As-Needed Budesonide–Formoterol versus Maintenance Budesonide in Mild Asthma

BACKGROUND: Patients with mild asthma often rely on inhaled short-acting β₂-agonists for symptom relief and have poor adherence to maintenance therapy. Another approach might be for patients to receive a fast-acting reliever plus an inhaled glucocorticoid component on an as-needed basis to address symptoms and exacerbation risk. METHODS: We conducted a 52-week, double-blind, multicenter trial involving patients 12 years of age or older who had …