Journal article
Treatment of geographic atrophy: an update on data related to pegcetacoplan
Abstract
PURPOSE OF REVIEW: Geographic atrophy is an advanced and currently untreatable form of age-related macular degeneration (AMD), which leads to significant compromise of visual function and quality of life. Dysregulation of the complement cascade has been directly implicated in AMD pathogenesis. Pegcetacoplan is a pegylated highly selective bicyclic peptide that inhibits the cleavage of complement component 3 (C3), which represents a key step in …
Authors
Patel SB; Heier JS; Chaudhary V; Wykoff CC
Journal
Current Opinion in Ophthalmology, Vol. 35, No. 1, pp. 64–72
Publisher
Wolters Kluwer
Publication Date
1 2024
DOI
10.1097/icu.0000000000000845
ISSN
1040-8738