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Cardiovascular safety of nintedanib in subgroups...
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Cardiovascular safety of nintedanib in subgroups by cardiovascular risk at baseline in the TOMORROW and INPULSIS trials

Abstract

Nintedanib is a tyrosine kinase inhibitor used to treat idiopathic pulmonary fibrosis (IPF). We investigated the cardiovascular safety of nintedanib using pooled data from the TOMORROW and INPULSIS trials.Cardiovascular events were assessed post hoc in patients with a history of atherosclerotic cardiovascular disease (CVD) and/or one or more cardiovascular risk factors at baseline ("higher cardiovascular risk") and patients with no history of …

Authors

Noth I; Wijsenbeek M; Kolb M; Bonella F; Moros L; Wachtlin D; Corte TJ

Volume

54

Publisher

European Respiratory Society (ERS)

Publication Date

9 2019

DOI

10.1183/13993003.01797-2018

Conference proceedings

European Respiratory Journal

Issue

3

ISSN

0903-1936