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In Vitro Airway Responsiveness of Flinders...
Journal article

In Vitro Airway Responsiveness of Flinders Sensitive and Resistant Line Rats

Abstract

Recently, we reported that freely moving Flinders sensitive line rats (FSL, selectively bred for their cholinergic hyperresponsiveness) are more susceptible to allergen-induced airway hyperresponsiveness than their control counterparts-Flinders resistant line (FRL) rats. In this study the two Flinders lines were compared for responsiveness of excised tracheal and primary bronchial smooth muscle in vitro. FSL tissues were slightly but …

Authors

Janssen LJ; Djuric VJ; Wattie J; Otis J; O'Byrne PM

Journal

Brain Behavior and Immunity, Vol. 14, No. 1, pp. 62–67

Publisher

Elsevier

Publication Date

March 2000

DOI

10.1006/brbi.1999.0573

ISSN

0889-1591