Journal article
Investigating clinical heterogeneity in systematic reviews: a methodologic review of guidance in the literature
Abstract
BackgroundWhile there is some consensus on methods for investigating statistical and methodological heterogeneity, little attention has been paid to clinical aspects of heterogeneity. The objective of this study is to summarize and collate suggested methods for investigating clinical heterogeneity in systematic reviews.MethodsWe searched databases (Medline, EMBASE, CINAHL, Cochrane Library, and CONSORT, to December 2010) and reference lists and …
Authors
Gagnier JJ; Moher D; Boon H; Beyene J; Bombardier C
Journal
BMC Medical Research Methodology, Vol. 12, No. 1,
Publisher
Springer Nature
Publication Date
12 2012
DOI
10.1186/1471-2288-12-111
ISSN
1471-2288