selected scholarly activity
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chapters
- Difficult To Treat Asthma Clinical Essentials Foreword. VII-VIII. 2020
- Asthma. 308-319. 2019
- Asthma. 183-191. 2017
- Clinical Asthma. 65-70. 2014
- Inhaled β2-Agonists. 1534-1541. 2014
- Inhaled Corticosteroids: Clinical Effects in Asthma and COPD. 38-52. 2012
- Assessment of Responses of the Airways to Therapeutic Agents. Lung Biology in Health and Disease. 100-119. 2010
- Asthma Pathogenesis. 893-919. 2009
- Mechanisms and Management of Exercise-Induced Bronchoconstriction. 171-186. 2009
- Prostanoids. 275-282. 2009
- Prostanoids. 277-282. 2009
- Prostanoids. 275-282. 2008
- Asthma. 245-255. 2008
- Cellular and Mediator Mechanisms of the Early-Phase Response. 375-387. 2006
- Chapter 22 Cellular and Mediator Mechanisms of the Early-Phase Response. 375-387. 2006
- Chapter 81 Experimental Models of Airway Hyperresponsiveness. 1403-xvii. 2005
- Experimental Models of Airway Hyperresponsiveness. 1403-1414. 2005
- Cough and Airway Hyperresponsiveness. 115-123. 2003
- Prostanoids. 221-226. 2002
- Inflammatory Mechanisms in Airway Hyperresponsiveness. 1273-1281. 2000
- Prostaglandins and Thromboxane. 269-280. 1998
- Ozone-Induced Bronchial Hyperreactivity. 95-119. 1996
- Inhaled corticosteroid prophylaxis for exercise induced bronchoconstriction. Clinical Respiratory Journal.
- Long-acting beta2-agonists for chronic obstructive pulmonary disease: serious adverse events
-
conferences
- Burden of chronic dry and productive cough on social participation, healthcare resource utilisation and activities of daily living from the Canadian Longitudinal Study on Aging (CLSA). European Respiratory Journal. 2023
- Demographics and subjective cough outcomes of guideline-based treatment in the McMaster Cough Clinic.. European Respiratory Journal. 2023
- Efficacy and safety of gefapixant for treatment of refractory or unexplained chronic cough: a systematic review and dose-response meta-analysis. European Respiratory Journal. 2023
- Eosinophil phenotypes in circulation and airways of asthmatics after inhaled allergen challenge.. European Respiratory Journal. 2023
- Non-T2 cytokines post Benralizumab associate with residual symptoms. European Respiratory Journal. 2023
- Relationship between measures of type II inflammation and patient reported cough severity and quality of life outcomes in patients with chronic cough. European Respiratory Journal. 2023
- Relationship between subjective cough outcomes and activity impairment in patients with chronic cough. European Respiratory Journal. 2023
- Surface receptor expression on circulating and airway eosinophils after inhaled allergen challenge. European Respiratory Journal. 2023
- Work productivity and activity impairment among chronic cough patients after a guideline-based treatment in the McMaster Cough Clinic. European Respiratory Journal. 2023
- Effect of Tezepelumab on Airway Hyperresponsiveness by Baseline Blood Eosinophil Count in Patients With Severe, Uncontrolled Asthma in the Phase 2 CASCADE Study. American Journal of Respiratory and Critical Care Medicine. 2023
- Impact of Productive and Dry Chronic Cough on Mortality in the Canadian Longitudinal Study on Aging (CLSA). American Journal of Respiratory and Critical Care Medicine. 2023
- Alarmin Expression in the Upper and Lower Airways of Asthmatics with Allergic Rhinitis. European Respiratory Journal. 2022
- Benralizumab attenuates blood and airway eosinophilia in severe asthmatics with inadequate response to anti-IL-5 neutralizing antibodies. European Respiratory Journal. 2022
- Capsaicin evoked cough responses and the effect of sex hormones. European Respiratory Journal. 2022
- Impact of mental health and personality traits on the incidence of chronic cough in the Canadian Longitudinal Study on Aging (CLSA). European Respiratory Journal. 2022
- Language and geographical location influences the incidence of chronic cough in the Canadian Longitudinal Study on Aging (CLSA). 05.02 - Monitoring airway disease. 231. 2022
- Reduced ACE2 and TMPRSS2 immunopositive bronchial cells in asthmatics after inhaled allergen challenge. European Respiratory Journal. 2022
- Diabetes Mellitus: Contribution to Pulmonary Impairment and Disability. American Journal of Respiratory and Critical Care Medicine. 2022
- Neuromedin U Stimulates Rapid Activation of Type 2 Innate Lymphoid Cells from Mild Asthmatic Subjects. American Journal of Respiratory and Critical Care Medicine. 2022
- Effects of Traffic-Related Air Pollution on Exercise Endurance, Dyspnea, and Cardiorespiratory Responses in Health and COPD. Chest. 662-675. 2022
- Airway Hyperresponsiveness and Eosinophilic Airway Inflammation In Patients With Atopic Dermatitis. Journal of Allergy and Clinical Immunology. AB14-AB14. 2022
- Effect Of Benralizumab On Skin Responses To Intradermal Allergen Challenge In Patients With Moderate-To-Severe Atopic Dermatitis. Journal of Allergy and Clinical Immunology. AB322-AB322. 2022
- An electronic patient decision aid comparing as-needed budesonide-formoterol combination to regular use of inhaled corticosteroid (ICS) in mild asthma: a rapid-cycle design study. European Respiratory Journal. 2021
- Prevalence, incidence, and characteristics of chronic cough among adults from the canadian longitudinal study on ageing (CLSA). European Respiratory Journal. 2021
- A decision aid to drive adherence to controller treatments in mild asthma: A rapid-cycle design study. Pharmacoepidemiology and Drug Safety. 123-123. 2021
- Comparison of the Capsaicin-Evoked Cough Responses with Histamine-Induced Itch and Wheal Responses in Atopic Asthma. Lung. 429-429. 2021
- Efficacy and Safety of As-Needed Budesonide-Formoterol in Adolescents with Mild Asthma. Journal of Allergy and Clinical Immunology: In Practice. 3069-3077.e6. 2021
- Exercise Induced Bronchoconstriction and Bronchodilation; Investigating the Effects of Age, Sex, Airflow Limitation and the Forced Expired Volume over one Second (FEV1). American Journal of Respiratory and Critical Care Medicine. 2021
- The Sputum Transcriptome of Mild Atopic Asthma Following Bronchoprovocation and Inhaled Anti-TSLP Antibody Fragment Treatment. American Journal of Respiratory and Critical Care Medicine. 2021
- Triple (ICS/LABA/LAMA) vs. Dual (ICS/LABA) Therapy for Persistent, Uncontrolled Asthma: A Systematic Review and Meta-Analysis. American Journal of Respiratory and Critical Care Medicine. 2021
- AS-NEEDED BUDESONIDE-FORMOTEROL EFFICACY AND SAFETY IN ADOLESCENTS WITH MILD ASTHMA. Respirology. 76-76. 2021
- Efficacy of CSJ117 on allergen-induced asthmatic response in mild atopic asthma patients. Pneumologie. S33-S33. 2021
- NNT TO PREVENT ONE EXACERBATION WITH AS-NEEDED BUDESONIDE-FORMOTEROL. Respirology. 81-81. 2021
- Accumulation of Allergen-specific CD4+ T cells in the Airways after Segmental Allergen Challenge is Associated with Reduced Expression of T2 Chemoattractant Receptors on Allergen-specific CD4+ T cells in Blood. Journal of Allergy and Clinical Immunology. AB236-AB236. 2021
- Prednisolone Treatment Reduces Type 2 Inflammation In Skin Lesions Of Patients With Atopic Dermatitis. Journal of Allergy and Clinical Immunology. AB35-AB35. 2021
- The Effect of Benralizumab On Allergen-Induced Responses In Subjects With Mild Allergic Asthma. Journal of Allergy and Clinical Immunology. AB157-AB157. 2021
- Efficacy of as-needed budesonide/formoterol in mild asthma: pooled analysis of SYGMA 1 and 2. European Respiratory Journal. 2020
- Late Breaking Abstract - Efficacy of CSJ117 on allergen-induced asthmatic responses in mild atopic asthma patients. European Respiratory Journal. 2020
- Effect of Intranasal Corticosteroid Treatment on Allergen Induced Changes in Numbers, Activation and Phenotype of Group 2 Innate Lymphoid Cells in Mild Allergic Rhinitics with Asthma. American Journal of Respiratory and Critical Care Medicine. 2020
- Efficacy and Safety of an Inhaled Anti-TSLP Antibody Fragment in Adults with Mild Atopic Asthma. American Journal of Respiratory and Critical Care Medicine. 2020
- Evaluation of the Reproducibility of Nasal Allergen Challenge in Mild Allergic Asthmatics to Support Drug Development. American Journal of Respiratory and Critical Care Medicine. 2020
- Investigating the Repeatability of Cough Endpoints from the Mannitol Inhalation Cough Challenge (MICC). American Journal of Respiratory and Critical Care Medicine. 2020
- Mannitol Evoked Cough Responses; Evidence of Neuronal Dysfunction in Allergic Asthmatics and Females. American Journal of Respiratory and Critical Care Medicine. 2020
- TL1A/DR3 Axis Promotes Group 2 Innate Lymphocyte Activation in Eosinophilic Asthmatics. American Journal of Respiratory and Critical Care Medicine. 2020
- The Effect of Nebulized Salbutamol on Mannitol Evoked Cough Responses in Mild Allergic Asthmatics: A Double-Blind Randomized Placebo Controlled 2-Way Cross-Over Study. American Journal of Respiratory and Critical Care Medicine. 2020
- Exacerbation risk after night-time waking due to asthma in SYGMA 1. European Respiratory Journal. 2019
- Number needed to treat (NNT) to have an additional patient free from a severe or moderate/severe exacerbation: post-hoc analysis of SYGMA 1 in mild asthma. European Respiratory Journal. 2019
- Comparison of responses to nasal and whole lung allergen challenges in mild allergic asthmatic subjects with allergic rhinitis. Allergy. European Journal of Allergy and Clinical Immunology. 462-463. 2019
- The effect of steroid treatment on eosinophil progenitors, eosinophils and basophils in the skin of patients with moderate-to-severe atopic dermatitis. Allergy. European Journal of Allergy and Clinical Immunology. 575-576. 2019
- Type 2 innate lymphoid cells (ILC2s) are reduced in lesional skin biopsies from subjects with atopic dermatitis (AD) following treatment with oral corticosteroids. Allergy. European Journal of Allergy and Clinical Immunology. 579-580. 2019
- Asthma, COPD, Respiratory Infections and Viruses: Admission Rates, ER Visits and Age. American Journal of Respiratory and Critical Care Medicine. 2019
- Efficacy of As-Needed Budesonide/Formoterol for Reducing Severe Exacerbations in Adolescents with Mild Asthma: Pooled Subgroup Analysis of the SYGMA 1 and 2 Trials. American Journal of Respiratory and Critical Care Medicine. 2019
- Influence of Prior Treatment Upon the Efficacy of As-Needed Budesonide/Formoterol in Mild Asthma in the SYGMA 1 and 2 Studies. American Journal of Respiratory and Critical Care Medicine. 2019
- Pulmonary Function in Patients with Congenitial Heart Disease. American Journal of Respiratory and Critical Care Medicine. 2019
- The Effect of Pulmonary Function, Power and Maximum Power Output on Dyspnoea in a Real-World Cohort. American Journal of Respiratory and Critical Care Medicine. 2019
- Enumeration of IL-17A/F Producing Innate Lymphoid Cells in Subjects with COPD. Journal of Allergy and Clinical Immunology. AB218-AB218. 2019
- Sex Differences in Type 2 Innate Lymphoid Cells in Adult Asthmatics. Journal of Allergy and Clinical Immunology. AB1-AB1. 2019
- Short Course Of Oral Prednisolone Improves Physician Reported Clinical Scores and Patient Reported Outcomes in Patients with Moderate-to-Severe Atopic Dermatitis. Journal of Allergy and Clinical Immunology. AB134-AB134. 2019
- Late Breaking Abstract - Risk of a severe exacerbation following higher reliever use: post-hoc analysis of SYGMA 1 in mild asthma. European Respiratory Journal. 2018
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The effects of a
CCR 3 inhibitor,AXP 1275, on allergen‐induced airway responses in adults with mild‐to‐moderate atopic asthma. Clinical and Experimental Allergy. 445-451. 2018 - Elevated Eosinophil Lineage-Committed Progenitors In Skin Lesions Of Patients With Moderate-To-Severe Atopic Dermatitis. Journal of Allergy and Clinical Immunology. AB92-AB92. 2018
- Expression profile of IL-33/ST2 and TSLP/TSLP-R in the skin of atopic dermatitis post-allergen exposure. Journal of Allergy and Clinical Immunology. AB187-AB187. 2018
- Type 2 Innate Lymphoid Cells and Eosinophil Progenitor Cells are Preferentially Increased in Lesional Skin of Subjects with Atopic Dermatitis. Journal of Allergy and Clinical Immunology. AB293-AB293. 2018
- Type 2 innate lymphoid cells expressing death receptor 3 are increased in airway of mild atopic asthmatic subject following allergen inhalation challenge. Journal of Allergy and Clinical Immunology. AB285-AB285. 2018
- Interleukin-25 and Eosinophils Progenitor Cell Mobilization in Allergic Asthma. American Journal of Respiratory and Critical Care Medicine. 2018
- Investigating Airway Reflexes by Assessing Capsaicin Evoked Cough Responses in an Allergen Challenge Model of Asthma. American Journal of Respiratory and Critical Care Medicine. 2018
- Severe Exacerbations and Inhaled Corticosteroid Load with As-Needed Budesonide/Formoterol vs Maintenance Budesonide in Mild Asthma. American Journal of Respiratory and Critical Care Medicine. 2018
- Sputum Eosinophils, Neutrophils, Bronchoconstriction Following Inhaled Allergen. American Journal of Respiratory and Critical Care Medicine. 2018
- A study to assess airway remodelling and the utility of low dose CT scoring to evaluate the asthmatic airway. Irish Journal of Medical Science. S420-S420. 2017
- A study to assess airway remodelling and the utility of low dose CT scoring to evaluate the asthmatic airway. Irish Journal of Medical Science. S420-S420. 2017
- A study to define the microbiome of the asthmatic airway. Irish Journal of Medical Science. S430-S430. 2017
- A study to define the microbiome of the asthmatic airway. Irish Journal of Medical Science. S430-S430. 2017
- An investigation into adult asthmatic asthma to define the microbiome subtypes present. Irish Journal of Medical Science. S429-S429. 2017
- An investigation into adult asthmatic asthma to define the microbiome subtypes present. Irish Journal of Medical Science. S429-S429. 2017
- Detecting the presence of Aspergillus in the asthmatic airway and its relationship to disease severity. Irish Journal of Medical Science. S420-S420. 2017
- A study to assess airway remodelling and the utility of low dose CT scoring to evaluate the asthmatic airway. European Respiratory Journal. 2017
- A study to define microbiome subtypes in the adult asthmatic airway. European Respiratory Journal. 2017
- A study to define the microbiome of the asthmatic airway. European Respiratory Journal. 2017
- Presence of Aspergillus in the asthmatic airway and its relationship to disease severity. Clinical Problems Asthma. pa653. 2017
- Airway Levels Of Cx3cl1 Are Increased In Subjects With Asthma Compared To COPD And Normal Controls. American Journal of Respiratory and Critical Care Medicine. 2017
- Airway Response To House Dust Mite Allergen Bronchial Challenge In Allergic Asthma. American Journal of Respiratory and Critical Care Medicine. 2017
- Asthma, Chronic Obstructive Pulmonary Disease, Respiratory Tract Infections And Viruses: Admission Rates, Emergency Room Visits And Age. American Journal of Respiratory and Critical Care Medicine. 2017
- Expression Profile Of Interleukin-33 (il-33), Interleukin-1 Receptor Family Member (il1rl1, St2) And Thymic Stromal Lymphopoietin (tslp) In Airway Epithelium From Asthmatic Subjects After Allergen Challenge. American Journal of Respiratory and Critical Care Medicine. 2017
- Multi-Omic Biomarker Signatures Are Predictive Of The Allergen-Induced Late Phase Asthmatic Response. American Journal of Respiratory and Critical Care Medicine. 2017
- Peroxidation Of Phosphatidylcholine: A Signature For Allergen-Induced Airway Responses And Allergen Specificity. American Journal of Respiratory and Critical Care Medicine. 2017
- Rates Of Hospital Admission And Emergency Room Visits With Asthma, Chronic Obstructive Pulmonary Disease, And Respiratory Tract Infection Relative To Age And Season In Ontario, Canada. American Journal of Respiratory and Critical Care Medicine. 2017
- Type 2 Innate Lymphoid Cells Up-Regulate Dr3 Expression Upon Stimulation With Il-2. American Journal of Respiratory and Critical Care Medicine. 2017
- P134 Methacholine challenge to demonstrate therapeutic equivalence of terbutaline via different turbuhaler devices in patients with mild to moderate asthma: appraisal of a phase iii, four-way crossover design. Thorax. A155.2-A155. 2016
- IL-33 and its Receptor ST2 in Patients with Allergic Asthma Before and After Inhaled Allergen Challenge. Irish Journal of Medical Science. S455-S455. 2016
- The Role of Glucagon Like Peptide-1 and its Receptor in Allergic Asthma. Irish Journal of Medical Science. S478-S478. 2016
