Journal article
Interleukin‐25 and eosinophils progenitor cell mobilization in allergic asthma
Abstract
BACKGROUND: Eosinophil-lineage committed progenitor cells (EoP) migrate from the bone marrow and differentiate locally to provide an ongoing source of mature eosinophils in asthmatic inflammatory responses in the airways. Sputum levels of EoP are increased in asthmatics compared to normal controls suggesting an exaggerated eosinophilopoietic environment in the airways. Understanding what factors promote EoP traffic to the airways is important …
Authors
Tang W; Smith SG; Du W; Gugilla A; Du J; Oliveria JP; Howie K; Salter BM; Gauvreau GM; O’Byrne PM
Journal
Clinical and Translational Allergy, Vol. 8, No. 1,
Publisher
Wiley
Publication Date
December 2018
DOI
10.1186/s13601-018-0190-2
ISSN
2045-7022