Airway Hyperresponsiveness and Calcium Handling by Smooth Muscle Academic Article uri icon

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abstract

  • We propose that abnormal calcium handling by the airway smooth muscle may be an important determinant of airway hyperresponsiveness. The amplitude, frequency, or localization of Ca(2+) oscillations in the smooth muscle may determine the degree of airway sensitivity and reactivity, which are characteristic features of asthma.

publication date

  • February 2002

published in