Journal article
Dose-dependent Effects of Inhaled Mometasone Furoate on Airway Function and Inflammation After Allergen Inhalation Challenge
Abstract
Comparisons of the potency of different inhaled corticosteroids, delivery devices, and treatment regimens in the management of asthma can only be made when outcome measurements display a dose-dependent effect. These outcomes have been difficult to identify. In this study, we compared in a randomized, double-blind, crossover design, the effects of 6 d treatment with placebo and three doses (50, 100, and 400 microg, twice daily) of mometasone …
Authors
INMAN MD; WATSON RM; RERECICH T; GAUVREAU GM; LUTSKY BN; STRYSZAK P; O'BYRNE PM
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 164, No. 4, pp. 569–574
Publisher
American Thoracic Society
Publication Date
August 15, 2001
DOI
10.1164/ajrccm.164.4.2007063
ISSN
1073-449X
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Administration, InhalationAdolescentAdultAirway ResistanceAllergensAnti-Inflammatory AgentsAsthmaBronchoconstrictor AgentsCross-Over StudiesDose-Response Relationship, DrugDouble-Blind MethodEosinophilsFemaleForced Expiratory VolumeHumansInflammationMaleMethacholine ChlorideMiddle AgedMometasone FuroatePregnadienediolsSeverity of Illness IndexSputumTime FactorsTreatment Outcome