- LSC Abstract – Systems approach to predict asthmatic response to allergen inhalation challenge. European Respiratory Journal. 2016
- Mepolizumab in COPD with eosinophilic bronchitis: A randomized clinical trial. European Respiratory Journal. 2016
- Allergen-Induced Increase in Group 2 Innate Lymphoid Cells in the Airways of Mild Asthmatics. Journal of Allergy and Clinical Immunology. AB178-AB178. 2016
- Human Hemopoietic Progenitor Cell Toll-like and Thymic Stromal Lymphopoietin Receptor Expression and Function in Allergic Asthmatic Subjects. Journal of Allergy and Clinical Immunology. AB73-AB73. 2016
- Mepolizumab in COPD with Eosinophilic Bronchitis: A Randomized Clinical Trial. Journal of Allergy and Clinical Immunology. AB392-AB392. 2016
- 2-Minute Tidal Breathing Methacholine Challenge: Comparison Of Two Jet Nebulizers. American Journal of Respiratory and Critical Care Medicine. 2016
- Bronchial Epithelial Cells Expression Of Il-17a And Il-17f In Asthma And COPD. American Journal of Respiratory and Critical Care Medicine. 2016
- Comparison Of Il-17a And Il-17f Cytokine-Expression In Cd4+Lymphocytes Between Asthma, COPD And Healthy Subjects. American Journal of Respiratory and Critical Care Medicine. 2016
- The Expression Of The Interleukin-33 Receptor St2l On Eosinophils Following Bronchial Allergen Challenge In Allergic Asthma Subjects. American Journal of Respiratory and Critical Care Medicine. 2016
- LATE-BREAKING ABSTRACT: A novel role for CCR3 in promoting airways hyperreactivity; Role for CCR3-muscarinic M3 receptor heterodimers. European Respiratory Journal. 2015
- QGE031 (ligelizumab) is more effective than omalizumab and placebo in inhibiting allergen-induced early asthmatic response: Results from a predictive modeling study. European Respiratory Journal. 2015
- The dynamic change of IL-25 and its receptor expression during allergen challenge in asthmatic subjects. European Respiratory Journal. 2015
- A Predictive Model For Determining The Efficacy Of Multiple Doses Of Qge031 (ligelizumab) Versus Omalizumab And Placebo In Inhibiting The Allergen-Induced Early Asthmatic Response. American Journal of Respiratory and Critical Care Medicine. 2015
- Efficacy And Safety Of A Cxcr2 Antagonist, Azd5069, In Severe, Uncontrolled Persistent Asthma. American Journal of Respiratory and Critical Care Medicine. 2015
- Generation And Immunophenotypic Characterization Of Dendritic Cells From Bone Marrow-Derived Cd34+Cells From Asthmatic Subjects. American Journal of Respiratory and Critical Care Medicine. 2015
- Il-25 Receptor And Toll-Like Receptor 9 Expression By Plasmacytoid Dendritic Cells After Allergen Challenge In Allergic Asthmatics. American Journal of Respiratory and Critical Care Medicine. 2015
- Low-Dose Budesonide Treatment Improves Lung Function In Patients With Infrequent Asthma Symptoms At Baseline: A Post-Hoc Analysis Of The Start Study. American Journal of Respiratory and Critical Care Medicine. 2015
- Low-Dose Budesonide Treatment Reduces Severe Asthma-Related Events In Patients With Infrequent Asthma Symptoms At Baseline: A Post-Hoc Analysis Of The Start Study. American Journal of Respiratory and Critical Care Medicine. 2015
- Molecular Biomarkers Of Atopic Asthma In Blood And Sputum. American Journal of Respiratory and Critical Care Medicine. 2015
- Natural T Regulatory Cells In Healthy And Asthmatic Subjects - Frequency And Function Are Phenotype-Dependent. American Journal of Respiratory and Critical Care Medicine. 2015
- Neuronal Dysfunction In Asthma; Novel Mechanistic Insights From The Study Of Cough. American Journal of Respiratory and Critical Care Medicine. 2015
- P7 Neuronal Dysfunction In Asthma; Insights From The Study Of The Cough Reflex. Thorax. A80-A80. 2014
- Blockade of TSLP pathway alters asthma biomarkers. European Respiratory Journal. 2014
- Blockade of TSLP pathway alters asthma biomarkers. European Respiratory Journal. 2014
- Blood-based molecular biomarkers of allergen-induced early and late asthmatic responses. Allergy. European Journal of Allergy and Clinical Immunology. 60-60. 2014
- Late-breaking abstract: Efficacy and safety of multiple doses of QGEo31 (ligelizumab) versus omalizumab and placebo in inhibiting the allergen induced early asthmatic response. European Respiratory Journal. 2014
- Blood biomarkers of the late phase asthmatic response using RNA-Seq. Genome. 383-383. 2014
- Myeloid dendritic cells type 2 after allergen inhalation in asthmatic subjects. Clinical and Experimental Allergy. 921-929. 2014
- Effects Of Amg 157, An Anti-Thymic Stromal Lymphopoietin Monoclonal Antibody, On Allergen-Induced Early And Late Phase Airway Responses In Subjects With Mild Atopic Asthma. American Journal of Respiratory and Critical Care Medicine. 2014
- Efficacy And Safety Of Once-Daily Fluticasone Furoate/vilanterol (ff/vi) And Ff Over 12 Weeks In Patients With Persistent Asthma. American Journal of Respiratory and Critical Care Medicine. 2014
- Il-25 And Its' Receptor Expression In Blood After Allergen Inhalation Challenge In Mild Asthmatics. American Journal of Respiratory and Critical Care Medicine. 2014
- Invariant Natural Killer Cells In Allergic Asthma. American Journal of Respiratory and Critical Care Medicine. 2014
- Repeated Methacholine Bronchoprovocation Does Not Affect Baseline Fev1. American Journal of Respiratory and Critical Care Medicine. 2014
- The Dose-Response Effect Of Cigarette Smoking On Chronic Airflow Limitation (cal) Prevalence Across The World: The Pure-Breath Study. American Journal of Respiratory and Critical Care Medicine. 2014
- The Global Prevalence Of Dyspnea And Its Contributing Factors: The Pure-Breath Study. American Journal of Respiratory and Critical Care Medicine. 2014
- The Role Of Tslp And Il-33 In The Recruitment Of Eosinophil-Lineage Committed Progenitor Cells To The Airways In Allergen-Induced Asthmatic Responses. American Journal of Respiratory and Critical Care Medicine. 2014
- Myeloid dendritic cells type 2 in allergic asthma. Acta Allergologica. 1322-1326. 2013
- Ease of use of a two-strip dry powder inhaler (DPI) to deliver fluticasone furoate/vilanterol (FF/VI) and FF alone in asthma. European Respiratory Journal. 2013
- Efficacy and safety of once-daily (OD) fluticasone furoate (FF) 50mcg over 24 weeks in adults and adolescents with persistent asthma. European Respiratory Journal. 2013
- Efficacy and safety of once-daily (OD) fluticasone furoate (FF) in adults and adolescents with moderate-to-severe persistent asthma. European Respiratory Journal. 2013
- Efficacy of budesonide/formoterol maintenance and reliever therapy in mild asthma. European Respiratory Journal. 2013
- Magnitude of the late allergen response in seasonal vs perennial allergen bronchoprovocation. European Respiratory Journal. 2013
- Peripheral blood Th17 / Treg ratio increases in late asthmatic response. European Respiratory Journal. 2013
- Effect Of An Inhaled Selective Glucocorticoid Receptor Modulator (azd5423) On Allergen-Induced Airway Responses And Airway Inflammation. American Journal of Respiratory and Critical Care Medicine. 2013
- Effects Of Asm-024, A New Compound With Dual Nicotinic And Muscarinic Activity, On Airway Responsiveness And Allergen-Induced Responses In Mild Asthmatics. American Journal of Respiratory and Critical Care Medicine. 2013
- Efficacy And Safety Of Once-Daily Fluticasone Furoate (ff) 50mcg In Adults With Persistent Asthma. American Journal of Respiratory and Critical Care Medicine. 2013
- Measurement Properties Of An Asthma Symptom And Rescue Medication Use Diary: A Critical Review. American Journal of Respiratory and Critical Care Medicine. 2013
- Differentially Expressed MicroRNAs In Peripheral Blood Of Asthmatics Undergoing Allergen Inhalation Challenge. C67. TRANSLATIONAL 'OMICS' DISCOVERIES IN LUNG DISEASE. a4907-a4907. 2012
- Dose-Finding Study Of Once-Daily Treatment With Olodaterol, A Novel Long-Acting B2-Agonist, In Patients With Asthma. C22. ASTHMA THERAPY. a3963-a3963. 2012
- Effect Of An Anti-M1 Prime Monoclonal Antibody, MEMP1972A, In A Phase II Proof-Of-Activity Allergen Challenge Study In Patients With Mild Asthma. B37. NEW INSIGHTS INTO ASTHMA AND COPD TREATMENT. a6793-a6793. 2012
- Kinetics Of Regulatory T Cells In Induced Sputum Before And After Allergen Challenge In Mild Asthmatics. C21. ASTHMA BIOMARKERS. a3924-a3924. 2012
- Predictors Of Asthma Control And A Risk Score For Exacerbations. D34. ASTHMA EPIDEMIOLOGY. a5667-a5667. 2012
- A Comparison Of Four Flow Cytometric Gating Strategies In The Quantification Of Natural T Regulatory Cells In A Population Of Allergic Asthmatic Subjects. American Journal of Respiratory and Critical Care Medicine. 2011
- Genomic Response Profiles In Peripheral Blood Of Asthmatics Undergoing Allergen Inhalation Challenge Differentiate Isolated Early From Dual Responders. American Journal of Respiratory and Critical Care Medicine. 2011
- IL-18 And IL-18 Receptor Alpha Expression In Allergic Asthma. American Journal of Respiratory and Critical Care Medicine. 2011
- Inhaled Budesonide Induces Corticosteroid-Dependent Gene Expression In Mild Asthmatic Patients: Validation In Primary Human Epithelial And Airways Smooth Muscle Cells. American Journal of Respiratory and Critical Care Medicine. 2011
- Pulmonary Function In Healthy Non-Smoking Adults From 17 Countries In Different Regions Of The World. American Journal of Respiratory and Critical Care Medicine. 2011
- The Effects Of Montelukast, Budesonide Alone And In Combination On Exercise-Induced Bronchoconstriction. A34. MANAGEMENT OF ASTHMA, RHINITIS, AND SINUSITIS. a1381-a1381. 2011
- The Effects Of Montelukast, Budesonide Alone And In Combination On Exercise-Induced Bronchoconstriction, [Publication Page: A1381]. American Journal of Respiratory and Critical Care Medicine. 2011
- PS2-27 Bioactive oncostatin m is present in induced-sputum samples from house dust mite -sensitive asthmatic subjects. Cytokine. 56-56. 2010
- Allergen Induced Reduction In Airway Smooth Muscle Is Attenuated By Budesonide And Formoterol Combination Therapy. American Journal of Respiratory and Critical Care Medicine. 2010
- Can Changes In Sputum Inflammatory Cells Predict The Allergen-induced Airway Hyperresponsiveness In Allergic Asthmatic Subjects?. American Journal of Respiratory and Critical Care Medicine. 2010
- Can Sputum Eosinophils, Neutrophils Or Macrophages Predict The Severity Of Bronchoconstriction Following Allergen Inhalation?. American Journal of Respiratory and Critical Care Medicine. 2010
- Detection Of IL4 Receptor± In Sputum Eosinophils And Macrophage. American Journal of Respiratory and Critical Care Medicine. 2010
- Functional Genomics Of The Asthmatic Response To Allergen Inhalation Challenge. C93. MOLECULAR AND CLINICAL PHENOTYPING OF ASTHMA. a5092-a5092. 2010
- Increased Lung-Homing Of Vascular Endothelial Progenitor Cells In Asthmatic Subjects Following Allergen Inhalation Challenge. American Journal of Respiratory and Critical Care Medicine. 2010
- Patient Baseline Characteristics Predict An Increased Risk Of Future Asthma Exacerbations. C93. MOLECULAR AND CLINICAL PHENOTYPING OF ASTHMA. a5094-a5094. 2010
- Treatment With The CXCR2 Antagonist SCH527123 Reduced Neutrophil Levels In Blood And Airways But Not Bone Marrow In Mild Asthmatic Subjects. C33. ANTI-INFLAMMATORY STRATEGIES IN AIRWAYS DISEASE: ANIMAL MODELS. a4237-a4237. 2010
- A Randomized, Double-Blind, Placebo Controlled Multicenter Study To Evaluate the Efficacy of a Humanized Interleukin-9 Monoclonal Antibody (MEDI-528) on the Late Asthmatic Response in Adults with Atopic Asthma.. American Journal of Respiratory and Critical Care Medicine. 2009
- Airway Neutrophilia after Allergen Challenge in Subjects with Atopic Asthma.. American Journal of Respiratory and Critical Care Medicine. 2009
- GM-CSF Overexpression in the Lung Changes Immune Susceptibility and Responsiveness to House Dust Mite Exposure.. American Journal of Respiratory and Critical Care Medicine. 2009
- Myeloid and Plasmacytoid Dendritic Cells in Sputum Following Allergen Challenge in Allergic Asthmatic Subjects.. American Journal of Respiratory and Critical Care Medicine. 2009
- Safety of Allergen Inhalation Challenge in Allergic Asthmatic Subjects.. American Journal of Respiratory and Critical Care Medicine. 2009
- The effect of C5 inhibition by eculizumab on allergen-induced asthmatic responses. Allergy. European Journal of Allergy and Clinical Immunology. 16-16. 2009
- The effect of IVX‐0142, a heparin‐derived hypersulfated disaccharide, on the allergic airway responses in asthma. Acta Allergologica. 1195-1201. 2008
- A SINGLE DOSE OF MEDI-528, A MONOCLONAL ANTIBODY AGAINST INTERLEUKIN-9, IS WELL TOLERATED IN MILD AND MODERATE ASTHMATICS IN THE PHASE II TRIAL MI-CP-138. Chest. 478A-478A. 2007
- Comparative long-term efficacy of ciclesonide versus a fixed combination of fluticasone propionate and salmeterol in mild persistent asthma. Allergy. European Journal of Allergy and Clinical Immunology. 11-11. 2007
- The effects of inhaled budesonide and formoterol in combination and alone when given directly after allergen challenge. Journal of Allergy and Clinical Immunology. 322-327. 2007
- Regulation Of IL-5Rα On Bone Marrow Eosinophils and CD34+ Progenitors. Journal of Allergy and Clinical Immunology. S252-S252. 2006
- Airway Hyperresponsiveness. Chest. 411S-416S. 2003
- Adding formoterol to budesonide in moderate asthmatics is cost saving - Results from the FACET Study. Journal of Allergy and Clinical Immunology. S109-S109. 2001
- Treatment with IFN gamma reverses airway pathophysiology in allergen-challenged IFN gamma deficient mice. Journal of Allergy and Clinical Immunology. S90-S90. 2001
- Upregulation of eotaxin receptor, CCR3, on bone marrow CD34+progenitor cells following allergen-inhalation challenge in asthmatic subjects: A mechanism of progenitor cell egress from the bone marrow during allergic inflammation. Journal of Allergy and Clinical Immunology. S324-S324. 2001
- 227 Glucocorticoid enhancement of IL-5-induced bone marrow eosinophil progenitor colony formation in vitro. Journal of Allergy and Clinical Immunology. S74-S74. 2000
- 305 A high dose of inhaled budesonide is more cost-effective than a low dose in moderate asthma. Journal of Allergy and Clinical Immunology. S102-S103. 2000
- 521 Increased numbers of eosinophil progenitor cells (CD34+IL5R?+) in the bone marrow of atopic asthmatic subjects. Journal of Allergy and Clinical Immunology. S172-S172. 2000
- Interaction between haemopoietic regulation and airway inflammation. Clinical and Experimental Allergy. 27-32. 1999
- Allergen-induced increase in airway responsiveness, airway eosinophilia and bone marrow eosinophil progenitors in mice.. American Journal of Respiratory and Critical Care Medicine. A870-A870. 1999
- Apoptotic eosinophils in induced sputum after allergen challenge: Effect of fluticasone.. American Journal of Respiratory and Critical Care Medicine. A848-A848. 1999
- Asthma symptoms following low dose allergen exposure. American Journal of Respiratory and Critical Care Medicine. A653-A653. 1999
- Circulating dendritic cells and asthma: Rapid response to inhaled allergen. American Journal of Respiratory and Critical Care Medicine. A854-A854. 1999
- Disruption of reticular basement membrane in mild asthma following allergen challenge. American Journal of Respiratory and Critical Care Medicine. A407-A407. 1999
- Diversity of allergen-induced myofibroblasts in mild asthma. American Journal of Respiratory and Critical Care Medicine. A259-A259. 1999
- Duration of protection by inhaled budesonide on allergen-induced airway responses in atopic asthmatics.. American Journal of Respiratory and Critical Care Medicine. A632-A632. 1999
- Effects of fluticasone on allergen-induced airway responses: Single dose versus two weeks treatment.. American Journal of Respiratory and Critical Care Medicine. A633-A633. 1999
- Effects of fluticasone on allergen-induced inflammation in sputum: Single dose versus two weeks treatment.. American Journal of Respiratory and Critical Care Medicine. A853-A853. 1999
- Effects of inhaled budesonide on airway responses to repeated low dose allergen challenge.. American Journal of Respiratory and Critical Care Medicine. A632-A632. 1999
- Increased IL-5-production by T-cells and non-T-cells in bone-marrow after airway allergen exposure. American Journal of Respiratory and Critical Care Medicine. A98-A98. 1999
- Intracellular cytokines in T-cells from patients with allergic asthma and the effects of inhaled corticosteroids. American Journal of Respiratory and Critical Care Medicine. A103-A103. 1999
- Optimization of sputum fluid phase measurements.. American Journal of Respiratory and Critical Care Medicine. A849-A849. 1999
