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Biosimilars for psoriasis: clinical studies to...
Journal article

Biosimilars for psoriasis: clinical studies to determine similarity

Abstract

Biosimilars are drugs that are similar, but not identical, to originator biologics. Preclinical analytical studies are required to show similarity on a molecular and structural level, but efficacy and safety studies in humans are essential to determining biosimilarity. In this review, written by members of the International Psoriasis Council, we discuss how biosimilars are evaluated in a clinical setting, with emphasis on extrapolation of …

Authors

Blauvelt A; Puig L; Chimenti S; Vender R; Rajagopalan M; Romiti R; Skov L; Zachariae C; Young H; Prens E

Journal

British Journal of Dermatology, Vol. 177, No. 1, pp. 23–33

Publisher

Oxford University Press (OUP)

Publication Date

7 2017

DOI

10.1111/bjd.15067

ISSN

0007-0963