Initiation, Dose Reduction, and Duration of Inhaled Corticosteroid Therapy Journal Articles

abstract

• Asthma is characterized by persistent airway inflammation, which is associated with airway hyperresponsiveness and variable airflow obstruction, which accounts for the majority of symptoms experienced by asthmatic patients. Allergen sensitization and inhalation causes airway inflammation, and is likely important in the initiation and persistence of asthma in more than 50% of patients, and while allergen avoidance (or avoidance of other initiating factors, such as occupational sensitizers) can help some patients, it is often difficult to achieve. For this reason, pharmacologic treatment to reduce airway inflammation is currently the cornerstone of therapy for most individuals who have asthma.

authors

• O'Byrne, Paul

status

• published 

publication date

• August 2005

has subject area

• 1107 Immunology (FoR)
• Administration, Inhalation (MeSH)
• Adrenal Cortex Hormones (MeSH)
• Allergy (Science Metrix)
• Anti-Inflammatory Agents (MeSH)
• Asthma (MeSH)
• Dose-Response Relationship, Drug (MeSH)
• Drug Administration Schedule (MeSH)
• Humans (MeSH)
• Peak Expiratory Flow Rate (MeSH)

published in

• Immunology and Allergy Clinics of North America  Journal

keywords

• Administration, Inhalation
• Adrenal Cortex Hormones
• Anti-Inflammatory Agents
• Asthma
• Dose-Response Relationship, Drug
• Drug Administration Schedule
• Humans
• Peak Expiratory Flow Rate

Digital Object Identifier (DOI)

• 10.1016/j.iac.2005.05.005

PubMed ID

• 16054540

start page

• 511

end page

• 521

volume

• 25

issue

• 3