Conference
Bone Marrow Progenitors in Allergic Airways Diseases: Studies in Canine and Human Models
Abstract
In a canine model of Ascaris suum-inducible bronchial hyperresponsiveness, we previously demonstrated that bone marrow-derived myeloid progenitors rise within 24 h of allergen inhalation; this effect is abolished by pretreatment with inhaled budesonide. We now report that this allergen-induced bone marrow response is observable in human asthmatics, and involves increases in both neutrophil-macrophage and eosinophil-basophil progenitors, within …
Authors
Denburg JA; Inman MD; Wood L; Ellis R; Sehmi R; Dahlback M; O’Byrne P
Volume
113
Pagination
pp. 181-183
Publisher
Karger Publishers
Publication Date
1997
DOI
10.1159/000237540
Conference proceedings
International Archives of Allergy and Immunology
Issue
1-3
ISSN
1018-2438