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Decreased CTLA4+ and Foxp3+ CD25highCD4+ Cells in...
Journal article

Decreased CTLA4+ and Foxp3+ CD25highCD4+ Cells in Induced Sputum from Patients with Mild Atopic Asthma

Abstract

BACKGROUND: Details of the comparisons between airway and peripheral blood regulatory T cells (Tregs) in patients with atopic asthma are still unclear. The objective of this study is to investigate the profiles of both airway and circulating Tregs in atopic asthma. METHODS: We measured the numbers of Tregs and eosinophils in induced sputum and peripheral blood in 28 patients with mild atopic asthma and compared these with numbers in 18 healthy …

Authors

Kawayama T; Matsunaga K; Kaku Y; Yamaguchi K; Kinoshita T; O’Byrne PM; Hoshino T

Journal

Allergology International, Vol. 62, No. 2, pp. 203–213

Publisher

Japanese Society of Allergology

Publication Date

2013

DOI

10.2332/allergolint.12-oa-0492

ISSN

1323-8930