Urgently seeking efficiency and sustainability of clinical trials in global health Academic Article
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Use and Misuse of Surrogate Outcomes in Arrhythmia Trials Academic Article
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Use of Antithrombotic Agents During Pregnancy Conference Paper
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Use of GRADE in evidence syntheses published in high-impact-factor nutrition journals: A methodological survey Academic Article
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Use of a Qualification Phantom for PET Brain Imaging in a Multicenter Consortium: A Collaboration Between the Pediatric Brain Tumor Consortium and the SNMMI Clinical Trials Network Academic Article
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Use of epoetin in patients with cancer: evidence-based clinical practice guidelines of the American Society of Clinical Oncology and the American Society of Hematology Academic Article
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Use of stable isotopes to determine compliance Academic Article
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Usefulness of propafenone for recurrent paroxysmal atrial fibrillation Academic Article
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User's Guide to a Meta-Analysis about an Orthopaedic Implant Academic Article
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Users' Guides to the Medical Literature Academic Article
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Users' Guides to the Medical Literature Academic Article
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Users' guide to detecting misleading claims in research: Misleading claims may be symptom of even more serious flaws Academic Article
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Users' guides to the medical literature. II. How to use an article about therapy or prevention. A. Are the results of the study valid? Evidence-Based Medicine Working Group Academic Article
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Using Humanistic Health Outcomes Data in Asthma Academic Article
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Using Value-of-Information Methods when the Disease Is Rare and the Treatment Is Expensive—The Example of Hemophilia A Academic Article
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Using baseline measurements in the two-period crossover clinical trial Academic Article
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Using the Maximum Test Statistic in the Two-Period Crossover Clinical Trial Academic Article
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Vagal Afferent Stimulation as a Cardioprotective Strategy? Introducing the Concept Academic Article
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Validation of pH Dataloggers for Pharmacologic Studies Academic Article
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Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. Academic Article
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Value of Information and Pricing New Healthcare Interventions Academic Article
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Variation in outcome reporting in studies on obesity in pregnancy—A systematic review Academic Article
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Vasopressin in pediatric shock and cardiac arrest Academic Article
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Venous and arterial thrombosis – pathogenesis and the rationale for anticoagulation Academic Article
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Venous thromboembolism prophylaxis: do trial results enable clinicians and patients to evaluate whether the benefits justify the risk? Proceedings of an Ad Hoc Working Group Meeting Academic Article
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Venous thromboembolism, age and hospitalisation: A potentially deadly combination Academic Article
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Venous thromboembolism: Past, present and future Academic Article
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Venous thrombosis in children Academic Article
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Verapamil following uncomplicated myocardial infarction: Promising, but not proven Academic Article
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Vitamin A sensitivity. Academic Article
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Vitamin D supplementation in children with asthma: a systematic review and meta-analysis Academic Article
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Vitamin D supplementation in primary allergy prevention: Systematic review of randomized and non‐randomized studies Academic Article
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Von Willebrand factor and thrombin activation in children with newly diagnosed acute lymphoblastic leukemia: An impact of peripheral blasts Academic Article
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WORK-SITE TREATMENT OF HYPERTENSION BY SPECIALLY TRAINED NURSES Academic Article
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Waiving confidentiality for the greater good Academic Article
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Warfarin Sodium versus Low-Dose Heparin in the Long-Term Treatment of Venous Thrombosis Academic Article
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Weaning from mechanical ventilation: the evidence from clinical research. Academic Article
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What Does the Evidence Tell Us About Design of Future Treatment Trials for Whiplash-Associated Disorders? Academic Article
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What Is Involved in a Regulatory Trial Investigating a New Medical Device? Academic Article
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What do the results of the PRoFESS trial teach us? Academic Article
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What does it take to put an ugly fact through the heart of a beautiful hypothesis? Academic Article
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What happens to intimate partner violence studies registered on clinicaltrials.gov? A systematic review of a clinical trials registry Academic Article
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What have we learnt about asthma control from trials of budesonide/formoterol as maintenance and reliever? Academic Article
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What is a cure and how do we get there? Academic Article
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What is the most valid comparison treatment in trials of intrauterine insemination, timed or uninfluenced intercourse? A systematic review and meta-analysis of indirect evidence Academic Article
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What is the role of invasive versus non-invasive coronary angiography in the investigation of patients suspected to have coronary heart disease? Academic Article
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When is a meta-analysis conclusive? A guide to Trial Sequential Analysis with an example of remote ischemic preconditioning for renoprotection in patients undergoing cardiac surgery Academic Article
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Which cancer clinical trials should be considered for economic evaluation? Selection criteria from the National Cancer Institute of Canada's Working Group on Economic Analysis. Academic Article
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Who is fooling us? Academic Article
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Who says “no” to participating in stroke clinical trials and why: an observational study from the Vancouver Stroke Program Academic Article
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Who should participate in clinical trials and who not? Can clinical trials be made more efficient and effective? Academic Article
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Why do we need some large, simple randomized trials? Academic Article
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Why would a sane clinician not prescribe prophylactic indomethacin? Academic Article
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Ximelagatran: the first oral direct thrombin inhibitor Academic Article
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Ximelagatran: the first oral direct thrombin inhibitor. Academic Article
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Yttrium 90 ibritumomab tiuxetan in lymphoma Academic Article
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Zoledronic acid in the treatment of hypercalcemia of malignancy: Results of the international clinical development program Academic Article
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Zoledronic acid use in cancer patients Academic Article
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[After the HOPE Study. ACE inhibitor now for every diabetic patient?. Interview by Dr. Dirk Einecke]. Academic Article
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[Antithrombotic treatment of atrial fibrillation]. Academic Article
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[Effect of atenolol on the QT interval in the acute phase of myocardial infarction]. Academic Article
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[Four numbers and basic knowledge of mathematics]. Academic Article
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[More fetal monitoring, more cesarean sections? An attempt at meta-analysis of the problem]. Academic Article
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[Non invasive mechanical ventilation in acute cardiogenic pulmonary edema: is it all done?]. Academic Article
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[The number needed to treat (NNT) and the number needed to harm (NNH)]. Academic Article
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[Why bother with regression models?]. Academic Article
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pH, healing rate and symptom relief in acid-related diseases. Academic Article
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pH, healing rate, and symptom relief in patients with GERD. Academic Article
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Ácido tranexâmico no tratamento da hemorragia no trauma Academic Article
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‘Selective dorsal rhizotomy studies’ Academic Article
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“Pragmatic” clinical trials: from whose perspective? Academic Article
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“Therapeutic Range” for Oral Anticoagulant Therapy Academic Article