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The Effects of Inhaled Budesonide on Circulating...
Journal article

The Effects of Inhaled Budesonide on Circulating Eosinophil Progenitors and Their Expression of Cytokines after Allergen Challenge in Subjects with Atopic Asthma

Abstract

Allergen inhalation by dual responder subjects with atopic asthma is associated with an increase in circulating eosinophil/basophil colony-forming units (Eo/B CFU) and granulocyte-macrophage colony- stimulating factor (GM-CSF) immunolocalization in Eo/B colony cells grown in vitro. The current study examined the effect of the inhaled corticosteroid, budesonide, on the number of allergen- induced circulating eosinophils and Eo/B CFU, and …

Authors

GAUVREAU GM; WOOD LJ; SEHMI R; WATSON RM; DORMAN SC; SCHLEIMER RP; DENBURG JA; O'BYRNE PM

Journal

American Journal of Respiratory and Critical Care Medicine, Vol. 162, No. 6, pp. 2139–2144

Publisher

American Thoracic Society

Publication Date

December 1, 2000

DOI

10.1164/ajrccm.162.6.2001120

ISSN

1073-449X