Journal article
Mechanism underlying ozone-induced in vitro hyperresponsiveness in canine bronchi
Abstract
The effects of ozone inhalation on the contractility of canine bronchi and the mechanisms underlying any changes observed were investigated. Ozone inhalation caused acetylcholine airway hyperresponsiveness in vivo. Isolated segments of bronchi (3rd to 5th order) from dogs previously exposed to ozone (or normal air) were mounted in organ baths. Contractile responses to electrical field stimulation (FS) in all tissues decreased in magnitude over …
Authors
Janssen LJ; O'Byrne PM; Daniel EE
Journal
American Journal of Physiology, Vol. 261, No. 2, pp. l55–l62
Publisher
American Physiological Society
Publication Date
August 1, 1991
DOI
10.1152/ajplung.1991.261.2.l55
ISSN
0002-9513