Allergen-induced airway hyperresponsiveness

Allergen inhalation in the laboratory can lead to an early (0 to 2 hours) and late (3 to 12 hours) asthmatic response and an increase in airway hyperresponsiveness to a variety of bronchoconstrictor mediators. Also, environmental allergen exposure increases airway responsiveness, symptoms of asthma, and the amount of treatment needed to control symptoms. Allergen inhalation causes an acute inflammatory response with an influx of predominantly …