- Protection against methacholine airway constriction: A valid assessment of bio-equivalence of inhaled beta-2 agonists.. American Journal of Respiratory and Critical Care Medicine. A877-A877. 1999
- Tee costs and effects of adding formoterol to budesonide results from the facet study. American Journal of Respiratory and Critical Care Medicine. A762-A762. 1999
- The effect of inhaled budesonide on baseline and allergen-induced airway inflammatory cells in atopic asthmatics.. American Journal of Respiratory and Critical Care Medicine. A632-A632. 1999
- The effect of inhaled leukotriene D-4 on airway eosinophilia and hyperresponsiveness in asthmatic subjects.. American Journal of Respiratory and Critical Care Medicine. A331-A331. 1999
- Bronchial challenge tests with allergens. ASTHMA - A LINK BETWEEN ENVIRONMENT, IMMUNOLOGY, AND THE AIRWAYS. 221-226. 1999
- Circulating T-cells and granulocytes from asthmatics exhibit impaired capacity for intracellular IL-10 production.. Journal of Allergy and Clinical Immunology. S203-S203. 1999
- Experimental studies on inhaled corticosteroids effects. ASTHMA - A LINK BETWEEN ENVIRONMENT, IMMUNOLOGY, AND THE AIRWAYS. 262-266. 1999
- Regulation of IL–5 and IL–5 Receptor Expression in the Bone Marrow of Allergic Asthmatics. International Archives of Allergy and Immunology. 101-103. 1999
- The effects of inhaled budesonide on eosinophil progenitor cells following allergen inhalation in atopic asthmatics.. Journal of Allergy and Clinical Immunology. S59-S59. 1999
- Effects of inhaled formoterol and budesonide in reducing asthma exacerbations. European Respiratory Review. 221-224. 1998
- Pharmacologic modulation of airway inflammation. Acta Allergologica. 41-47. 1998
- Concluding discussion. European Respiratory Review. 227-228. 1998
- Expression of GM-CSF mRNA and product differentiating eosinophils in vitro.. Journal of Allergy and Clinical Immunology. S222-S222. 1998
- Bone marrow contribution to eosinophilic inflammation. Memorias do Instituto Oswaldo Cruz. 33-35. 1997
- Bone Marrow Progenitors in Allergic Airways Diseases: Studies in Canine and Human Models. International Archives of Allergy and Immunology. 181-183. 1997
- Delivery and the importance of the inhalation device in asthma therapy. European Respiratory Review. 362-365. 1997
- GM-CSF regulation by differentiating eosinophils after allergen challenge.. Journal of Allergy and Clinical Immunology. 1482-1482. 1997
- Increased expression of IL-5 receptor alpha-subunit on bone marrow derived CD34(+) progenitors following allergen challenge in dual responder asthmatics.. Journal of Allergy and Clinical Immunology. 1106-1106. 1997
- Summary: The future promise of mediator inhibitors. European Respiratory Review. 274-277. 1997
- Airway inflammation and asthma.. Alimentary Pharmacology and Therapeutics. 18-24. 1996
- Discussion. European Respiratory Review. 119-120. 1996
- Increased bone marrow progenitor growth after allergen challenge in dogs depends on a serum factor. Journal of Allergy and Clinical Immunology. 458-458. 1996
- Increases in circulating CD34(+) hemopoietic progenitors in allergen-induced late asthmatic responses. Journal of Allergy and Clinical Immunology. 380-380. 1996
- The effects of inhaled prostaglandin E(2) on allergen-induced airway responses. Journal of Allergy and Clinical Immunology. 412-412. 1996
- STIMULATION OF CANINE BONE-MARROW GRANULOCYTE PROGENITOR GROWTH BY A SERUM FACTOR PRESENT 24 HOURS AFTER ALLERGEN INHALATION. Journal of Allergy and Clinical Immunology. 376-376. 1995
- THE ALLERGEN-INDUCED LATE ASTHMATIC RESPONSE AS A MODEL TO TEST RELATIVE POTENCY OF INHALED CORTICOSTEROIDS. Journal of Allergy and Clinical Immunology. 310-310. 1995
- General discussion. Allergy: European Journal of Allergy and Clinical Immunology, Supplement. 110-111. 1993
- General discussion. Allergy: European Journal of Allergy and Clinical Immunology, Supplement. 162-163. 1993
- General discussion. Allergy: European Journal of Allergy and Clinical Immunology, Supplement. 143-145. 1993
- General discussion. Allergy: European Journal of Allergy and Clinical Immunology, Supplement. 84-86. 1993
- General discussion. Allergy: European Journal of Allergy and Clinical Immunology, Supplement. 48-49. 1993
- General discussion. Allergy: European Journal of Allergy and Clinical Immunology, Supplement. 22-23. 1993
- General discussion. Allergy: European Journal of Allergy and Clinical Immunology, Supplement. 62-64. 1993
- Assessing cost‐effectiveness in asthma care: building an economic model to study the impact of alternative intervention strategies. Acta Allergologica. 146-152. 1993
- Cells and mediators in bronchoalveolar lavage of asthmatic patients: the example of eosinophilic inflammation. Acta Allergologica. 70-76. 1993
- Clinical significance of measuring levels of sputum and serum ECP and serum IL‐5 in bronchial asthma. Acta Allergologica. 98-106. 1993
- Functional and phenotypic characteristics of bronchial epithelial cells obtained by brushing from asthmatic and normal subjects. Acta Allergologica. 32-38. 1993
- Impact of monitoring inflammation on the management of adult asthmatic patients. Acta Allergologica. 153-157. 1993
- Pathophysiology of asthma. Acta Allergologica. 50-56. 1993
- The definition and diagnosis of asthma. Acta Allergologica. 12-16. 1993
- T‐cells and endothelial cells in asthma. Acta Allergologica. 24-31. 1993
- AIRWAY CELLULAR COMPOSITION PRIOR TO ALLERGEN INHALATION INFLUENCES THE DEVELOPMENT OF AIRWAY HYPERRESPONSIVENESS IN DOGS. American Review of Respiratory Disease. A857-A857. 1993
- EFFECT OF ALLERGEN INHALATION ON AIRWAY INFLAMMATION AND HYPERRESPONSIVENESS IN DOGS. American Review of Respiratory Disease. A857-A857. 1993
- EFFECTS OF A 5-LIPOXYGENASE ACTIVATING PROTEIN ANTAGONIST (MK-0591) ON OZONE-INDUCED LEUKOTRIENE PRODUCTION AND AIRWAY HYPERRESPONSIVENESS IN DOGS. American Review of Respiratory Disease. A297-A297. 1993
- EFFECTS OF A THROMBOXANE RECEPTOR ANTAGONIST, BAY U3405, ON ALLERGEN-INDUCED ASTHMATIC RESPONSES. American Review of Respiratory Disease. A447-A447. 1993
- EXPRESSION OF GAP JUNCTION PROTEIN CX43 AND MESSENGER-RNA IN CANINE TRACHEAL SMOOTH-MUSCLE, BRONCHUS AND LUNG. American Review of Respiratory Disease. A53-A53. 1993
- GRANULOCYTE MACROPHAGE-COLONY-STIMULATING FACTOR AND EOSINOPHIL CATIONIC PROTEIN IN BRONCHIAL BIOPSIES - COMPARISONS BETWEEN MILD ASTHMATICS AND NON-ASTHMATICS. American Review of Respiratory Disease. A783-A783. 1993
- ASTHMA AS AN INFLAMMATORY DISEASE. International Congress Series. 151-156. 1993
- MEDIATOR INHIBITORS AS NOVEL THERAPEUTIC AGENTS IN ASTHMA. ASTHMA. 407-417. 1993
- THE EFFECTS OF A 5-LIPOXYGENSAE INHIBITOR, ZILEUTON, ON OZONE-INDUCED AIRWAY HYPERRESPONSIVENESS IN DOGS. Journal of Allergy and Clinical Immunology. 161-161. 1993
- CIMETIDINE PREVENTS HISTAMINE TACHYPHYLAXIS IN ASTHMATIC SUBJECTS. Thorax. 748-748. 1987
- INHALED LEUKOTRIENE D4 DOES NOT CAUSE A LATE ASTHMATIC RESPONSE IN ATOPIC SUBJECTS. Journal of Allergy and Clinical Immunology. 141-141. 1987
- ROLE OF THE PARASYMPATHETIC NERVOUS-SYSTEM IN AIRWAY HYPERRESPONSIVENESS AFTER OZONE IN DOGS. American Review of Respiratory Disease. A174-A174. 1986
- IS THROMBOXANE GENERATION IMPORTANT FOR OZONE-INDUCED AIRWAY HYPERRESPONSIVENESS IN DOGS. The FASEB Journal. 614-614. 1985
- RELATIVE POTENCY OF INHALED LEUKOTRIENES-C-4 AND LEUKOTRIENE-D-4 COMPARED WITH METHACHOLINE IN ASTHMATICS AND NORMALS. Thorax. 717-718. 1985
- A MECHANISM FOR AIRWAY HYPERRESPONSIVENESS. Thorax. 706-706. 1984
- PROSTAGLANDIN-E2 MODULATES CHOLINERGIC NEUROTRANSMISSION IN CANINE TRACHEAL MUSCLE. Clinical Science. P23-P24. 1984
- THE RELATIONSHIP BETWEEN NEUTROPHILS AND HYPERRESPONSIVE AIRWAYS. Thorax. 230-230. 1984
- HYPERREACTIVITY AND CHANGES IN CELL COUNTS IN BRONCHOALVEOLAR LAVAGE AFTER OZONE IN DOGS. American Review of Respiratory Disease. 244-244. 1983
- IMPORTANCE OF AIRWAY INFLAMMATION FOR HYPERREACTIVITY INDUCED BY OZONE IN DOGS. The FASEB Journal. 1377-1377. 1983
- THE EFFECT OF INHALED HEXAMETHONIUM AND ATROPINE ON HISTAMINE STIMULATED BRONCHOCONSTRICTION IN ASTHMA. American Review of Respiratory Disease. 250-250. 1983
- THE PROTECTIVE EFFECT OF INHALED CHLORPHENIRAMINE AND ATROPINE ON BRONCHOCONSTRICTION STIMULATED BY AIRWAY COOLING. American Review of Respiratory Disease. 250-250. 1983
- LUNG EPITHELIAL PERMEABILITY AFTER HISTAMINE CHALLENGE. American Review of Respiratory Disease. 280-280. 1982
- LUNG EPITHELIAL PERMEABILITY IN NORMAL SUBJECTS, ASTHMATICS AND SMOKERS. Chest. 253-253. 1982
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journal articles
- Asthma remission. Jornal de Pneumologia. 50:e20240004-e20240004. 2024
- Corrigendum to “Burden of chronic cough on social participation, healthcare resource utilisation and activities of daily living in the Canadian Longitudinal Study on Aging (CLSA)” [Respir. Med. 219 (2013) 107431]. Respiratory Medicine. 223:107556-107556. 2024
- Benralizumab Normalizes Sputum Eosinophilia in Severe Asthma Uncontrolled by Anti–IL-5 Antibodies: A Single-Blind, Placebo-controlled Clinical Trial. American Journal of Respiratory and Critical Care Medicine. 208:1330-1335. 2023
- Burden of chronic cough on social participation, healthcare resource utilisation and activities of daily living in the Canadian Longitudinal Study on Aging (CLSA). Respiratory Medicine. 219:107431-107431. 2023
- Evaluation of the reproducibility of responses to nasal allergen challenge and effects of inhaled nasal corticosteroids. Clinical and Experimental Allergy. 53:1187-1197. 2023
-
Protein expression of
SARS‐CoV ‐2 receptorsACE2 andTMPRSS2 in allergic airways after allergen challenge. Acta Allergologica. 78:3010-3013. 2023 - Efficacy and Tolerability of Gefapixant for Treatment of Refractory or Unexplained Chronic Cough. Journal of the American Medical Association (JAMA). 330:1359-1359. 2023
- Questions in Mild Asthma: An Official American Thoracic Society Research Statement. American Journal of Respiratory and Critical Care Medicine. 207:e77-e96. 2023
- Impact of Airway Virus in Severe Asthmatic Patients: A Pilot Study. Allergy, Asthma and Immunology Research. 15:406-406. 2023
- Inhaled anti-TSLP antibody fragment, ecleralimab, blocks responses to allergen in mild asthma. European Respiratory Journal. 61:2201193-2201193. 2023
- Development of an inhaled anti-TSLP therapy for asthma. Pulmonary Pharmacology and Therapeutics. 78:102184-102184. 2023
- Sounding the alarmins—The role of alarmin cytokines in asthma. Acta Allergologica. 78:402-417. 2023
- Effect of Biologic Therapies on Airway Hyperresponsiveness and Allergic Response: A Systematic Literature Review. Journal of Asthma and Allergy. Volume 16:755-774. 2023
- The added value of haemoglobin to height, age, and sex to predict DLCO in subjects with preserved exercise capacity. PLoS ONE. 18:e0289540-e0289540. 2023
- Impact of productive and dry chronic cough on mortality in the Canadian Longitudinal Study on Aging (CLSA). Journal of Thoracic Disease. 14:5087-5096. 2022
- Narrative Review of the Mechanisms and Treatment of Cough in Asthma, Cough Variant Asthma, and Non-asthmatic Eosinophilic Bronchitis. Lung. 200:707-716. 2022
- A patient decision aid for mild asthma: Navigating a new asthma treatment paradigm. Respiratory Medicine. 201:106568-106568. 2022
- Allergen provocation tests in respiratory research: building on 50 years of experience. European Respiratory Journal. 60:2102782-2102782. 2022
- Impact of mental health and personality traits on the incidence of chronic cough in the Canadian Longitudinal Study on Aging. ERJ Open Research. 8:00119-2022. 2022
- Aerosol delivery, but not intramuscular injection, of adenovirus-vectored tuberculosis vaccine induces respiratory-mucosal immunity in humans. JCI insight. 7:e155655. 2022
- Group 2 innate lymphoid cells in patients with nonasthmatic eosinophilic bronchitis. Acta Allergologica. 77:649-652. 2022
- In memoriam of Dr. Mark FitzGerald, MD, MB, FCCP, FRCPI, FRCPC. Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 6:4-5. 2022
- Assessing cough symptom severity in refractory or unexplained chronic cough: findings from patient focus groups and an international expert panel. ERJ Open Research. 8:00667-2021. 2022
- Language and geographical location influence the incidence of chronic cough in the Canadian Longitudinal Study on Aging. ERJ Open Research. 8:00721-2021. 2022
- Positioning As-needed Budesonide–Formoterol for Mild Asthma: Effect of Prestudy Treatment in Pooled Analysis of SYGMA 1 and 2. Annals of the American Thoracic Society. 18:2007-2017. 2021
- The cost-effectiveness of as-needed budesonide-formoterol versus low-dose inhaled corticosteroid maintenance therapy in patients with mild asthma in Canada. Allergy, Asthma and Clinical Immunology. 17:108. 2021
- Defining a Severe Asthma Super-Responder: Findings from a Delphi Process. Journal of Allergy and Clinical Immunology: In Practice. 9:3997-4004. 2021
- Medical algorithms: Approach to adult asthma exacerbations. Acta Allergologica. 76:3556-3559. 2021
- Reply to “As-needed budesonide-formoterol for adolescents with mild asthma: importance of lung function”. Journal of Allergy and Clinical Immunology: In Practice. 9:4179-4180. 2021
- Breastfeeding and risk of childhood asthma: a systematic review and meta-analysis. ERJ Open Research. 7:00504-2021. 2021
- Cough symptom severity in patients with refractory or unexplained chronic cough: a systematic survey and conceptual framework. European Respiratory Review. 30:210104-210104. 2021
- Limosilactobacillus reuteri DSM‐17938 for preventing cough in adults with mild allergic asthma: A double‐blind randomized placebo‐controlled cross‐over study. Clinical and Experimental Allergy. 51:1133-1143. 2021
- Effect of anti‐IL‐5 biologics on weight and body mass index. Acta Allergologica. 76:2913-2916. 2021
- Effect of intranasal corticosteroid treatment on allergen‐induced changes in group 2 innate lymphoid cells in allergic rhinitis with mild asthma. Acta Allergologica. 76:2797-2808. 2021
- Exercise-induced bronchoconstriction and bronchodilation: investigating the effects of age, sex, airflow limitation and FEV1. European Respiratory Journal. 58:2004026-2004026. 2021
- Response of upper and lower airway inflammation to bronchial challenge with house dust mite in Chinese asthmatics: a pilot study. Journal of Thoracic Disease. 13:4988-4998. 2021
- Triple vs Dual Inhaler Therapy and Asthma Outcomes in Moderate to Severe Asthma. Journal of the American Medical Association (JAMA). 325:2466-2466. 2021
- Influence of age, sex and respiratory viruses on the rates of emergency department visits and hospitalisations with respiratory tract infections, asthma and COPD. ERJ Open Research. 7:00053-2021. 2021
- Prevalence, incidence and characteristics of chronic cough among adults from the Canadian Longitudinal Study on Aging. ERJ Open Research. 7:00160-2021. 2021
- Safety of As-Needed Budesonide-Formoterol in Mild Asthma: Data from the Two Phase III SYGMA Studies. Drug Safety. 44:467-478. 2021
- The management of mild asthma. European Respiratory Journal. 57:2003051-2003051. 2021
- ARIA‐EAACI statement on asthma and COVID‐19 (June 2, 2020). Acta Allergologica. 76:689-697. 2021
- Allergen inhalation generates pro-inflammatory oxidised phosphatidylcholine associated with airway dysfunction. European Respiratory Journal. 57:2000839-2000839. 2021
- Effect of a single day of increased as-needed budesonide–formoterol use on short-term risk of severe exacerbations in patients with mild asthma: a post-hoc analysis of the SYGMA 1 study. The Lancet Respiratory Medicine. 9:149-158. 2021
- The Impact of beta blockade on the cardio-respiratory system and symptoms during exercise. Current Research in Physiology. 4:235-242. 2021
- A golden age of asthma research. European Respiratory Journal. 56:2003820-2003820. 2020
- The Role of the TL1A/DR3 Axis in the Activation of Group 2 Innate Lymphoid Cells in Subjects with Eosinophilic Asthma. American Journal of Respiratory and Critical Care Medicine. 202:1105-1114. 2020
- CORRIGENDUM. Respirology. 25:1103-1104. 2020
- Emergency department visits and hospitalisations for asthma, COPD and respiratory tract infections: what is the role of respiratory viruses, and return to school in September, January and March?. ERJ Open Research. 6:00593-2020. 2020
- Asthma maintenance and reliever therapy. Annals of Allergy, Asthma and Immunology. 125:150-155. 2020
- Inhaled corticosteroids/formoterol as a reliever in mild asthma. Respirology. 25:795-796. 2020
- Performance Characteristics of Spirometry With Negative Bronchodilator Response and Methacholine Challenge Testing and Implications for Asthma Diagnosis. Chest. 158:479-490. 2020
