Journal article
Cyclooxygenase-2 Inhibitors
Abstract
BACKGROUND AND SUMMARY: Selective cyclooxygenase (COX)-2 inhibitors are increasingly being used in place of "conventional" nonsteroidal anti-inflammatory drugs (NSAIDs). This is because they are just as effective as NSAIDs in relieving arthritic pain and yet less gastrotoxic. However, the cardiovascular safety of selective COX-2 inhibitors has been questioned because they selectively reduce prostacyclin production, thus disrupting the normal …
Authors
Hankey GJ; Eikelboom JW
Journal
Stroke, Vol. 34, No. 11, pp. 2736–2740
Publisher
Wolters Kluwer
Publication Date
November 2003
DOI
10.1161/01.str.0000097301.50041.6e
ISSN
0039-2499