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Allergen-induced Asthmatic Responses: Relationship...
Journal article

Allergen-induced Asthmatic Responses: Relationship Between Increases in Airway Responsiveness and Increases in Circulating Eosinophils, Basophils, and Their Progenitors

Abstract

The inflammatory response during allergen-induced asthma was assessed using serial measures of peripheral blood eosinophils (Eo), basophils (B), and Eo/B progenitor cells (Eo/B-CFU). A group of 14 stable asthmatic individuals (beta 2-agonists only as needed) had inhalation provocation tests with allergen (18 tests in total) and with diluent. Serial blood samples were taken before and 1 and 24 h after the tests; methylcellulose cultures for …

Authors

Gibson PG; Manning PJ; O'Byrne PM; Girgis-Gabardo A; Dolovich J; Denburg JA; Hargreave FE

Journal

American Journal of Respiratory and Critical Care Medicine, Vol. 143, No. 2, pp. 331–335

Publisher

American Thoracic Society

Publication Date

2 1991

DOI

10.1164/ajrccm/143.2.331

ISSN

1073-449X