- What have we learnt about asthma control from trials of budesonide/formoterol as maintenance and reliever?. Respirology. 25:804-815. 2020
- Investigations and management of chronic cough: update from the European Respiratory Society Chronic Cough Taskforce 2020. Polskie Archiwum Medycyny Wewnetrznej. 130:789-795. 2020
- The burden of exacerbations in mild asthma: a systematic review. ERJ Open Research. 6:00359-2019. 2020
- Toward personalization of asthma treatment according to trigger factors. Journal of Allergy and Clinical Immunology. 145:1529-1534. 2020
- Identifying a Neurophenotype in Severe Asthma. American Journal of Respiratory and Critical Care Medicine. 201:1024-1025. 2020
- The presence of Aspergillus fumigatus in asthmatic airways is not clearly related to clinical disease severity. Acta Allergologica. 75:1146-1154. 2020
- Fluticasone furoate/vilanterol versus fluticasone propionate in patients with asthma and exercise-induced bronchoconstriction. Journal of Asthma. 57:431-440. 2020
- The contribution of FEV 1 and airflow limitation on the intensity of dyspnea and leg effort during exercise. Insights from a real‐world cohort. Physiological Reports. 8:e14415. 2020
- Tracheobronchomegaly, cough and recurrent chest infection: Mounier-Kuhn syndrome. ERJ Open Research. 6:00138-2020. 2020
- Paradigm shift in the management of mild asthma: Focus toward a patient centered approach. Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 4:55-60. 2020
- Prevalence and contribution of respiratory viruses in the community to rates of emergency department visits and hospitalizations with respiratory tract infections, chronic obstructive pulmonary disease and asthma. PLoS ONE. 15:e0228544-e0228544. 2020
- Use of a vibrating mesh nebulizer for allergen challenge. Allergy, Asthma and Clinical Immunology. 15:73. 2019
- Cholinergic synapse pathway gene polymorphisms associated with allergen-induced late asthmatic responses. ERJ Open Research. 5:00107-2019. 2019
- Allergen challenge increases capsaicin-evoked cough responses in patients with allergic asthma. Journal of Allergy and Clinical Immunology. 144:788-795.e1. 2019
- The Global Initiative for Asthma (GINA): 25 years later. European Respiratory Journal. 54:1900598-1900598. 2019
- Asthma progression and mortality: the role of inhaled corticosteroids. European Respiratory Journal. 54:1900491-1900491. 2019
- Effect of sex on group 2 innate lymphoid cells in the airways of mild and severe asthmatics. Acta Allergologica. 74:1397-1400. 2019
- Mortality and cardiovascular and respiratory morbidity in individuals with impaired FEV1 (PURE): an international, community-based cohort study. The Lancet Global Health. 7:e613-e623. 2019
- Correlation of Clinical Atopic Dermatitis Scores with Levels of Eosinophil Progenitors in Skin after Intradermal Allergen Challenge. Journal of Allergy and Clinical Immunology. 143:AB66-AB66. 2019
- The interleukin-13 paradox in asthma: effective biology, ineffective biologicals. European Respiratory Journal. 53:1802250-1802250. 2019
- Effects of interleukin‐6 receptor blockade on allergen‐induced airway responses in mild asthmatics. Clinical and Translational Immunology. 8:e1044. 2019
- Spread the Word About CHEST in 2019. Chest. 155:1-4. 2019
- Interleukin-25 and eosinophils progenitor cell mobilization in allergic asthma. Clinical and Translational Allergy. 8:5. 2018
- Advances in the treatment of mild asthma: recent evidence. Polskie Archiwum Medycyny Wewnetrznej. 128:545-549. 2018
- Expression of IL-33 and TSLP and Their Receptors in Asthmatic Airways after Inhaled Allergen Challenge. American Journal of Respiratory and Critical Care Medicine. 198:805-807. 2018
- Two pathways, one patient; UK asthma guidelines. Thorax. 73:797-798. 2018
- Sputum cytology during late‐phase responses to inhalation challenge with different allergens. Acta Allergologica. 73:1470-1478. 2018
- Combined Analysis of Asthma Safety Trials of Long-Acting β2-Agonists. New England Journal of Medicine. 378:2497-2505. 2018
- As-Needed Budesonide–Formoterol versus Maintenance Budesonide in Mild Asthma. New England Journal of Medicine. 378:1877-1887. 2018
- Inhaled Combined Budesonide–Formoterol as Needed in Mild Asthma. New England Journal of Medicine. 378:1865-1876. 2018
- Changes in regulatory B-cell levels in bone marrow, blood, and sputum of patients with asthma following inhaled allergen challenge. Journal of Allergy and Clinical Immunology. 141:1495-1498.e9. 2018
- Giants in Chest Medicine. Chest. 153:776-777. 2018
- Methacholine Challenge: Comparison of Airway Responsiveness Produced by a Vibrating Mesh Nebulizer Versus a Jet Nebulizer. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 31:88-93. 2018
- The effects of a CCR3 inhibitor, AXP1275, on allergen-induced airway responses in adults with mild-to-moderate atopic asthma. Clinical and Experimental Allergy. 48:445-451. 2018
- Novel Blood-based Transcriptional Biomarker Panels Predict the Late-Phase Asthmatic Response. American Journal of Respiratory and Critical Care Medicine. 197:450-462. 2018
- Evolving Concepts in Asthma. Seminars in Respiratory and Critical Care Medicine. 39:001-002. 2018
- “Global strategy for asthma management and prevention: GINA executive summary.” E.D. Bateman, S.S. Hurd, P.J. Barnes, J. Bousquet, J.M. Drazen, J.M. FitzGerald, P. Gibson, K. Ohta, P. O'Byrne, S.E. Pedersen, E. Pizzichini, S.D. Sullivan, S.E. Wenzel and H.J. Zar.Eur Respir J2008; 31: 143–178.. European Respiratory Journal. 51:0751387-0751387. 2018
- IL-33 and Its Receptor ST2 after Inhaled Allergen Challenge in Allergic Asthmatics. International Archives of Allergy and Immunology. 176:133-142. 2018
- Efficacy of budesonide/formoterol maintenance and reliever therapy compared with higher-dose budesonide as step-up from low-dose inhaled corticosteroid treatment. BMC Pulmonary Medicine. 17:65. 2017
- The SYGMA programme of phase 3 trials to evaluate the efficacy and safety of budesonide/formoterol given ‘as needed’ in mild asthma: study protocols for two randomised controlled trials. Trials. 18:12. 2017
- The interaction between bronchoconstriction and cough in asthma. Thorax. 72:1144-1146. 2017
- Allergen-induced Increases in Sputum Levels of Group 2 Innate Lymphoid Cells in Subjects with Asthma. American Journal of Respiratory and Critical Care Medicine. 196:700-712. 2017
- The paradoxes of asthma management: time for a new approach?. European Respiratory Journal. 50:1701103-1701103. 2017
- Fine Particulate Air Pollution and Daily Mortality. A Nationwide Analysis in 272 Chinese Cities. American Journal of Respiratory and Critical Care Medicine. 196:73-81. 2017
- Toll‐like receptor‐induced expression of epithelial cytokine receptors on haemopoietic progenitors is altered in allergic asthma. Clinical and Experimental Allergy. 47:900-908. 2017
- Epithelial-Derived Cytokines in Asthma. Chest. 151:1338-1344. 2017
- Methacholine challenge tests to demonstrate therapeutic equivalence of terbutaline sulfate via different Turbuhaler ® devices in patients with mild to moderate asthma: Appraisal of a four-way crossover design. Pulmonary Pharmacology and Therapeutics. 44:1-6. 2017
- The Potential Role of Aspiration in the Asthmatic Airway. Chest. 151:1272-1278. 2017
- Targeting Eosinophils in Eosinophilic Granulomatosis with Polyangiitis. New England Journal of Medicine. 376:1985-1986. 2017
- Airway Hyperresponsiveness in Asthma: Measurement and Clinical Relevance. Journal of Allergy and Clinical Immunology: In Practice. 5:649-659.e2. 2017
- A pilot randomised clinical trial of mepolizumab in COPD with eosinophilic bronchitis. European Respiratory Journal. 49:1602486-1602486. 2017
- Capsaicin-evoked cough responses in asthmatic patients: Evidence for airway neuronal dysfunction. Journal of Allergy and Clinical Immunology. 139:771-779.e10. 2017
- Glucagon‐like peptide‐1 receptor expression on human eosinophils and its regulation of eosinophil activation. Clinical and Experimental Allergy. 47:331-338. 2017
- Effects of bidi smoking on all-cause mortality and cardiorespiratory outcomes in men from south Asia: an observational community-based substudy of the Prospective Urban Rural Epidemiology Study (PURE). The Lancet Global Health. 5:e168-e176. 2017
- An Official American Thoracic Society Research Statement: Current Challenges Facing Research and Therapeutic Advances in Airway Remodeling. American Journal of Respiratory and Critical Care Medicine. 195:e4-e19. 2017
- Biologics and the lung: TSLP and other epithelial cell-derived cytokines in asthma. Pharmacology and Therapeutics. 169:104-112. 2017
- POINT: Will New Anti-eosinophilic Drugs Be Useful in Asthma Management? Yes. Chest. 151:14-17. 2017
- Rebuttal From Dr O’Byrne. Chest. 151:20-21. 2017
- Should recommendations about starting inhaled corticosteroid treatment for mild asthma be based on symptom frequency: a post-hoc efficacy analysis of the START study. The Lancet. 389:157-166. 2017
- Treatment of asthma: predicting the future of atopic disease treatment Dr. Paul O’Byrne in an interview with Dr. Roman Jaeschke: part 2. Polskie Archiwum Medycyny Wewnetrznej. 126:1031-1032. 2016
- Treatment of asthma: roles of different classes of drugs Dr. Paul O’Byrne in an interview with Dr. Roman Jaeschke: part 1. Polskie Archiwum Medycyny Wewnetrznej. 126:1028-1030. 2016
- A 43-year-old man with cough, expectoration and recurrent wheezing. Journal of Thoracic Disease. 8:3468-3477. 2016
-
A dual Cys
LT 1/2 antagonist attenuates allergen‐induced airway responses in subjects with mild allergic asthma. Acta Allergologica. 71:1721-1727. 2016 - Integrated safety and efficacy analysis of once-daily fluticasone furoate for the treatment of asthma. Respiratory Research. 17:157. 2016
- The effects of a CXCR1/CXCR2 antagonist on neutrophil migration in mild atopic asthmatic subjects. Pulmonary Pharmacology and Therapeutics. 41:34-39. 2016
- Safety of long‑acting β2‑agonists: a little bit of history. Dr. Paul O’Byrne in an interview with Dr. Roman Jaeschke: part 1. Polskie Archiwum Medycyny Wewnetrznej. 126:910-911. 2016
- Safety of long‑acting ß2‑agonists: current state of knowledge. Dr. Paul O’Byrne in an interview with Dr. Roman Jaeschke: part 2. Polskie Archiwum Medycyny Wewnetrznej. 126:912-913. 2016
- Efficacy and safety of a CXCR2 antagonist, AZD5069, in patients with uncontrolled persistent asthma: a randomised, double-blind, placebo-controlled trial. The Lancet Respiratory Medicine. 4:797-806. 2016
- Efficacy and safety of multiple doses of QGE031 (ligelizumab) versus omalizumab and placebo in inhibiting allergen-induced early asthmatic responses. Journal of Allergy and Clinical Immunology. 138:1051-1059. 2016
- Measuring Eosinophils to Make Treatment Decisions in Asthma. Chest. 150:485-487. 2016
- Tiotropium for the treatment of asthma: a drug safety evaluation. Expert Opinion on Drug Safety. 15:1115-1124. 2016
- Allergen-induced Changes in Bone Marrow and Airway Dendritic Cells in Subjects with Asthma. American Journal of Respiratory and Critical Care Medicine. 194:169-177. 2016
- IL-25 Receptor Expression on Airway Dendritic Cells after Allergen Challenge in Subjects with Asthma. American Journal of Respiratory and Critical Care Medicine. 193:957-964. 2016
- Surfactant Protein-D and Asthma. Chest. 149:1121-1122. 2016
- Identifying Molecular Mechanisms of the Late-Phase Asthmatic Response by Integrating Cellular, Gene, and Metabolite Levels in Blood. Annals of the American Thoracic Society. 13:S98-S98. 2016
- Allergen-Induced Increases in Interleukin-25 and Interleukin-25 Receptor Expression in Mature Eosinophils from Atopic Asthmatics. International Archives of Allergy and Immunology. 170:234-242. 2016
- Anti-IgE and Biologic Approaches for the Treatment of Asthma. Handbook of Experimental Pharmacology. 237:131-152. 2016
- Emerging monoclonal antibodies as targeted innovative therapeutic approaches to asthma. Clinical Pharmacology and Therapeutics. 99:38-48. 2016
- Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia. Journal of Allergy and Clinical Immunology. 137:75-86.e8. 2016
- Therapeutic interventions in severe asthma. World Allergy Organization Journal. 9:40-40. 2016
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- Timing is everything: Targeting IgE to reduce asthma exacerbation risk. Journal of Allergy and Clinical Immunology. 136:1486-1487. 2015
- Fluticasone furoate (FF)/vilanterol (100/25 mcg or 200/25 mcg) or FF (100 mcg) in persistent asthma. Journal of Asthma. 52:1073-1083. 2015
- Allergen‐induced early and late asthmatic responses to inhaled seasonal and perennial allergens. Clinical and Experimental Allergy. 45:1647-1653. 2015
- T regulatory cell phenotypes in peripheral blood and bronchoalveolar lavage from non‐asthmatic and asthmatic subjects. Clinical and Experimental Allergy. 45:1654-1662. 2015
- Treatment with anti-OX40L or anti-TSLP does not alter the frequency of T regulatory cells in allergic asthmatics. Acta Allergologica. 70:1505-1508. 2015
- The Canadian Healthy Infant Longitudinal Development (CHILD) Study: examining developmental origins of allergy and asthma: Table 1. Thorax. 70:998-1000. 2015
- The Effects of Repeated Bronchoprovocation on FEV1 in Subjects with Asthma. Annals of the American Thoracic Society. 12:1589-1591. 2015
- A summary of the new GINA strategy: a roadmap to asthma control. European Respiratory Journal. 46:622-639. 2015
- Allergen-induced airway responses. European Respiratory Journal. 46:819-831. 2015
- Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial. The Lancet Respiratory Medicine. 3:692-701. 2015
- The GINA asthma strategy report: what’s new for primary care?. Primary Care Respiratory Journal. 25:15050. 2015
- Development and validation of a novel risk score for asthma exacerbations: The risk score for exacerbations. Journal of Allergy and Clinical Immunology. 135:1457-1464.e4. 2015
- Thymic stromal lymphopoietin and IL-33 modulate migration of hematopoietic progenitor cells in patients with allergic asthma. Journal of Allergy and Clinical Immunology. 135:1594-1602. 2015
- Revisiting early intervention in adult asthma. ERJ Open Research. 1:00022-2015. 2015
- Asthma and Exercise-Induced Bronchoconstriction in Athletes. New England Journal of Medicine. 372:641-648. 2015
- The Effect of Omega-3 Fatty Acids on Bronchial Hyperresponsiveness, Sputum Eosinophilia, and Mast Cell Mediators in Asthma. Chest. 147:397-405. 2015
- A Nonsteroidal Glucocorticoid Receptor Agonist Inhibits Allergen-induced Late Asthmatic Responses. American Journal of Respiratory and Critical Care Medicine. 191:161-167. 2015
- Corrigendum to “Efficacy and safety of fluticasone furoate 100 μg once-daily in patients with persistent asthma: A 24-week placebo and active-controlled randomised trial” [Res Med 108 (2014) 41–49]. Respiratory Medicine. 109:146-146. 2015
- Effects of Asm-024, A Modulator of Acetylcholine Receptor Function, On Airway Responsiveness and Allergen-Induced Responses in Patients with Mild Asthma. Canadian Respiratory Journal. 22:230-234. 2015
- Spread the Word About CHEST in 2015. Chest. 147:1-3. 2015
- Blood biomarkers of the late phase asthmatic response using RNA-Seq. Allergy, Asthma and Clinical Immunology. 10:A61-A61. 2014
- Comparison of vilanterol, a novel long-acting beta2 agonist, with placebo and a salmeterol reference arm in asthma uncontrolled by inhaled corticosteroids. Journal of Negative Results in Biomedicine. 13:9. 2014
- Efficacy and safety of once-daily fluticasone furoate 50 mcg in adults with persistent asthma: a 12-week randomized trial. Respiratory Research. 15:88. 2014
- Th17/Treg ratio derived using DNA methylation analysis is associated with the late phase asthmatic response. Allergy, Asthma and Clinical Immunology. 10:32. 2014
- Once‐daily fluticasone furoate 50 mcg in mild‐to‐moderate asthma: a 24‐week placebo‐controlled randomized trial. Acta Allergologica. 69:1522-1530. 2014
- Fluticasone Furoate–Vilanterol 100-25 mcg Compared with Fluticasone Furoate 100 mcg in Asthma: A Randomized Trial. Journal of Allergy and Clinical Immunology: In Practice. 2:553-561. 2014
- Targeting membrane-expressed IgE B cell receptor with an antibody to the M1 prime epitope reduces IgE production. Science Translational Medicine. 6:243ra85. 2014
- Myeloid dendritic cells type 2 after allergen inhalation in asthmatic subjects. Clinical and Experimental Allergy. 44:921-929. 2014
- Effects of an Anti-TSLP Antibody on Allergen-Induced Asthmatic Responses. New England Journal of Medicine. 370:2102-2110. 2014
- Part Two: Evaluation of N-methylbupropion as a Potential Bupropion Prodrug. Pharmaceuticals. 7:676-694. 2014
