Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: Report of a Task Force at the 13th International Congress on Antiphospholipid Antibodies Academic Article uri icon

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  • The antiphospholipid syndrome (APS) is defined by the presence of thrombosis and/or pregnancy morbidity in combination with the persistent presence of circulating antiphospholipid antibodies: lupus anticoagulant, anticardiolipin antibodies and/or anti-β2-glycoprotein I antibodies in medium to high titers. The management of thrombosis in patients with APS is a subject of controversy. This set of recommendations is the result of an effort to produce guidelines for therapy within a group of specialist physicians in Cardiology, Neurology, Hematology, Rheumatology and Internal Medicine, with a clinical and research focus on APS.


  • Ruiz-Irastorza, G
  • Cuadrado, MJ
  • Ruiz-Arruza, I
  • Brey, R
  • Crowther, Mark
  • Derksen, R
  • Erkan, D
  • Krilis, S
  • Machin, S
  • Pengo, V
  • Pierangeli, S
  • Tektonidou, M
  • Khamashta, M

publication date

  • February 2011

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