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Loss to follow-up in orthopaedic clinical trials:...
Journal article

Loss to follow-up in orthopaedic clinical trials: a systematic review

Abstract

PurposeThe rate of patients lost to follow-up may contribute to bias in randomized controlled trials (RCTs).MethodsWe systematically reviewed orthopaedic RCTs from 2008 to 2011, including 559 RCTs with 131,836 enrolled subjects. The loss to follow-up rates and minimum follow-up times were recorded for each trial. Orthopaedic subspecialty, country of origin, number of enrolled patients, patient age, follow-up strategy, and funding type were also …

Authors

Somerson JS; Bartush KC; Shroff JB; Bhandari M; Zelle BA

Journal

International Orthopaedics, Vol. 40, No. 11, pp. 2213–2219

Publisher

Springer Nature

Publication Date

November 2016

DOI

10.1007/s00264-016-3212-5

ISSN

0341-2695