- Synthesis, Screening and Pharmacokinetic Evaluation of Potential Prodrugs of Bupropion. Part One: In Vitro Development. Pharmaceuticals. 7:595-620. 2014
- Once-daily fluticasone furoate (FF)/vilanterol reduces risk of severe exacerbations in asthma versus FF alone. Thorax. 69:312-319. 2014
- Natural regulatory T cells in isolated early responders compared with dual responders with allergic asthma. Journal of Allergy and Clinical Immunology. 133:696-703. 2014
- Once-daily fluticasone furoate alone or combined with vilanterol in persistent asthma. European Respiratory Journal. 43:773-782. 2014
- Th17/Treg ratio derived using DNA methylation analysis discriminates allergen-induced early from dual asthmatic responses. Allergy, Asthma and Clinical Immunology. 10:A46-A46. 2014
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OX 40L blockade and allergen‐induced airway responses in subjects with mild asthma. Clinical and Experimental Allergy. 44:29-37. 2014 - A GM-CSF/IL-33 Pathway Facilitates Allergic Airway Responses to Sub-Threshold House Dust Mite Exposure. PLoS ONE. 9:e88714-e88714. 2014
- Efficacy and safety of fluticasone furoate 100 μg once-daily in patients with persistent asthma: A 24-week placebo and active-controlled randomised trial. Respiratory Medicine. 108:41-49. 2014
- IL-25 and IL-25 Receptor Expression on Eosinophils from Subjects with Allergic Asthma. International Archives of Allergy and Immunology. 163:5-10. 2014
- Interleukin-18 expression, CD8+ T cells, and eosinophils in lungs of nonsmokers with fatal asthma. Annals of Allergy, Asthma and Immunology. 112:23-28.e1. 2014
- Respiratory Medicine at McMaster University, Hamilton, Ontario: 1968 to 2013. Canadian Respiratory Journal. 21:325-325. 2014
- T Helper 17 Cells and Related Cytokines after Allergen Inhalation Challenge in Allergic Asthmatics. International Archives of Allergy and Immunology. 165:27-34. 2014
- EAACI position statement on asthma exacerbations and severe asthma. Acta Allergologica. 68:1520-1531. 2013
- Increased serum levels of soluble IL-18 receptor complex in patients with allergic asthma.. Allergology International. 62:513-515. 2013
- Inhaled allergen bronchoprovocation tests. Journal of Allergy and Clinical Immunology. 132:1045-1055.e6. 2013
- Efficacy and Safety of Fluticasone Furoate/Vilanterol Compared With Fluticasone Propionate/Salmeterol Combination in Adult and Adolescent Patients With Persistent Asthma. Chest. 144:1222-1229. 2013
- Global differences in lung function by region (PURE): an international, community-based prospective study. The Lancet Respiratory Medicine. 1:599-609. 2013
- Myeloid dendritic cells type 2 in allergic asthma. Allergy. European Journal of Allergy and Clinical Immunology. 68:1322-1326. 2013
- Lipid mediator serum profiles in asthmatics significantly shift following dietary supplementation with omega‐3 fatty acids. Molecular Nutrition and Food Research. 57:1378-1389. 2013
- Asthma in the real world. Journal of Allergy and Clinical Immunology. 132:70-71. 2013
- Safety and tolerability of the novel inhaled corticosteroid fluticasone furoate in combination with the β2agonist vilanterol administered once daily for 52 weeks in patients ≥12 years old with asthma: a randomised trial. Thorax. 68:513-520. 2013
- The pharmacological modulation of allergen-induced asthma. Inflammopharmacology. 21:113-124. 2013
- Asthma: management of severe disease. The Lancet Respiratory Medicine. 1:e3-e4. 2013
- Screening of Stimulants Including Designer Drugs in Urine Using a Liquid Chromatography Tandem Mass Spectrometry System. Journal of Analytical Toxicology. 37:64-73. 2013
- New treatment approaches for asthma. Polskie Archiwum Medycyny Wewnetrznej. 123:11-13. 2013
- The Poorly Explored Impact of Uncontrolled Asthma. Chest. 143:511-523. 2013
- Decreased CTLA4+ and Foxp3+ CD25highCD4+ Cells in Induced Sputum from Patients with Mild Atopic Asthma. Allergology International. 62:203-213. 2013
- Gene-Metabolite Expression in Blood Can Discriminate Allergen-Induced Isolated Early from Dual Asthmatic Responses. PLoS ONE. 8:e67907-e67907. 2013
- Increased Serum Levels of Soluble IL-18 Receptor Complex in Patients with Allergic Asthma. Allergology International. 62:513-515. 2013
- Role of Monoclonal Antibodies in the Treatment of Asthma. Canadian Respiratory Journal. 20:23-25. 2013
- Asthma maintenance and reliever therapy. Annals of Allergy, Asthma and Immunology. 109:388-391. 2012
- Decreased miR-192 expression in peripheral blood of asthmatic individuals undergoing an allergen inhalation challenge. BMC Genomics. 13:655. 2012
- Risk of new onset diabetes mellitus in patients with asthma or COPD taking inhaled corticosteroids. Respiratory Medicine. 106:1487-1493. 2012
- EVS7-3 Asthma Exacerbations and Their Consequences. Japanese Journal of Allergology. 61:1405. 2012
- IL17 Allergen Inhalation to Study Mechanisms of Airway Inflammation. Japanese Journal of Allergology. 61:1288. 2012
- Plasma proteomics can discriminate isolated early from dual responses in asthmatic individuals undergoing an allergen inhalation challenge. Proteomics - Clinical Applications. 6:476-485. 2012
- The effect of montelukast, budesonide alone, and in combination on exercise-induced bronchoconstriction. Journal of Allergy and Clinical Immunology. 130:535-539.e3. 2012
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Safety and efficacy of a
CXCR 2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo‐controlled clinical trial. Clinical and Experimental Allergy. 42:1097-1103. 2012 - Combination inhaled corticosteroid and long-acting β2-agonist use and severe asthma exacerbations. Journal of Allergy and Clinical Immunology. 129:1280-1281. 2012
- Severe asthma: future treatments. Clinical and Experimental Allergy. 42:706-711. 2012
- “Effect of different asthma treatments on risk of cold-related exacerbations.” H.K. Reddel, C. Jenkins, S. Quirce, M.R. Sears, E.D. Bateman, P.M. O'Byrne, M. Humbert, R. Buhl, T. Harrison, G.G. Brusselle, A. Thorén, U. Sjöbring, S. Peterson, O. Östlund and G.S. Eriksson.Eur Respir J2011; 38: 584–593.: Figure 4. European Respiratory Journal. 39:1280-1280. 2012
- MS3-4 気管支喘息患者におけるEndothelial Progenitor Cells (EPC)の関与(MS3 成人気管支喘息2 基礎,ミニシンポジウム,第24回日本アレルギー学会春季臨床大会). Japanese Journal of Allergology. 61:465. 2012
- Peripheral Blood Gene Expression Changes during Allergen Inhalation Challenge in Atopic Asthmatic Individuals. Journal of Asthma. 49:219-226. 2012
- The airway epithelium in childhood asthma. Journal of Allergy and Clinical Immunology. 129:998-999. 2012
- Corticosteroid‐induced gene expression in allergen‐challenged asthmatic subjects taking inhaled budesonide. British Journal of Pharmacology. 165:1737-1747. 2012
- Mesenchymal cell progenitors in fibrotic lung diseases. Pneumologie. 66. 2012
- Shifting of Immune Responsiveness to House Dust Mite by Influenza A Infection: Genomic Insights. Journal of Immunology. 188:832-843. 2012
- A role for sensory nerves in the late asthmatic response. Thorax. 67:19-25. 2012
- In memoriam: Frederick E Hargreave (1938-2011). Thorax. 66:1101-1102. 2011
- Overall asthma control achieved with budesonide/formoterol maintenance and reliever therapy for patients on different treatment steps. Respiratory Research. 12:38. 2011
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- Influenza A facilitates sensitization to house dust mite in infant mice leading to an asthma phenotype in adulthood. Mucosal Immunology. 4:682-694. 2011
- Interleukin-18 and interleukin-18 receptor- expression in allergic asthma. European Respiratory Journal. 38:981-983. 2011
- Lung Homing of Endothelial Progenitor Cells in Humans with Asthma after Allergen Challenge. American Journal of Respiratory and Critical Care Medicine. 184:771-778. 2011
- Effect of different asthma treatments on risk of cold-related exacerbations. European Respiratory Journal. 38:584-593. 2011
- Allergen inhalation challenge in smoking compared with non-smoking asthmatic subjects. Clinical and Experimental Allergy. 41:1084-1090. 2011
- Sputum inflammatory cells and allergen-induced airway responses in allergic asthmatic subjects. Acta Allergologica. 66:1075-1080. 2011
- Therapeutic strategies to reduce asthma exacerbations. Journal of Allergy and Clinical Immunology. 128:257-263. 2011
- In memoriam Prof. Hisamichi Aizawa, 1950-2011. European Respiratory Journal. 37:977-977. 2011
- Effects of Interleukin-13 Blockade on Allergen-induced Airway Responses in Mild Atopic Asthma. American Journal of Respiratory and Critical Care Medicine. 183:1007-1014. 2011
- Reply. Journal of Allergy and Clinical Immunology. 127:834-834. 2011
- Risks of Pneumonia in Patients with Asthma Taking Inhaled Corticosteroids. American Journal of Respiratory and Critical Care Medicine. 183:589-595. 2011
- Comparison of the Effect of Low-Dose Ciclesonide and Fixed-Dose Fluticasone Propionate and Salmeterol Combination on Long-term Asthma Control. Chest. 139:311-318. 2011
- The promise of electronic data capture in respiratory medicine. European Respiratory Journal. 37:228-230. 2011
- Frederick E Hargreave. Canadian Respiratory Journal. 18:193-193. 2011
- Global guidelines for asthma management. Summary of the current status and future challenges. Polskie Archiwum Medycyny Wewnetrznej. 120:511-517. 2010
- Functional genomics of the peripheral blood response to allergen inhalation challenge. Allergy, Asthma and Clinical Immunology. 6:p3. 2010
- The aqueous stability of bupropion. Journal of Pharmaceutical and Biomedical Analysis. 53:376-381. 2010
- Uniform definition of asthma severity, control, and exacerbations: Document presented for the World Health Organization Consultation on Severe Asthma. Journal of Allergy and Clinical Immunology. 126:926-938. 2010
- Development and implementation of guidelines in allergic rhinitis – an ARIA‐GA2LEN paper. Acta Allergologica. 65:1212-1221. 2010
- Erratum: Severe Exacerbations and Decline in Lung Function in Asthma. American Journal of Respiratory and Critical Care Medicine. 182:983-984. 2010
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- Measuring asthma control: a comparison of three classification systems. European Respiratory Journal. 36:269-276. 2010
- Nitric oxide in exhaled breath is poorly correlated to sputum eosinophils in patients with prednisone-dependent asthma. Journal of Allergy and Clinical Immunology. 126:404-406. 2010
- Myeloid and plasmacytoid dendritic cells in induced sputum after allergen inhalation in subjects with asthma. Journal of Allergy and Clinical Immunology. 126:133-139. 2010
- Pulmonary function testing in the Emergency Department and medications prescribed at discharge: results of the Multinational Acute asthma Management, Burden, and Outcomes (MAMBO) study. Primary Care Respiratory Journal. 19:155-162. 2010
- Recent Advances in the Pathophysiology of Asthma. Chest. 137:1417-1426. 2010
- Does the current stepwise approach to asthma pharmacotherapy encourage over‐treatment?. Respirology. 15:596-602. 2010
- Overall asthma control: The relationship between current control and future risk. Journal of Allergy and Clinical Immunology. 125:600-608.e6. 2010
- Effects of budesonide and formoterol on allergen-induced airway responses, inflammation, and airway remodeling in asthma. Journal of Allergy and Clinical Immunology. 125:349-356.e13. 2010
- Obstructive Lung Disease from Conception to Old Age: Differences in the Treatment of Adults and Children with Asthma. Annals of the American Thoracic Society. 6:720-723. 2009
- Diffuse idiopathic pulmonary neuroendocrine hyperplasia, chronic eosinophilic pneumonia, and asthma. European Respiratory Journal. 34:1489-1492. 2009
- FOREWORD. Journal of Renal Care. 35:2-2. 2009
- Prolonged bronchoprotection against inhaled methacholine by inhaled BI 1744, a long-acting β2-agonist, in patients with mild asthma. Journal of Allergy and Clinical Immunology. 124:1217-1221. 2009
- The Effects of Inhaled Budesonide on Lung Function in Smokers and Nonsmokers With Mild Persistent Asthma. Chest. 136:1514-1520. 2009
- Efficacy of leukotriene receptor antagonists and synthesis inhibitors in asthma. Journal of Allergy and Clinical Immunology. 124:397-403. 2009
- Phosphodiesterase-4 inhibition in COPD. The Lancet. 374:665-667. 2009
- Safety, pharmacodynamics and pharmacokinetics of TPI 1020 in smokers with asthma. Respiratory Medicine. 103:1159-1166. 2009
- Long-Acting Beta-Agonists in Asthma REPLY. New England Journal of Medicine. 361:209-209. 2009
- Prescribing Records and the First Amendment. New England Journal of Medicine. 361:209-210. 2009
- An Official American Thoracic Society/European Respiratory Society Statement: Asthma Control and Exacerbations. American Journal of Respiratory and Critical Care Medicine. 180:59-99. 2009
- Anti-Interleukin-5 Therapy and Severe Asthma REPLY. New England Journal of Medicine. 360:2577-2577. 2009
- Dr. Nair and colleagues reply. New England Journal of Medicine. 360:2577. 2009
- Single-dose desloratadine and montelukast and allergen-induced late airway responses. European Respiratory Journal. 33:1302-1308. 2009
- Risks of Long-Acting Beta-Agonists in Achieving Asthma Control. New England Journal of Medicine. 360:1671-1672. 2009
- Circulating Fibrocytes Are an Indicator of Poor Prognosis in Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. 179:588-594. 2009
- Mepolizumab for Prednisone-Dependent Asthma with Sputum Eosinophilia. New England Journal of Medicine. 360:985-993. 2009
- Acute, but Not Resolved, Influenza A Infection Enhances Susceptibility to House Dust Mite-Induced Allergic Disease. Journal of Immunology. 182:3095-3104. 2009
- Provoked models of asthma: what have we learnt?. Clinical and Experimental Allergy. 39:181-192. 2009
- Allergen-induced Airway Inflammation and Its Therapeutic Intervention. Allergy, Asthma and Immunology Research. 1:3-3. 2009
- Severe Exacerbations and Decline in Lung Function in Asthma. American Journal of Respiratory and Critical Care Medicine. 179:19-24. 2009
- Increasing Doses of Inhaled Corticosteroids Compared to Adding Long-Acting Inhaled β 2 -Agonists in Achieving Asthma Control. Chest. 134:1192-1199. 2008
- The Safety of Long-Acting β-Agonists among Patients with Asthma Using Inhaled Corticosteroids. American Journal of Respiratory and Critical Care Medicine. 178:1009-1016. 2008
- Effects of inhaled fluticasone propionate on CTLA‐4‐positive CD4+CD25+ cells in induced sputum in mild asthmatics. Respirology. 13:1000-1007. 2008
- The safety of formoterol among patients with asthma using inhaled corticosteroids. Systematic review and meta‑analysis. Polskie Archiwum Medycyny Wewnetrznej. 118:627-635. 2008
- In Vitro Effects of Budesonide on Eosinophil-Basophil Lineage Commitment~!2008-03-03~!2008-05-27~!2008-06-13~!. Open Respiratory Medicine Journal. 2:60-66. 2008
- Modulation of β1-integrins on hemopoietic progenitor cells after allergen challenge in asthmatic subjects. Journal of Allergy and Clinical Immunology. 122:803-810. 2008
- THE EFFECT OF ALLERGEN SELECTION ON AIRWAY RESPONSES AFTER ALLERGEN CHALLENGE USED FOR THE EVALUATION OF DRUG THERAPY IN ASTHMA. Chest. 134:6P-6P. 2008
- A new perspective on concepts of asthma severity and control. European Respiratory Journal. 32:545-554. 2008
- Asthma Management by Monitoring Sputum Neutrophil Count. Chest. 134:628-630. 2008
- Exhaled nitric oxide in guideline-based asthma management. The Lancet. 372:1015-1017. 2008
- In Vivo-to-In Silico Iterations to Investigate Aeroallergen-Host Interactions. PLoS ONE. 3:e2426-e2426. 2008
- Antisense Therapy against CCR3 and the Common Beta Chain Attenuates Allergen-induced Eosinophilic Responses. American Journal of Respiratory and Critical Care Medicine. 177:952-958. 2008
- Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophilic responses. American Journal of Respiratory and Critical Care Medicine. 177:952-958. 2008
- The Inhaled Steroid Treatment As Regular Therapy in Early Asthma (START) study 5-year follow-up: Effectiveness of early intervention with budesonide in mild persistent asthma. Journal of Allergy and Clinical Immunology. 121:1167-1174. 2008
- 2007 update of the Global Initiative for Asthma management and prevention: what’s new?. Polskie Archiwum Medycyny Wewnetrznej. 118:179-180. 2008
- Sputum Eosinophils and the Response of Exercise-Induced Bronchoconstriction to Corticosteroid in Asthma. Chest. 133:404-411. 2008
- Global strategy for asthma management and prevention: GINA executive summary. European Respiratory Journal. 31:143-178. 2008
- Long-acting beta2-agonists for chronic obstructive pulmonary disease: Serious adverse events. Cochrane Database of Systematic Reviews. CD007200-CD007200. 2008
- Predictors of a more favourable response to combined therapy with salmeterol and fluticasone as initial maintenance therapy in asthma. Respiratory Medicine. 102:77-81. 2008
