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A Randomized Controlled Trial of a...
Journal article

A Randomized Controlled Trial of a Low-Molecular-Weight Heparin (Enoxaparin) to Prevent Deep-Vein Thrombosis in Patients Undergoing Elective Hip Surgery

Abstract

There is experimental evidence that low-molecular-weight fractions of heparin are as effective as the standard form but cause less bleeding. We therefore performed a double-blind, randomized trial comparing PK10169 low-molecular-weight heparin with placebo for the prevention of venous thrombosis in patients undergoing elective hip surgery. Prophylactic treatment with a fixed dose was begun postoperatively and continued for 14 days. Fifty …

Authors

Turpie AGG; Levine MN; Hirsh J; Carter CJ; Jay RM; Powers PJ; Andrew M; Hull RD; Gent M

Journal

The New England Journal of Medicine, Vol. 315, No. 15, pp. 925–929

Publisher

Massachusetts Medical Society

Publication Date

October 9, 1986

DOI

10.1056/nejm198610093151503

ISSN

0028-4793