Journal article
Prolonged Protection against Methacholine-induced Bronchoconstriction by the Inhaled β2-Agonist Formoterol
Abstract
Formoterol fumarate is a new, high-affinity, beta 2-adrenergic receptor agonist that causes bronchodilation for at least 12 h. The purpose of this study was to compare the magnitude and duration of the effect of inhalation of formoterol (12 and 24 micrograms), albuterol (200 micrograms), and placebo in terms of protection against methacholine-induced bronchoconstriction. The 16 stable adult asthmatic subjects were studied on four separate study …
Authors
Ramsdale EH; Otis J; Kline PA; Gontovnick LS; Hargreave FE; O'Byrne PM
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 143, No. 5_pt_1, pp. 998–1001
Publisher
American Thoracic Society
Publication Date
May 1991
DOI
10.1164/ajrccm/143.5_pt_1.998
ISSN
1073-449X