- The Demise of Anti–IL-5 for Asthma, or Not. American Journal of Respiratory and Critical Care Medicine. 176:1059-1060. 2007
- "HOW MUCH IS TOO MUCH? THE TREATMENT OF MILD ASTHMA". P.M. O'BYRNE. EUR RESPIR J 2007; 30: 403 406.. European Respiratory Journal. 30:1026-1026. 2007
- Circulating myeloid and plasmacytoid dendritic cells after allergen inhalation in asthmatic subjects. Acta Allergologica. 62:1139-1145. 2007
- The allergen bronchoprovocation model: an important tool for the investigation of new asthma anti‐inflammatory therapies. Acta Allergologica. 62:1101-1110. 2007
- How much is too much? The treatment of mild asthma. European Respiratory Journal. 30:403-406. 2007
- A GABAergic system in airway epithelium is essential for mucus overproduction in asthma. Nature Medicine. 13:862-867. 2007
- Acute asthma intervention: Insights from the STAY study. Journal of Allergy and Clinical Immunology. 119:1332-1336. 2007
- GINA guidelines on asthma and beyond*. Acta Allergologica. 62:102-112. 2007
- Combining LABA and ICS in patients with severe COPD. Polskie Archiwum Medycyny Wewnetrznej. 117:6-8. 2007
- Die Rolle zirkulierenden mesenchymaler Vorläuferzellen in fibrosierenden Lungenerkrankungen. Pneumologie. 61. 2007
- Exacerbations of Asthma and COPD: Definitions, Clinical Manifestations and Epidemiology. Contributions to microbiology. 14:1-11. 2007
- Understanding Allergic Asthma from Allergen Inhalation Tests. Canadian Respiratory Journal. 14:414-418. 2007
- Effectiveness of early budesonide intervention in Caucasian versus Asian patients with asthma: 3-year results of the START study. Respirology. 11:767-775. 2006
- Effectiveness of early budesonide intervention in Caucasian versus Asian patients with asthma: 3‐year results of the START study. Respirology. 11:767-775. 2006
- Effects of inhaled ciclesonide on circulating T‐helper type 1/T‐helper type 2 cells in atopic asthmatics after allergen challenge. Clinical and Experimental Allergy. 36:1417-1424. 2006
- Montelukast Treatment Attenuates the Increase in Myofibroblasts Following Low-Dose Allergen Challenge. Chest. 130:741-753. 2006
- Pharmacological management of mild or moderate persistent asthma. The Lancet. 368:794-803. 2006
- Cytokines or Their Antagonists for the Treatment of Asthma. Chest. 130:244-250. 2006
- Immunostimulatory Sequences Regulate Interferon-inducible Genes but not Allergic Airway Responses. American Journal of Respiratory and Critical Care Medicine. 174:15-20. 2006
- Effects of Early Intervention With Inhaled Budesonide on Lung Function in Newly Diagnosed Asthma. Chest. 129:1478-1485. 2006
- Effects of intranasal fluticasone and salmeterol on allergen‐induced nasal responses. Acta Allergologica. 61:731-736. 2006
- Anti‐inflammatory effects of once daily low dose inhaled ciclesonide in mild to moderate asthmatic patients. Acta Allergologica. 61:537-542. 2006
- Early intervention of recent onset mild persistent asthma in children aged under 11 yrs: the Steroid Treatment As Regular Therapy in early asthma (START) trial. Pediatric Allergy and Immunology. 17:7-13. 2006
- Effect of ciclesonide dose and duration of therapy on exercise-induced bronchoconstriction in patients with asthma. Journal of Allergy and Clinical Immunology. 117:1008-1013. 2006
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- Predictors of Loss of Asthma Control Induced by Corticosteroid Withdrawal. Canadian Respiratory Journal. 13:129-133. 2006
- β2 Déjà Vu. Chest. 129:3-5. 2006
- Concluding Statement. American Journal of Respiratory and Critical Care Medicine. 172:415-416. 2005
- Daily Inhaled Corticosteroid Treatment Should Be Prescribed for Mild Persistent Asthma. American Journal of Respiratory and Critical Care Medicine. 172:410-412. 2005
- Daily Inhaled Corticosteroid Treatment Should Not Be Prescribed for Mild Persistent Asthma. American Journal of Respiratory and Critical Care Medicine. 172:412-414. 2005
- Rebuttal from Dr. O'Byrne. American Journal of Respiratory and Critical Care Medicine. 172:414-415. 2005
- Effect of low-dose ciclesonide on allergen-induced responses in subjects with mild allergic asthma. Journal of Allergy and Clinical Immunology. 116:285-291. 2005
- Initiation, Dose Reduction, and Duration of Inhaled Corticosteroid Therapy. Immunology and Allergy Clinics of North America. 25:511-521. 2005
- Different profiles of T-cell IFN-γ and IL-12 in allergen-induced early and dual responders with asthma. Journal of Allergy and Clinical Immunology. 115:1004-1009. 2005
- In memoriam. Acta Allergologica. 60:546-547. 2005
- In memoriam Romain Pauwels. European Respiratory Journal. 25:585-586. 2005
- Protection by budesonide and fluticasone on allergen-induced airway responses after discontinuation of therapy. Journal of Allergy and Clinical Immunology. 115:745-750. 2005
- Pharmacia Allergy Research Foundation and its Award for Young Scientists in Allergy Research. Acta Allergologica. 60:269-270. 2005
- Progenitor egress from the bone marrow after allergen challenge: Role of stromal cell–derived factor 1α and eotaxin. Journal of Allergy and Clinical Immunology. 115:501-507. 2005
- Ciclesonide is effective in protecting against exercise-induced bronchoconstriction. Journal of Allergy and Clinical Immunology. 115:S1-S1. 2005
- Early intervention with budesonide in recent onset mild persistent asthma in children: START trial results. Journal of Allergy and Clinical Immunology. 115:S58-S58. 2005
- Budesonide/Formoterol Combination Therapy as Both Maintenance and Reliever Medication in Asthma. American Journal of Respiratory and Critical Care Medicine. 171:129-136. 2005
- The links between allergen skin test sensitivity, airway responsiveness and airway response to allergen. Acta Allergologica. 60:56-59. 2005
- An economic evaluation of combination treatment with budesonide and formoterol in patients with mild-to-moderate persistent asthma. Respiratory Medicine. 98:1146-1154. 2004
- Extracellular matrix regulates human airway smooth muscle cell migration. European Respiratory Journal. 24:545-551. 2004
- Role for cysteinyl leukotrienes in allergen-induced change in circulating dendritic cell number in asthma. Journal of Allergy and Clinical Immunology. 114:73-79. 2004
- Reassessing the Th2 cytokine basis of asthma. Trends in Pharmacological Sciences. 25:244-248. 2004
- The Effect of Pranlukast on Allergen-induced Bone Marrow Eosinophilopoiesis in Subjects with Asthma. American Journal of Respiratory and Critical Care Medicine. 169:915-920. 2004
- Introduction. Annals of the American Thoracic Society. 1:71-72. 2004
- Pharmacologic Interventions to Reduce the Risk of Asthma Exacerbations. Annals of the American Thoracic Society. 1:105-108. 2004
- Type 2 Cytokines in the Pathogenesis of Sustained Airway Dysfunction and Airway Remodeling in Mice. American Journal of Respiratory and Critical Care Medicine. 169:860-867. 2004
- Kinetics of Bone Marrow Eosinophilopoiesis and Associated Cytokines after Allergen Inhalation. American Journal of Respiratory and Critical Care Medicine. 169:565-572. 2004
- Leukotriene receptor antagonists for allergic rhinitis: a systematic review and meta-analysis. American Journal of Medicine. 116:338-344. 2004
- Sputum CD34+IL-5Rα+ Cells Increase after Allergen. American Journal of Respiratory and Critical Care Medicine. 169:573-577. 2004
- Effects of intranasal fluticasone and salmeterol on allergen-induced nasal inflammation and nasal electrical potential in allergic rhinitis*1. Journal of Allergy and Clinical Immunology. 113:S197-S197. 2004
- Relationship between quality of life and clinical status in asthma: a factor analysis. European Respiratory Journal. 23:287-291. 2004
- Adult Asthma Consensus Guidelines Update 2003. Canadian Respiratory Journal. 11:9A-18A. 2004
- Different Profile of Interleukin-10 Production in Circulating T Cells from Atopic Asthmatics Compared with Healthy Subjects. Canadian Respiratory Journal. 11:33-38. 2004
- Morphometric Analysis of Mouse Airways After Chronic Allergen Challenge. Laboratory Investigation. 83:1285-1291. 2003
- Allergen‐induced fluctuation in CC chemokine receptor 3 expression on bone marrow CD34+ cells from asthmatic subjects: significance for mobilization of haemopoietic progenitor cells in allergic inflammation. Immunology. 109:536-546. 2003
- The effects of an anti-CD11a mAb, efalizumab, on allergen-induced airway responses and airway inflammation in subjects with atopic asthma. Journal of Allergy and Clinical Immunology. 112:331-338. 2003
- Airway hyperresponsiveness.. Chest. 123:411S-416S. 2003
- Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial. The Lancet. 361:1071-1076. 2003
- Budesonide enhancement of eosinophil differentiation in vitro does not involved IL-5Rα overexperesion or increased p38 MAP kinase activation. Journal of Allergy and Clinical Immunology. 111:S266-S266. 2003
- Clinical Models to Compare the Safety and Efficacy of Inhaled Corticosteroids in Patients with Asthma. Canadian Respiratory Journal. 10:27-34. 2003
- Inhaled Corticosteroids for Asthma: Common Clinical Quandaries. Journal of Asthma. 40:107-118. 2003
- Dysfunction and Remodeling of the Mouse Airway Persist after Resolution of Acute Allergen-Induced Airway Inflammation. American Journal of Respiratory Cell and Molecular Biology. 27:526-535. 2002
- Effects of Montelukast and Budesonide on Airway Responses and Airway Inflammation in Asthma. American Journal of Respiratory and Critical Care Medicine. 166:1212-1217. 2002
- Effects of montelukast and budesonide on airway responses and airway inflammation in asthma. American Journal of Respiratory and Critical Care Medicine. 166:1212-1217. 2002
- The promise of and problems with evidence‐based medicine for paediatric asthma management. Acta Allergologica. 57:5-14. 2002
- Allergen-induced Increases in Bone Marrow T Lymphocytes and Interleukin-5 Expression in Subjects with Asthma. American Journal of Respiratory and Critical Care Medicine. 166:883-889. 2002
- Cysteinyl Leukotrienes Promote Human Airway Smooth Muscle Migration. American Journal of Respiratory and Critical Care Medicine. 166:738-742. 2002
- Effect of Interferon-γon Allergic Airway Responses in Interferon-γ–deficient Mice. American Journal of Respiratory and Critical Care Medicine. 166:451-456. 2002
- Effect of interferon-gamma on allergic airway responses in interferon-gamma-deficient mice. American Journal of Respiratory and Critical Care Medicine. 166:451-456. 2002
- Levalbuterol has not been established to have therapeutic advantage over racemic albuterol. Journal of Allergy and Clinical Immunology. 110:325-325. 2002
- Omalizumab and the immune system: an overview of preclinical and clinical data. Annals of Allergy, Asthma and Immunology. 89:132-138. 2002
- The Effects of Intranasal Budesonide on Allergen-induced Production of Interleukin-5 and Eotaxin, Airways, Blood, and Bone Marrow Eosinophilia, and Eosinophil Progenitor Expansion in Sensitized Mice. American Journal of Respiratory and Critical Care Medicine. 166:146-153. 2002
- The effects of intranasal budesonide on allergen-induced production of interleukin-5 and eotaxin, airways, blood, and bone marrow eosinophilia, and eosinophil progenitor expansion in sensitized mice. American Journal of Respiratory and Critical Care Medicine. 166:146-153. 2002
- Anti-allergic therapies: effects on eosinophil progenitors. Pharmacology and Therapeutics. 95:63-72. 2002
- The effect of cysteinyl leukotrienes on growth of eosinophil progenitors from peripheral blood and bone marrow of atopic subjects. Journal of Allergy and Clinical Immunology. 110:96-101. 2002
- Rapid response of circulating myeloid dendritic cells to inhaled allergen in asthmatic subjects. Clinical and Experimental Allergy. 32:818-823. 2002
- Influence of zafirlukast and loratadine on exercise-induced bronchoconstriction. Journal of Allergy and Clinical Immunology. 109:789-793. 2002
- BUDESONIDE DOSE-RESPONSE IN MILD PERSISTENT ASTHMA. American Journal of Respiratory and Critical Care Medicine. 165:1188-1189. 2002
- Budesonide dose-response in mild persistent asthma - From the authors. American Journal of Respiratory and Critical Care Medicine. 165:1189-1189. 2002
- Distribution of intranasal instillations in mice: effects of volume, time, body position, and anesthesia. American Journal of Physiology - Lung Cellular and Molecular Physiology. 282:L833-L839. 2002
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- The trials and tribulations of anti–IL-5 …. Journal of Allergy and Clinical Immunology. 109:575-575. 2002
- Airway Hyperresponsiveness and Calcium Handling by Smooth Muscle. Chest. 121:621-624. 2002
- IL-10 production in circulating T cells differs between allergen-induced isolated early and dual asthmatic responders. Journal of Allergy and Clinical Immunology. 109:281-286. 2002
- Evaluation of Asthma Control by Physicians and Patients: Comparison with Current Guidelines. Canadian Respiratory Journal. 9:417-423. 2002
- Increased Levels of Airway Neutrophils Reduces the Inhibitory Effects of Inhaled Glucocorticosteroids on Allergen-Induced Airway Eosinophils. Canadian Respiratory Journal. 9:26-32. 2002
- Inhaled Leukotriene E4, But Not Leukotriene D4, Increased Airway Inflammatory Cells in Subjects with Atopic Asthma. American Journal of Respiratory and Critical Care Medicine. 164:1495-1500. 2001
- Low Dose Inhaled Budesonide and Formoterol in Mild Persistent Asthma. American Journal of Respiratory and Critical Care Medicine. 164:1392-1397. 2001
- The trials and tribulations of IL-5, eosinophils, and allergic asthma. Journal of Allergy and Clinical Immunology. 108:503-508. 2001
- Dose-dependent Effects of Inhaled Mometasone Furoate on Airway Function and Inflammation After Allergen Inhalation Challenge. American Journal of Respiratory and Critical Care Medicine. 164:569-574. 2001
- Design and Analytic Considerations in Determining the Cost-Effectiveness of Early Intervention in Asthma from a Multinational Clinical Trial. Contemporary Clinical Trials. 22:420-437. 2001
- The Inhaled Steroid Treatment as Regular Therapy in Early Asthma (START) Study. Contemporary Clinical Trials. 22:405-419. 2001
- Formoterol was more effective than terbutaline when taken as needed for moderate to severe asthma. BMJ Evidence-Based Medicine. 6:105-105. 2001
- Adding formoterol to budesonide in moderate asthma—health economic results from the FACET study. Respiratory Medicine. 95:505-512. 2001
- Asthma outcome measures.. Current Opinion in Allergy and Clinical Immunology. 1:201-203. 2001
- Measuring asthma control in group studies: do we need airway calibre and rescue β2-agonist use?. Respiratory Medicine. 95:319-323. 2001
- Normally suppressing CD40 coregulatory signals delivered by airway macrophages to TH2 lymphocytes are defective in patients with atopic asthma. Journal of Allergy and Clinical Immunology. 107:863-870. 2001
- The reproducibility and sample size requirements of exercise-induced bronchoconstriction measurements. European Respiratory Journal. 17:581-588. 2001
- “Reactive Airways Disease”. American Journal of Respiratory and Critical Care Medicine. 163:822-823. 2001
- Th Type 1-Stimulating Activity of Lung Macrophages Inhibits Th2-Mediated Allergic Airway Inflammation by an IFN-γ-Dependent Mechanism. Journal of Immunology. 166:1471-1481. 2001
- Therapy with Efavirenz plus Indinavir in Patients with Extensive Prior Nucleoside Reverse‐Transcriptase Inhibitor Experience: A Randomized, Double‐Blind, Placebo‐Controlled Trial. Journal of Infectious Diseases. 183:392-400. 2001
- What Is New Since the Last (1999) Canadian Asthma Consensus Guidelines?. Canadian Respiratory Journal. 8:5A-27A. 2001
- The Effects of Inhaled Budesonide on Circulating Eosinophil Progenitors and Their Expression of Cytokines after Allergen Challenge in Subjects with Atopic Asthma. American Journal of Respiratory and Critical Care Medicine. 162:2139-2144. 2000
- Treatment of mild persistent asthma with low doses of inhaled budesonide alone or in combination with formoterol.. Thorax. 55:A4-A4. 2000
- Systemic aspects of allergic disease: Bone marrow responses. Journal of Allergy and Clinical Immunology. 106:S242-S246. 2000
- Eosinophilopoiesis in A Murine Model of Allergic Airway Eosinophilia: Involvement of Bone Marrow IL-5 and IL-5 Receptor α. Journal of Immunology. 165:4040-4050. 2000
- Exercise-induced Bronchoconstriction Does Not Cause Eosinophilic Airway Inflammation or Airway Hyperresponsiveness in Subjects with Asthma. American Journal of Respiratory and Critical Care Medicine. 162:1302-1307. 2000
- Measuring Asthma Control. American Journal of Respiratory and Critical Care Medicine. 162:1330-1334. 2000
