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The credibility of subgroup analyses reported in...
Journal article

The credibility of subgroup analyses reported in stroke trials is low: A systematic review

Abstract

BACKGROUND: Subgroup analyses are widely used to evaluate the heterogeneity of treatment effects in randomized clinical trials. However, there is a limited investigation of the quality of prespecified and reported subgroup analyses in stroke trials. This study evaluated the credibility of subgroup analyses in stroke trials. METHODS AND ANALYSIS: We searched Medline/PubMed, Embase, the Cochrane Central Register of Controlled Trials, and the Web …

Authors

Ademola A; Thabane L; Adekanye J; Okikiolu A; Babatunde S; Almekhlafi MA; Menon BK; Hill MD; Hildebrand KA; Sajobi TT

Journal

International Journal of Stroke, Vol. 18, No. 10, pp. 1161–1168

Publisher

SAGE Publications

Publication Date

December 2023

DOI

10.1177/17474930231168517

ISSN

1747-4930