Helicobacter pylori Eradication: A Critical Appraisal and Current Concerns

Helicobacter pylori is now well recognized as a critical factor in the majority of patients with peptic ulcer disease and successful treatment of the infection results in cure of the disease. However, treatment of this infection has proved difficult, involving a combination of drugs, and has usually involved complex treatment regimens. Triple therapy involving a bismuth compound in combination with metronidazole and tetracycline or amoxicillin …