- Effects of once daily dosing with inhaled budesonide on airway hyperresponsiveness and airway inflammation following repeated low‐dose allergen challenge in atopic asthmatics. Clinical and Experimental Allergy. 30:1235-1243. 2000
- Symptom Perception during Acute Bronchoconstriction. American Journal of Respiratory and Critical Care Medicine. 162:490-496. 2000
- Increased Numbers of Both Airway Basophils and Mast Cells in Sputum after Allergen Inhalation Challenge of Atopic Asthmatics. American Journal of Respiratory and Critical Care Medicine. 161:1473-1478. 2000
- Simplified quantitation of myeloid dendritic cells in peripheral blood using flow cytometry. Bioimaging. 40:50-59. 2000
- A Long-term Study of the Antiinflammatory Effect of Low-dose Budesonide Plus Formoterol versus High-dose Budesonide in Asthma. American Journal of Respiratory and Critical Care Medicine. 161:996-1001. 2000
- A long-term study of the antiinflammatory effect of low-dose budesonide plus formoterol versus high-dose budesonide in asthma. American Journal of Respiratory and Critical Care Medicine. 161:996-1001. 2000
- In Vitro Airway Responsiveness of Flinders Sensitive and Resistant Line Rats. Brain, Behavior, and Immunity. 14:62-67. 2000
- Why Does Airway Inflammation Persist? Is It Leukotrienes?. American Journal of Respiratory and Critical Care Medicine. 161:S186-S187. 2000
- Induced Sputum Cell Counts in Healthy Adults. American Journal of Respiratory and Critical Care Medicine. 161:475-478. 2000
- Induced sputum cell counts in healthy adults. American Journal of Respiratory and Critical Care Medicine. 161:475-478. 2000
- Leukotriene Bronchoconstriction Induced by Allergen and Exercise. American Journal of Respiratory and Critical Care Medicine. 161:S68-S72. 2000
- CYCLOOXYGENASE METABOLITES PLAY A DIFFERENT ROLE IN OZONE-INDUCED PULMONARY FUNCTION DECLINE IN ASTHMATICS COMPARED TO NORMALS. Inhalation Toxicology. 12:1205-1224. 2000
- Erratum: Increased numbers of both airway basophils and mast cells after allergen inhalation in atopic asthmatics (Journal of Allergy and Clinical Immunology (January)). Journal of Allergy and Clinical Immunology. 105:231. 2000
- New Considerations About Measuring Airway Hyperresponsiveness. Journal of Asthma. 37:293-302. 2000
- Protective Effects of Fluticasone on Allergen-Induced Airway Responses and Sputum Inflammatory Markers. Canadian Respiratory Journal. 7:313-319. 2000
- Circulating dendritic cells and asthma: Rapid changes following inhaled allergen. Respirology. 4. 1999
- Summary of recommendations from the Canadian Asthma Consensus Report, 1999. CANADIAN MEDICAL ASSOCIATION JOURNAL. 161. 1999
- Asthma quality of life during 1 year of treatment with budesonide with or without formoterol. European Respiratory Journal. 14:1038-1043. 1999
- Allergen-Induced Increase in Airway Responsiveness, Airway Eosinophilia, and Bone-Marrow Eosinophil Progenitors in Mice. American Journal of Respiratory Cell and Molecular Biology. 21:473-479. 1999
- Cigarette smoke aggravates experimental colitis in rats. Gastroenterology. 117:877-883. 1999
- Development and validation of a questionnaire to measure asthma control. European Respiratory Journal. 14:902-902. 1999
- Treatment of Asthma with Drugs Modifying the Leukotriene Pathway. Survey of Anesthesiology. 43:294-295. 1999
- Exacerbations of Asthma. American Journal of Respiratory and Critical Care Medicine. 160:594-599. 1999
- Kinetics of Allergen-Induced Airway Eosinophilic Cytokine Production and Airway Inflammation. American Journal of Respiratory and Critical Care Medicine. 160:640-647. 1999
- Protection against Methacholine Bronchoconstriction to Assess Relative Potency of Inhaled β2-Agonist. American Journal of Respiratory and Critical Care Medicine. 160:354-357. 1999
- Repeatability of allergen-induced airway inflammation☆☆☆★. Journal of Allergy and Clinical Immunology. 104:66-71. 1999
- The many faces of airway inflammation: Asthma and chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 159:541-566. 1999
- An Inhaled Corticosteroid, Budesonide, Reduces Baseline but Not Allergen-induced Increases in Bone Marrow Inflammatory Cell Progenitors in Asthmatic Subjects. American Journal of Respiratory and Critical Care Medicine. 159:1457-1463. 1999
- An inhaled corticosteroid, budesonide, reduces baseline but not allergen-induced increases in bone marrow inflammatory cell progenitors in asthmatic subjects. American Journal of Respiratory and Critical Care Medicine. 159:1457-1463. 1999
- Effect of Inhaled Leukotriene D4 on Airway Eosinophilia and Airway Hyperresponsiveness in Asthmatic Subjects. American Journal of Respiratory and Critical Care Medicine. 159:1562-1567. 1999
- Interleukin‐5 and allergic inflammation. Clinical and Experimental Allergy. 29:573-575. 1999
- The Many Faces of Airway Inflammation. American Journal of Respiratory and Critical Care Medicine. 159:S1-S63. 1999
- The many faces of airway inflammation - Asthma and chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 159:S41-S63. 1999
- The many faces of airway inflammation. Asthma and chronic obstructive pulmonary disease. Asthma Research Group.. American Journal of Respiratory and Critical Care Medicine. 159:S41-S63. 1999
- Are New Asthma Therapies Needed?. Journal of Clinical Pharmacology. 39:230-236. 1999
- Antileukotrienes, asthma pathogenesis and the pharmaceutical industry.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 160:209-210. 1999
- Treatment of Asthma with Drugs Modifying the Leukotriene Pathway. New England Journal of Medicine. 340:197-206. 1999
- Inhaled Corticosteroid Therapy in Newly Detected Mild Asthma. Drugs. 58:17-24. 1999
- Once-daily corticosteroid therapy in asthma: Improving compliance with budesonide - A seminar-in-print - Foreword. Drugs. 58:U4-U5. 1999
- Protective Effects of Inhaled PGE2 on Allergen-induced Airway Responses and Airway Inflammation. American Journal of Respiratory and Critical Care Medicine. 159:31-36. 1999
- Questions and answers. Drugs. 58:51-53. 1999
- Targeting Drugs to the Airways by Different Inhalation Devices. BioDrugs. 12:279-289. 1999
- The clinical expression of allergy in the lungs. Acta Allergologica. 54:7-14. 1999
- Effect of inhaled formoterol and budesonide on exacerbations of asthma. Pneumologie. 52:142-143. 1998
- Measuring efficacy and safety of different inhaled corticosteroid preparations☆☆☆★. Journal of Allergy and Clinical Immunology. 102:879-886. 1998
- Asthma pathogenesis and allergen-induced late responses☆☆☆★. Journal of Allergy and Clinical Immunology. 102:S85-S89. 1998
- Evidence for mast cell activation during exercise-induced bronchoconstriction. European Respiratory Journal. 12:345-350. 1998
- Managing Cough as a Defense Mechanism and as a Symptom. Chest. 114:133S-181S. 1998
- Pranlukast, a cysteinyl leukotriene receptor antagonist, attenuates allergen-induced early- and late-phase bronchoconstriction and airway hyperresponsiveness in asthmatic subjects. Journal of Allergy and Clinical Immunology. 102:177-183. 1998
- Enhanced Expression of GM-CSF in Differentiating Eosinophils of Atopic and Atopic Asthmatic Subjects. American Journal of Respiratory Cell and Molecular Biology. 19:55-62. 1998
- Fredrick E hargreave.. Canadian Respiratory Journal. 5 Suppl A:3A. 1998
- Allergen Challenge Increases Cell Traffic between Bone Marrow and Lung. American Journal of Respiratory Cell and Molecular Biology. 18:759-767. 1998
- Measurement of airway hyperresponsiveness: new considerations. Thorax. 53:419-424. 1998
- Increases in airway eosinophils and interleukin-5 with minimal bronchoconstriction during repeated low-dose allergen challenge in atopic asthmatics. European Respiratory Journal. 11:821-827. 1998
- Induced sputum, bronchoalveolar lavage and blood from mild asthmatics: inflammatory cells, lymphocyte subsets and soluble markers compared. European Respiratory Journal. 11:828-834. 1998
- Assessment of airway inflammation: an overview.. European Respiratory Journal. 26:6S-8S. 1998
- The utility of methacholine airway responsiveness measurements in evaluating anti-asthma drugs☆☆☆★★★. Journal of Allergy and Clinical Immunology. 101:342-348. 1998
- Release of epithelium-derived PGE(2) from canine trachea after antigen inhalation. American Journal of Physiology. 274:L220-L225. 1998
- Release of epithelium-derived PGE2from canine trachea after antigen inhalation. American Journal of Physiology - Lung Cellular and Molecular Physiology. 274:L220-L225. 1998
- Asthma treatment: antileukotriene drugs.. Canadian Respiratory Journal. 5 Suppl A:64A-70A. 1998
- Changes in Bone Marrow Inflammatory Cell Progenitors after Inhaled Allergen in Asthmatic Subjects. American Journal of Respiratory and Critical Care Medicine. 157:99-105. 1998
- Dose-response Protective Effect of Salbutamol on Methacholine Airway Responsiveness using Pressurized Metered Dose Inhalers and Turbuhalers. Canadian Respiratory Journal. 5:119-123. 1998
- Hemopoietic Mechanisms in Allergic Airway Inflammation. International Archives of Allergy and Immunology. 117:155-159. 1998
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- Effect of Regular Inhaled Albuterol on Allergen-induced Late Responses and Sputum Eosinophils in Asthmatic Subjects. American Journal of Respiratory and Critical Care Medicine. 156:1738-1745. 1997
- Myogenic and neurogenic mechanisms and arachidonate metabolites in bronchial muscle response to allergen. American Journal of Physiology - Lung Cellular and Molecular Physiology. 273:L1118-L1125. 1997
- Myogenic and neurogenic mechanisms and arachidonate metabolites in bronchial muscle response to allergen. American Journal of Physiology. 273:L1118-L1125. 1997
- Allergen-induced increases in IL-5 receptor alpha-subunit expression on bone marrow-derived CD34+ cells from asthmatic subjects. A novel marker of progenitor cell commitment towards eosinophilic differentiation.. Journal of Clinical Investigation. 100:2466-2475. 1997
- Effect of Inhaled Formoterol and Budesonide on Exacerbations of Asthma. New England Journal of Medicine. 337:1405-1411. 1997
- The Effect of Treatment with Budesonide or PGE2In Vitroon Allergen-induced Increases in Canine Bone Marrow Progenitors. American Journal of Respiratory Cell and Molecular Biology. 17:634-641. 1997
- Antileukotrienes in the Treatment of Asthma. ACP journal club. 127:472-472. 1997
- Evaluation of single-dose inhaled corticosteroid activity with an allergen challenge model☆☆☆★★★. Journal of Allergy and Clinical Immunology. 100:65-70. 1997
- Myofibroblast involvement in the allergen-induced late response in mild atopic asthma.. American Journal of Respiratory Cell and Molecular Biology. 16:664-673. 1997
- Attenuation of early and late phase allergen-induced bronchoconstriction in asthmatic subjects by a 5-lipoxygenase activating protein antagonist, BAYx 1005. Thorax. 52:348-354. 1997
- Treatment of mild asthma. The Lancet. 349:818-818. 1997
- Introduction. Chest. 111:1S-1S. 1997
- Leukotrienes in the Pathogenesis of Asthma. Chest. 111:27S-34S. 1997
- Prolonged protection against exercise-induced bronchoconstriction by the leukotriene D4–receptor antagonist cinalukast☆☆☆★. Journal of Allergy and Clinical Immunology. 99:210-215. 1997
- Exercise‐induced Bronchoconstriction: Elucidating the Roles of Leukotrienes and Prostaglandins. Pharmacotherapy. 17:31S-38S. 1997
- A comparison of the efficacy and safety of inhaled corticosteroids in asthma. Acta Allergologica. 52:1-34. 1997
- Introduction. European Respiratory Review. 7:251-252. 1997
- Induced sputum to assess airway inflammation in asthma. European Respiratory Journal. 9:2435-2436. 1996
- Effects of inhaled budesonide on allergen-induced airway responses and airway inflammation.. American Journal of Respiratory and Critical Care Medicine. 154:1267-1271. 1996
- Increased levels of CD34+ hemopoietic progenitor cells in atopic subjects.. American Journal of Respiratory Cell and Molecular Biology. 15:645-655. 1996
- Inhaled β2-Agonists in the Treatment of Asthma. New England Journal of Medicine. 335:886-888. 1996
- Allergen-induced increase in bone marrow progenitors in airway hyperresponsive dogs: regulation by a serum hemopoietic factor.. American Journal of Respiratory Cell and Molecular Biology. 15:305-311. 1996
- Transforming growth factor beta 1 (TGF beta 1) gene expression by eosinophils in asthmatic airway inflammation.. American Journal of Respiratory Cell and Molecular Biology. 15:404-409. 1996
- The role of the bone marrow in allergy and asthma. Acta Allergologica. 51:141-148. 1996
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- Airway inflammation and asthma - Similarities and dissimilarities between asthma and inflammatory bowel diseases - Discussion. Alimentary Pharmacology and Therapeutics. 10:32-35. 1996
- Effect of Inhaled Prostaglandin E2on Methacholine and Leukotriene D4Airway Responsiveness in Asthmatic Subjects. Canadian Respiratory Journal. 3:165-168. 1996
- Efficacy and Cost Benefit of Inhaled Corticosteroids in Patients Considered to Have Mild Asthma in Primary Care Practice. Canadian Respiratory Journal. 3:169-175. 1996
- Interleukin-3 in bronchial biopsies from nonasthmatics and patients with mild and allergen-induced asthma.. American Journal of Respiratory and Critical Care Medicine. 153:350-355. 1996
- The effect of regular inhaled albuterol on exercise-induced bronchoconstriction.. American Journal of Respiratory and Critical Care Medicine. 153:65-69. 1996
- The natural history of asthma. European Respiratory Review. 6:23-26. 1996
- Eosinophils as a potential source of platelet-derived growth factor B-chain (PDGF-B) in nasal polyposis and bronchial asthma.. American Journal of Respiratory Cell and Molecular Biology. 13:639-647. 1995
- EFFECT OF A LEUKOTRIENE B-4 RECEPTOR ANTAGONIST SC-53228 ON OZONE-INDUCED AIRWAY HYPERRESPONSIVENESS AND INFLAMMATION IN DOGS. American Journal of Respiratory and Critical Care Medicine. 152:1443-1448. 1995
- Effect of a leukotriene B4 receptor antagonist SC-53228 on ozone-induced airway hyperresponsiveness and inflammation in dogs.. American Journal of Respiratory and Critical Care Medicine. 152:1443-1448. 1995
- Role of airway eosinophils in the development of allergen-induced airway hyperresponsiveness in dogs.. American Journal of Respiratory and Critical Care Medicine. 152:1508-1512. 1995
- The effects of an inhaled corticosteroid on oxygen radical production by bronchoalveolar cells after allergen or ozone in dogs. European Journal of Pharmacology. 293:251-257. 1995
- Distinct immunohistochemical localization of IL-4 in human inflamed airway tissues. IL-4 is localized to eosinophils in vivo and is released by peripheral blood eosinophils.. Journal of Immunology. 155:3234-3244. 1995
- Clinical Comparisons of Inhaler Systems: What are the Important Aspects?. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 8:S39-S46. 1995
- Ozone‐induced oxygen radical release from bronchoalveolar lavage cells and airway hyper‐responsiveness in dogs.. Journal of Physiology. 486:257-265. 1995
- Regular use of inhaled albuterol and the allergen-induced late asthmatic response. Journal of Allergy and Clinical Immunology. 96:44-49. 1995
- Effects of allergen challenge on eosinophils, eosinophil cationic protein, and granulocyte-macrophage colony-stimulating factor in mild asthma.. American Journal of Respiratory and Critical Care Medicine. 151:1915-1924. 1995
- Reproducibility of allergen-induced early and late asthmatic responses. Journal of Allergy and Clinical Immunology. 95:1191-1195. 1995
- Allergen-induced oxygen radical release from bronchoalveolar lavage cells and airway hyperresponsiveness in dogs.. American Journal of Respiratory and Critical Care Medicine. 151:1526-1531. 1995
- Prostanoid enhancement of interleukin-6 production by rat peritoneal mast cells.. Journal of Immunology. 154:4759-4767. 1995
- U46619-INDUCED BRONCHOCONSTRICTION IN ASTHMATIC SUBJECTS IS MEDIATED BY ACETYLCHOLINE-RELEASE. American Journal of Respiratory and Critical Care Medicine. 151:321-324. 1995
- U46619-induced bronchoconstriction in asthmatic subjects is mediated by acetylcholine release.. American Journal of Respiratory and Critical Care Medicine. 151:321-324. 1995
- Allergen-Induced Changes in Bone Marrow Progenitors and Airway Responsiveness in Dogs. International Archives of Allergy and Immunology. 107:239-241. 1995
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- Effect of inhaled budesonide on ozone-induced airway hyperresponsiveness and bronchoalveolar lavage cells in dogs. Journal of applied physiology. 77:2578-2583. 1994
- The effects of indomethacin on refractoriness following exercise both with and without a bronchoconstrictor response. European Respiratory Journal. 7:2174-2178. 1994
