Journal article
Plasma proteomics can discriminate isolated early from dual responses in asthmatic individuals undergoing an allergen inhalation challenge
Abstract
PURPOSE: This proteomics study was designed to determine the utility of iTRAQ MALDI-TOF/TOF technology to compare plasma samples from carefully phenotyped mild, atopic asthma subjects undergoing allergen inhalation challenge.
EXPERIMENTAL DESIGN: Eight adult subjects with mild, allergic asthma (four early responders (ERs) and four dual responders (DRs)) participated in the allergen inhalation challenge. Blood samples were collected prior to and …
Authors
Singh A; Freue GVC; Oosthuizen JL; Kam SHY; Ruan J; Takhar MK; Gauvreau GM; O'Byrne PM; FitzGerald JM; Boulet L
Journal
Proteomics Clinical Applications, Vol. 6, No. 9-10, pp. 476–485
Publisher
Wiley
Publication Date
October 2012
DOI
10.1002/prca.201200013
ISSN
1862-8346