Journal article
Budesonide/Formoterol Combination Therapy as Both Maintenance and Reliever Medication in Asthma
Abstract
Asthma control is improved by combining inhaled corticosteroids with long-acting beta2-agonists. However, fluctuating asthma control still occurs. We hypothesized that in patients receiving low maintenance dose budesonide/formoterol (bud/form), replacing short-acting beta2-agonist (SABA) reliever with as-needed bud/form would provide rapid symptom relief and simultaneous adjustment in antiinflammatory therapy, thereby reducing exacerbations. In …
Authors
O'Byrne PM; Bisgaard H; Godard PP; Pistolesi M; Palmqvist M; Zhu Y; Ekström T; Bateman ED
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 171, No. 2, pp. 129–136
Publisher
American Thoracic Society
Publication Date
January 15, 2005
DOI
10.1164/rccm.200407-884oc
ISSN
1073-449X
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdolescentAdrenergic beta-AgonistsAdultAgedAged, 80 and overAnti-Inflammatory AgentsAsthmaBudesonideChildChild, PreschoolDouble-Blind MethodDrug CombinationsEthanolaminesFemaleFormoterol FumarateHumansMaleMetered Dose InhalersMiddle AgedPeak Expiratory Flow RateProportional Hazards ModelsRegression AnalysisSafety