Journal article
Toll‐like receptor‐induced expression of epithelial cytokine receptors on haemopoietic progenitors is altered in allergic asthma
Abstract
BACKGROUND: Haemopoietic progenitor cells (HPC) migrate to sites of allergic inflammation where, upon stimulation with epithelial cytokines, they produce Th2 cytokines and differentiate into mature eosinophils and basophils. They also express Toll-like receptors (TLR) involved in antimicrobial responses.
OBJECTIVE: The objective of this study was to compare TLR expression on peripheral blood HPC and TLR-induced responses, in particular changes …
Authors
Tworek D; Heroux D; O'Byrne SN; Mitchell P; O'Byrne PM; Denburg JA
Journal
Clinical & Experimental Allergy, Vol. 47, No. 7, pp. 900–908
Publisher
Wiley
Publication Date
July 2017
DOI
10.1111/cea.12913
ISSN
0954-7894