Journal article
Glucagon‐like peptide‐1 receptor expression on human eosinophils and its regulation of eosinophil activation
Abstract
BACKGROUND: Glucagon-like peptide-1 (GLP-1) and its receptor are part of the incretin family of hormones that regulate glucose metabolism. GLP-1 also has immune modulatory roles.
OBJECTIVES: To measure the expression of the GLP-1 receptor (GLP-1R) on eosinophils and neutrophils in normal and asthmatic subjects and evaluate effects of a GLP-1 analog on eosinophil function.
Authors
Mitchell PD; Salter BM; Oliveria JP; El‐Gammal A; Tworek D; Smith SG; Sehmi R; Gauvreau GM; Butler M; O'Byrne PM
Journal
Clinical & Experimental Allergy, Vol. 47, No. 3, pp. 331–338
Publisher
Wiley
Publication Date
March 2017
DOI
10.1111/cea.12860
ISSN
0954-7894