Journal article
Myogenic and neurogenic mechanisms and arachidonate metabolites in bronchial muscle response to allergen
Abstract
We investigated allergen-induced airway hyperresponsiveness (AH) in bronchial tissues obtained from dogs that inhaled Ascaris suum leading to AH (RESP) in vivo or that exhibited no change (NON-RESP) as well as from dogs that inhaled saline (SHAM). RESP tissues were not hyperresponsive to KC1 or to carbachol, whereas contractions to electrical field stimulation (EFS) were reduced. This reduction was reversed partially by indomethacin and …
Authors
Janssen LJ; McGrogan I; Wattie J; O'Byrne PM; Daniel EE
Journal
American Journal of Physiology Lung Cellular and Molecular Physiology, Vol. 273, No. 6 17-6, pp. L1118–L1125
Publication Date
January 1, 1997
DOI
10.1152/ajplung.1997.273.6.l1118
ISSN
1040-0605