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In Vivo-to-In Silico Iterations to Investigate...
Journal article

In Vivo-to-In Silico Iterations to Investigate Aeroallergen-Host Interactions

Abstract

BACKGROUND: Allergic asthma is a complex process arising out of the interaction between the immune system and aeroallergens. Yet, the relationship between aeroallergen exposure, allergic sensitization and disease remains unclear. This knowledge is essential to gain further insight into the origin and evolution of allergic diseases. The objective of this research is to develop a computational view of the interaction between aeroallergens and the …

Authors

Llop-Guevara A; Colangelo M; Chu DK; Moore CL; Stieber NA; Walker TD; Goncharova S; Coyle AJ; Lundblad LKA; O'Byrne PM

Journal

PLOS ONE, Vol. 3, No. 6,

Publisher

Public Library of Science (PLoS)

DOI

10.1371/journal.pone.0002426

ISSN

1932-6203