- Allergen-induced changes in bone marrow progenitors and airway responsiveness in dogs and the effect of inhaled budesonide on these parameters.. American Journal of Respiratory Cell and Molecular Biology. 11:600-606. 1994
- Eicosanoids and Asthmaa. Annals of the New York Academy of Sciences. 744:251-261. 1994
- Non-Invasive Monitoring of Airway Inflammation. American Journal of Respiratory and Critical Care Medicine. 150:S100-S102. 1994
- Effect of an inhaled corticosteroid on airway eosinophils and allergen-induced airway hyperresponsiveness in dogs. Journal of applied physiology. 77:1303-1308. 1994
- Granulocyte-macrophage colony-stimulating factor, eosinophils and eosinophil cationic protein in subjects with and without mild, stable, atopic asthma. European Respiratory Journal. 7:1576-1584. 1994
- Interleukin 10 inhibits lipopolysaccharide-induced survival and cytokine production by human peripheral blood eosinophils.. Journal of Experimental Medicine (JEM). 180:711-715. 1994
- Effect of sodium cromoglycate on light racehorses with elevated metachromatic cell numbers on bronchoalveolar lavage and reduced exercise tolerance. Journal of Veterinary Pharmacology and Therapeutics. 17:237-244. 1994
- Effect of Magnitude of Airway Responsiveness and Therapy With Inhaled Corticosteroid on Histamine Tachyphylaxis in Asthma. Chest. 105:1434-1438. 1994
- Effect of inhaled PGE2 on exercise-induced bronchoconstriction in asthmatic subjects.. American Journal of Respiratory and Critical Care Medicine. 149:1138-1141. 1994
- Effect of FLAP antagonist MK-0591 on leukotriene production and ozone-induced airway responses in dogs. Journal of applied physiology. 76:1583-1588. 1994
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- Exercise-induced Refractoriness in Asthmatic Subjects Involves Leukotriene and Prostaglandin Interdependent Mechanisms. American Journal of Respiratory and Critical Care Medicine. 148:950-954. 1993
- Effect of ozone exposure in vivo on response of bronchial rings in vitro: role of intracellular Ca2+. Journal of applied physiology. 75:1315-1322. 1993
- Factors contributing to dyspnoea during bronchoconstriction and exercise in asthmatic subjects. European Respiratory Journal. 6:1004-1010. 1993
- Beclomethasone given after the early asthmatic response inhibits the late response and the increased methacholine responsiveness and cromolyn does not. Journal of Allergy and Clinical Immunology. 91:1163-1168. 1993
- Effect of a platelet activating factor antagonist, WEB 2086, on allergen induced asthmatic responses.. Thorax. 48:594-598. 1993
- Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults. European Respiratory Journal. 6:53-83. 1993
- CONSEQUENCES - QUALITY ASSURANCE AND SOCIOECONOMICS - DISCUSSION. Allergy. European Journal of Allergy and Clinical Immunology. 48:162-163. 1993
- DEFINITION, PREVALENCE AND DIAGNOSIS - DISCUSSION. Allergy. European Journal of Allergy and Clinical Immunology. 48:22-23. 1993
- EXAMPLES OF MONITORING OF INFLAMMATION IN ASTHMA - DISCUSSION. Allergy. European Journal of Allergy and Clinical Immunology. 48:143-145. 1993
- EXAMPLES OF MONITORING OF INFLAMMATION IN ASTHMA - DISCUSSION. Allergy. European Journal of Allergy and Clinical Immunology. 48:110-111. 1993
- IMMUNOCYTOCHEMICAL LOCALIZATION OF GRANULOCYTE MACROPHAGE-COLONY STIMULATING FACTOR IN CANINE BRONCHOALVEOLAR LAVAGE CELLS. Journal of Allergy and Clinical Immunology. 91:206-206. 1993
- Impact of monitoring inflammation on the management of adult asthmatic patients.. Allergy. European Journal of Allergy and Clinical Immunology. 48:153-157. 1993
- Is nedocromil sodium effective treatment for asthma?. European Respiratory Journal. 6:5-6. 1993
- NEW POSSIBILITIES IN MONITORING INFLAMMATION IN ASTHMA - DISCUSSION. Allergy. European Journal of Allergy and Clinical Immunology. 48:84-86. 1993
- PATHOPHYSIOLOGY-INFLAMMATION - DISCUSSION. Allergy. European Journal of Allergy and Clinical Immunology. 48:48-49. 1993
- PATHOPHYSIOLOGY-INFLAMMATION - DISCUSSION. Allergy. European Journal of Allergy and Clinical Immunology. 48:62-64. 1993
- Airway hyperresponsiveness: mechanisms and relevance. Pediatric Allergy and Immunology. 3:163-170. 1992
- Effect of an anti-Mo1 MAb on ozone-induced airway inflammation and airway hyperresponsiveness in dogs. American Journal of Physiology. 263:L723-L726. 1992
- FORMOTEROL COMPARED WITH BECLOMETHASONE AND PLACEBO ON ALLERGEN-INDUCED ASTHMATIC RESPONSES. American Review of Respiratory Disease. 146:1156-1160. 1992
- Formoterol Compared with Beclomethasone and Placebo on Allergen-induced Asthmatic Responses. American Journal of Respiratory and Critical Care Medicine. 146:1156-1160. 1992
- Effect of an inhaled thromboxane mimetic (U46619) on in vivo pulmonary resistance and airway hyperresponsiveness in dogs.. Journal of Physiology. 453:59-67. 1992
- The effects of H2-receptor antagonists on exercise refractoriness in asthma. Journal of Allergy and Clinical Immunology. 90:125-126. 1992
- Changes in the Cellular Profile of Induced Sputum after Allergen-induced Asthmatic Responses. American Journal of Respiratory and Critical Care Medicine. 145:1265-1269. 1992
- Effect of an Inhaled Thromboxane Mimetic (U46619) on Airway Function in Human Subjects. American Journal of Respiratory and Critical Care Medicine. 145:1270-1274. 1992
- Effects of inflammatory mediators on canine airway neuromuscular function. Canadian Journal of Physiology and Pharmacology. 70:624-634. 1992
- Clinical Relevance of Lipid Mediators in Asthma. Journal of Asthma. 29:153-163. 1992
- The Effect of Antioxidants on Ozone-induced Airway Hyperresponsiveness in Dogs. American Journal of Respiratory and Critical Care Medicine. 144:1287-1290. 1991
- MECHANISM UNDERLYING OZONE-INDUCED INVITRO HYPERRESPONSIVENESS IN CANINE BRONCHI. American Journal of Physiology. 261:L55-L62. 1991
- Mechanism underlying ozone-induced in vitro hyperresponsiveness in canine bronchi. American Journal of Physiology - Lung Cellular and Molecular Physiology. 261:L55-L62. 1991
- Isocapnic Hyperventilation for Measuring Airway Hyperresponsiveness in Asthma and in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. 143:1444-1445. 1991
- The role of thromboxane in allergen-induced asthmatic responses. European Respiratory Journal. 4:667-672. 1991
- Inhibition of Exercise-Induced Bronchoconstriction by MK-571, a Potent Leukotriene D4–Receptor Antagonist. New England Journal of Medicine. 324:1288-1288. 1991
- PROLONGED PROTECTION AGAINST METHACHOLINE-INDUCED BRONCHOCONSTRICTION BY THE INHALED BETA-2-AGONIST FORMOTEROL. American Review of Respiratory Disease. 143:998-1001. 1991
- Prolonged Protection against Methacholine-induced Bronchoconstriction by the Inhaled β2-Agonist Formoterol. American Journal of Respiratory and Critical Care Medicine. 143:998-1001. 1991
- Effect of Inflammatory Mediators on Airway Nerves and Muscle. American Journal of Respiratory and Critical Care Medicine. 143:S3-S5. 1991
- Allergen-induced Asthmatic Responses: Relationship Between Increases in Airway Responsiveness and Increases in Circulating Eosinophils, Basophils, and Their Progenitors. American Journal of Respiratory and Critical Care Medicine. 143:331-335. 1991
- Allergistis non Carborundum. Chest. 99:522-522. 1991
- 440 Changes in the cellular profile of inducedsputum after allergen-induced asthmatic responses. Journal of Allergy and Clinical Immunology. 87:249-249. 1991
- Airway responsiveness to inhaled methacholine in patients with irritable bowel syndrome. Gastroenterology. 100:68-74. 1991
- Exercise-induced bronchoconstriction. Biomedicine and Pharmacotherapy. 45:463-463. 1991
- Inhibition of Exercise-Induced Bronchoconstriction by MK-571, a Potent Leukotriene D4–Receptor Antagonist. New England Journal of Medicine. 323:1736-1739. 1990
- Long-term effects of budesonide on airway responsiveness and clinical asthma severity in inhaled steroid-dependent asthmatics. European Respiratory Journal. 3:1122-1127. 1990
- Effect of Long-term Treatment with an Inhaled Corticosteroid (Budesonide) on Airway Hyperresponsiveness and Clinical Asthma in Nonsteroid-dependent Asthmatics. American Journal of Respiratory and Critical Care Medicine. 142:832-836. 1990
- Aqueous beclomethasone diproprionate nasal spray: Regular versus “as required” use in the treatment of seasonal allergic rhinitis. Journal of Allergy and Clinical Immunology. 86:380-386. 1990
- Effect of thromboxane antagonists on ozone-induced airway responses in dogs. Journal of applied physiology. 69:880-884. 1990
- Tachyphylaxis to inhaled methacholine in normal but not asthmatic subjects. Journal of applied physiology. 69:875-879. 1990
- Urinary leukotriene E4 levels during early and late asthmatic responses†. Journal of Allergy and Clinical Immunology. 86:211-220. 1990
- Methacholine Airway Responsiveness Decreases during Exercise in Asthmatic Subjects. American Journal of Respiratory and Critical Care Medicine. 141:1414-1417. 1990
- The inhibitory influence of tracheal mucosa mounted in close proximity to canine trachealis. European Journal of Pharmacology. 178:85-89. 1990
- Eicosanoids and Inflammatory cells in Asthma. Agents and Actions Supplements. 31:85-101. 1990
- Comparison of Isocapnic Hyperventilation and Histamine or Methacholine Inhalation for the Assessment of Airway Responsiveness. Allergy and Asthma Proceedings. 10:317-321. 1989
- The role of thromboxane A2 in the pathogenesis of airway hyperresponsiveness. European Respiratory Journal. 2:782-786. 1989
- Theophylline does not inhibit allergen-induced increase in airway responsiveness to methacholine. Journal of Allergy and Clinical Immunology. 83:913-920. 1989
- Effect of indomethacin on allergen-induced asthmatic responses. Journal of applied physiology. 66:578-583. 1989
- The effect of oral prostaglandin E1 on airway responsiveness in asthmatic subjects. Pulmonary Pharmacology and Therapeutics. 2:121-124. 1989
- A New Role for Histamine H2-Receptors in Asthmatic Airways. American Journal of Respiratory and Critical Care Medicine. 138:784-788. 1988
- Early/Late Response Model: Implications for Control of Asthma and Chronic Cough in Children. Pediatric Clinics of North America. 35:969-979. 1988
- Exercise Refractoriness after Histamine Inhalation in Asthmatic Subjects. American Journal of Respiratory and Critical Care Medicine. 138:794-798. 1988
- Release of epithelium-derived relaxing factor after ozone inhalation in dogs. Journal of applied physiology. 65:1238-1243. 1988
- Airway smooth muscle responsiveness from dogs with airway hyperresponsiveness after O3 inhalation. Journal of applied physiology. 65:57-64. 1988
- Histamine Bronchoconstriction Reduces Airway Responsiveness in Asthmatic Subjects. American Journal of Respiratory and Critical Care Medicine. 137:1323-1325. 1988
- Leukotrienes, Airway Hyperresponsiveness, and Asthma. Annals of the New York Academy of Sciences. 524:282-288. 1988
- Allergen-induced airway hyperresponsiveness. Journal of Allergy and Clinical Immunology. 81:119-127. 1988
- Allergy and airway hyperresponsiveness. Bailliere's clinical immunology and allergy. 2:127-142. 1988
- Effects of inflammatory mediators on neuromuscular transmission in canine trachea in vitro.. Progress in Clinical and Biological Research. 263:167-176. 1988
- Neural transmission during ozone-induced airway hyperresponsiveness.. Progress in Clinical and Biological Research. 263:3-13. 1988
- Airway Inflammation and Hyperresponsiveness. American Journal of Respiratory and Critical Care Medicine. 136:S35-S37. 1987
- Tachyphylaxis to inhaled histamine in asthmatic subjects. Journal of applied physiology. 63:1572-1577. 1987
- Role of the parasympathetic nervous system in airway hyperresponsiveness after ozone inhalation. Journal of applied physiology. 63:1174-1179. 1987
- The pathogenesis of severe asthma: A consensus report from the workshop on pathogenesis. Journal of Allergy and Clinical Immunology. 80:428-437. 1987
- Bronchoalveolar Cell Profiles of Asthmatic and Nonasthmatic Subjects. American Journal of Respiratory and Critical Care Medicine. 136:379-383. 1987
- Late Asthmatic Responses. American Journal of Respiratory and Critical Care Medicine. 136:740-751. 1987
- Bronchoalveolar lavage does not alter airway responsiveness in asthmatic subjects.. American Journal of Respiratory and Critical Care Medicine. 135:554-556. 1987
- Asthma Terminology: Troubles in Wordland. American Journal of Respiratory and Critical Care Medicine. 134:1102-1102. 1986
- The origin of airway hyperresponsiveness. Journal of Allergy and Clinical Immunology. 78:825-832. 1986
- The responsiveness of airway smooth muscle in vitro from dogs with airway hyper-responsiveness in vivo. Clinical Science. 71:605-611. 1986
- Airway Inflammation and Airway Hyperresponsiveness. Chest. 90:575-577. 1986
- Airway Responsiveness to Leukotrienes C4 and D4 and to Methacholine in Patients with Asthma and Normal Controls. New England Journal of Medicine. 315:480-484. 1986
- The effect of indomethacin on exercise-induced bronchoconstriction and refractoriness after exercise.. American Journal of Respiratory and Critical Care Medicine. 134:69-72. 1986
- Airway Responsiveness to Histamine or Methacholine: Advances in Measurement and Interpretation. Respiration; international review of thoracic diseases. 50:72-76. 1986
- Asthma and the role of inflammation.. European Respiratory Journal. 147:16-21. 1986
- Leukotriene B4 induces airway hyperresponsiveness in dogs. Journal of applied physiology. 59:1941-1946. 1985
- Significance of thromboxane generation in ozone-induced airway hyperresponsiveness in dogs. Journal of applied physiology. 59:1918-1923. 1985
- An anti-inflammatory drug (BW755C) inhibits airway hyperresponsiveness induced by ozone in dogs. Journal of Allergy and Clinical Immunology. 76:162-166. 1985
- Mediators, airway responsiveness, and asthma. Journal of Allergy and Clinical Immunology. 76:272-276. 1985
- The effect of inhaled hexamethonium bromide and atropine sulphate on airway responsiveness to histamine. Journal of Allergy and Clinical Immunology. 76:97-103. 1985
- Irish Society of Gastroenterology. Irish Journal of Medical Science. 154:203-210. 1985
- Prostaglandin F2α increases responsiveness of pulmonary airways in dogs. Prostaglandins. 28:537-543. 1984
- Indomethacin Inhibits the Airway Hyperresponsiveness but not the Neutrophil Influx Induced by Ozone in Dogs. American Journal of Respiratory and Critical Care Medicine. 130:220-224. 1984
- Neutrophil Depletion Inhibits Airway Hyperresponsiveness Induced by Ozone Exposure. American Journal of Respiratory and Critical Care Medicine. 130:214-219. 1984
- Control of neurotransmission by prostaglandins in canine trachealis smooth muscle. Journal of applied physiology. 57:129-134. 1984
- Lung epithelial permeability: relation to nonspecific airway responsiveness. Journal of applied physiology. 57:77-84. 1984
- Airway hyperresponsiveness and changes in cell counts in bronchoalveolar lavage after ozone exposure in dogs.. American Journal of Respiratory and Critical Care Medicine. 129:288-291. 1984
- The protective effect of inhaled chlorpheniramine and atropine on bronchoconstriction stimulated by airway cooling.. American Journal of Respiratory and Critical Care Medicine. 128:611-617. 1983
- Time course of airway hyperresponsiveness induced by ozone in dogs. Journal of applied physiology. 55:1232-1236. 1983
- Bronchoconstriction Stimulated by Airway Cooling. American Journal of Respiratory and Critical Care Medicine. 128:440-443. 1983
- Importance of airway inflammation for hyperresponsiveness induced by ozone.. American Journal of Respiratory and Critical Care Medicine. 127:686-690. 1983
- Prolonged asthmatic responses to inhaled methacholine. Journal of Allergy and Clinical Immunology. 71:357-362. 1983
- Inhibition of the bronchial response to respiratory heat exchange by increasing doses of terbutaline sulphate.. Thorax. 37:913-917. 1982
- Asthma induced by cold air and its relation to nonspecific bronchial responsiveness to methacholine.. American Journal of Respiratory and Critical Care Medicine. 125:281-285. 1982
- Bronchial responsiveness to histamine or methacholine in asthma: measurement and clinical significance.. European Respiratory Journal. 121:79-88. 1982
- Cold air induced asthma: Relationship to non-specific bronchial responsiveness to methacholine. Journal of Allergy and Clinical Immunology. 69:50. 1982
- Bronchial responsiveness to histamine or methacholine in asthma: measurement and clinical significance. Journal of Allergy and Clinical Immunology. 68:347-355. 1981
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