Journal article
Integrating Mortality and Morbidity Outcomes
Abstract
RATIONALE: Outcome measures that integrate mortality and morbidity, like quality-adjusted life years (QALYs), have been proposed for critical care clinical trials.
OBJECTIVES: We sought to describe the distribution of QALYs in critically ill patients and estimate sample size requirements for a hypothetical trial using QALYs as the primary outcome.
Authors
Ferguson ND; Scales DC; Pinto R; Wilcox ME; Cook DJ; Guyatt GH; Schünemann HJ; Marshall JC; Herridge MS; Meade MO
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 187, No. 3, pp. 256–261
Publisher
American Thoracic Society
Publication Date
February 1, 2013
DOI
10.1164/rccm.201206-1057oc
ISSN
1073-449X