Journal article
Sample Size in the Planning and Interpretation of Clinical Trials
Abstract
An understanding of sample size determination is important in both planning and interpreting the results of clinical trials. A Type II error occurs when it is concluded that there is no difference between treatment groups, when in truth there is a difference. Such a false negative conclusion results from too few patients in a trial. In this review the principles of estimating sample size before a trial is commenced and evaluating the results of …
Authors
levine MN; Hirsh J
Journal
Thrombosis and Haemostasis, Vol. 58, No. 04, pp. 953–956
Publisher
Thieme
Publication Date
1987
DOI
10.1055/s-0038-1646033
ISSN
0340-6245