Efficacy of progesterone support in the luteal phase following in-vitro fertilization and embryo transfer: meta-analysis of clinical trials

The question of whether follicular aspiration of oocytes alters the quality of the luteal phase remains unanswered. Progesterone appears to be necessary for implantation and maintenance of an early intrauterine pregnancy and this partly has been the basis for recommending luteal phase supplementation with progesterone following oocyte retrieval. Although small increases in pregnancy rates were observed in several trials, such support with …