Journal article
Effect of a platelet activating factor antagonist, WEB 2086, on allergen induced asthmatic responses.
Abstract
BACKGROUND: Platelet activating factor (PAF) has been implicated in the pathogenesis of airway hyperresponsiveness in asthma. The purpose of this study was to evaluate the effects of a selective PAF antagonist (WEB 2086), given in doses known to antagonise the effects of inhaled PAF in human subjects, on allergen induced early and late asthmatic responses and on airway hyperresponsiveness.
METHODS: Eight atopic, mildly asthmatic subjects were …
Authors
Freitag A; Watson RM; Matsos G; Eastwood C; O'Byrne PM
Journal
Thorax, Vol. 48, No. 6,
Publisher
BMJ
Publication Date
June 1, 1993
DOI
10.1136/thx.48.6.594
ISSN
0040-6376