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Reassessing Quality-of-Life Instruments in the...
Journal article

Reassessing Quality-of-Life Instruments in the Evaluation of New Drugs

Abstract

Investigators use 2 fundamental approaches to the measurement of health-related quality of life (HR-QOL). Generic instruments include health profiles that tap into the full range of HR-QOL issues and are widely applicable, but may lack responsiveness to small but important changes in HR-QOL. Utility measures summarise HR-QOL in a single number between 0 (death) and 1 (full health) and are useful for economic analysis, but may lack …

Authors

Guyatt GH; Jaeschke RJ

Journal

PharmacoEconomics, Vol. 12, No. 6, pp. 621–626

Publisher

Springer Nature

Publication Date

12 1997

DOI

10.2165/00019053-199712060-00002

ISSN

1170-7690