Journal article
Safety of As-Needed Budesonide-Formoterol in Mild Asthma: Data from the Two Phase III SYGMA Studies
Abstract
IntroductionBudesonide-formoterol taken as needed is an emerging treatment for mild asthma.ObjectiveWe used data from the SYGMA studies to assess the safety of As-needed budesonide-formoterol compared with As-needed terbutaline and compared with maintenance budesonide.MethodsSYGMA 1 and 2 were 52-week, double-blind, parallel-group studies in patients aged ≥ 12 years with physician-assessed mild asthma. Patients were randomized to As-needed …
Authors
FitzGerald JM; O’Byrne PM; Bateman ED; Barnes PJ; Zheng J; Ivanov S; Lamarca R; Larsdotter U; Emerath U; Jansen G
Journal
Drug Safety, Vol. 44, No. 4, pp. 467–478
Publisher
Springer Nature
Publication Date
April 2021
DOI
10.1007/s40264-020-01041-z
ISSN
0114-5916