Efficacy and Safety of Fluticasone Furoate/Vilanterol Compared With Fluticasone Propionate/Salmeterol Combination in Adult and Adolescent Patients With Persistent Asthma A Randomized Trial

Abstract

BACKGROUND: The combination of fluticasone furoate (FF), a novel inhaled corticosteroid (ICS), and vilanterol (VI), a long-acting β2 agonist, is under development as a once-daily treatment of asthma and COPD. The aim of this study was to compare the efficacy of FF/VI with fluticasone propionate (FP)/salmeterol (SAL) in patients with persistent asthma uncontrolled on a medium dose of ICS. METHODS: In a randomized, double-blind, double-dummy, …

Authors

Woodcock A; Bleecker ER; Lötvall J; O'Byrne PM; Bateman ED; Medley H; Ellsworth A; Jacques L; Busse WW

Journal

Chest, Vol. 144, No. 4, pp. 1222–1229

Publisher

Elsevier

Publication Date

10 2013

DOI

10.1378/chest.13-0178

ISSN

0012-3692

Associated Experts

Paul O'Byrne

Dean and Vice-President, Faculty of Health Sciences

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