Effects of intranasal fluticasone and salmeterol on allergen-induced nasal inflammation and nasal electrical potential in allergic rhinitis

RationaleCombination of inhaled steroid and long-acting beta-agonists have synergistic effects in asthma. There is no information on whether such benefits are observed in patients with allergic rhinitis.MethodsThe effects of intranasal treatment with fluticasone MDI (50μg bid), salmeterol MDI (25μg bid), their combination, and placebo, on nasal symptoms, eosinophil differential cell count and albumin in nasal lavage fluid (measures of …