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Identifying Molecular Mechanisms of the Late-Phase...
Journal article

Identifying Molecular Mechanisms of the Late-Phase Asthmatic Response by Integrating Cellular, Gene, and Metabolite Levels in Blood

Abstract

RATIONALE: Individuals with allergic asthma respond differently, but reproducibly, to allergen inhalation challenge. Some individuals develop an isolated early response (early responders) (ERs), whereas others go on to develop a late response (dual responders) (DRs). It is not understood why late responses do not develop in all sensitized individuals. OBJECTIVES: The aim of this study was to identify blood biomarkers that can discriminate ERs …

Authors

Singh A; Shannon CP; Kim YW; DeMarco ML; Gauvreau GM; FitzGerald JM; Boulet L-P; O'Byrne PM; Le Cao K-A; Tebbutt SJ

Journal

Annals of the American Thoracic Society, Vol. 13 Suppl 1, No. Supplement 1,

Publisher

American Thoracic Society

Publication Date

March 2016

DOI

10.1513/annalsats.201510-694mg

ISSN

2329-6933